Megestrol Acetate

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DRUG STUDY

Date Generic Brand Classification Indication Mechanism of Dosage Adverse Nursing


Name Name Action and Reaction Considerations
Frequency
Megestr Megace Therapeutic: Palliative Antineoplastic CV:  Monitor signs
ol antineoplasti treatment of effect may result THROMBOEM of
acetate endometrial from inhibition of BOLISM,
cs, thrombophle
and breast pituitary function. edema.
hormones carcinoma, Therapeutic Effects: bitis (localized
GI: GI pain, swelling,
Pharmacolog either alone Regression of
irritation. warmth,
ic: progestins or with tumor. Increased
surgery or appetite and weight Derm: erythema,
radiation gain in patients alopecia. tenderness)
(tablets only). with AIDS. Endo: and
Treatment of asymptomatic
anorexia, pulmonary
adrenal
weight loss, embolism
suppression
and cachexia (shortness of
(chronic
associated breath, chest
therapy).
with AIDS pain, cough,
(oral Hemat:
thrombophle bloody
suspension
only). bitis. MS: sputum).
carpal tunnel Notify
syndrome. physician
immediately,
and request
objective
tests (Doppler
ultrasound,
lung scan,
others) if
thromboemb
olism is
suspected.
 Assess
peripheral
edema using
girth
measurement
s, volume
displacement,
and
measurement
of pitting
edema.
Report
increased
swelling in
feet and
ankles or a
sudden
increase in
body weight
due to fluid
retention.
 Assess signs
of carpal
tunnel
syndrome,
and
implement
physical
therapy
interventions
(physical
agents,
exercise,
splinting, and
so forth) to
decrease
symptoms.
Periodically
reevaluate
condition
with sensory
and motor
tests to help
document
treatment
effects.

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