This drug study summarizes information about the drug Megestrol acetate (Megace). Megace is an antineoplastic therapeutic classified as a progestin hormone used to palliatively treat endometrial and breast carcinoma. It works by inhibiting pituitary function and causing tumor regression. Common adverse reactions include thrombophlebitis, edema, GI irritation, alopecia, adrenal suppression, and carpal tunnel syndrome. Nurses should monitor patients for signs and symptoms of these reactions and pulmonary embolism, and implement appropriate interventions and testing if issues arise.
This drug study summarizes information about the drug Megestrol acetate (Megace). Megace is an antineoplastic therapeutic classified as a progestin hormone used to palliatively treat endometrial and breast carcinoma. It works by inhibiting pituitary function and causing tumor regression. Common adverse reactions include thrombophlebitis, edema, GI irritation, alopecia, adrenal suppression, and carpal tunnel syndrome. Nurses should monitor patients for signs and symptoms of these reactions and pulmonary embolism, and implement appropriate interventions and testing if issues arise.
This drug study summarizes information about the drug Megestrol acetate (Megace). Megace is an antineoplastic therapeutic classified as a progestin hormone used to palliatively treat endometrial and breast carcinoma. It works by inhibiting pituitary function and causing tumor regression. Common adverse reactions include thrombophlebitis, edema, GI irritation, alopecia, adrenal suppression, and carpal tunnel syndrome. Nurses should monitor patients for signs and symptoms of these reactions and pulmonary embolism, and implement appropriate interventions and testing if issues arise.
This drug study summarizes information about the drug Megestrol acetate (Megace). Megace is an antineoplastic therapeutic classified as a progestin hormone used to palliatively treat endometrial and breast carcinoma. It works by inhibiting pituitary function and causing tumor regression. Common adverse reactions include thrombophlebitis, edema, GI irritation, alopecia, adrenal suppression, and carpal tunnel syndrome. Nurses should monitor patients for signs and symptoms of these reactions and pulmonary embolism, and implement appropriate interventions and testing if issues arise.
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DRUG STUDY
Date Generic Brand Classification Indication Mechanism of Dosage Adverse Nursing
Name Name Action and Reaction Considerations Frequency Megestr Megace Therapeutic: Palliative Antineoplastic CV: Monitor signs ol antineoplasti treatment of effect may result THROMBOEM of acetate endometrial from inhibition of BOLISM, cs, thrombophle and breast pituitary function. edema. hormones carcinoma, Therapeutic Effects: bitis (localized GI: GI pain, swelling, Pharmacolog either alone Regression of irritation. warmth, ic: progestins or with tumor. Increased surgery or appetite and weight Derm: erythema, radiation gain in patients alopecia. tenderness) (tablets only). with AIDS. Endo: and Treatment of asymptomatic anorexia, pulmonary adrenal weight loss, embolism suppression and cachexia (shortness of (chronic associated breath, chest therapy). with AIDS pain, cough, (oral Hemat: thrombophle bloody suspension only). bitis. MS: sputum). carpal tunnel Notify syndrome. physician immediately, and request objective tests (Doppler ultrasound, lung scan, others) if thromboemb olism is suspected. Assess peripheral edema using girth measurement s, volume displacement, and measurement of pitting edema. Report increased swelling in feet and ankles or a sudden increase in body weight due to fluid retention. Assess signs of carpal tunnel syndrome, and implement physical therapy interventions (physical agents, exercise, splinting, and so forth) to decrease symptoms. Periodically reevaluate condition with sensory and motor tests to help document treatment effects.