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    Drug Study: Saluron

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    Hydroflumethiazide is a thiazide diuretic used to treat edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid or estrogen therapy. It works by inhibiting sodium-chloride reabsorption in the distal convoluted tubule. Common adverse reactions include gastrointestinal issues, dizziness, and hypokalemia. Nursing considerations include monitoring for fluid and electrolyte imbalances like hyponatremia, hypokalemia, and hypocalcemia.

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    Drug Study: Saluron

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    32 views4 pages
    Hydroflumethiazide is a thiazide diuretic used to treat edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid or estrogen therapy. It works by inhibiting sodium-chloride reabsorption in the distal convoluted tubule. Common adverse reactions include gastrointestinal issues, dizziness, and hypokalemia. Nursing considerations include monitoring for fluid and electrolyte imbalances like hyponatremia, hypokalemia, and hypocalcemia.

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    Hydroflumethiazide

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    Hydroflumethiazide is a thiazide diuretic used to treat edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid or estrogen therapy. It works by inhibiting sodium-chloride reabsorption in the distal convoluted tubule. Common adverse reactions include gastrointestinal issues, dizziness, and hypokalemia. Nursing considerations include monitoring for fluid and electrolyte imbalances like hyponatremia, hypokalemia, and hypocalcemia.

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    © All Rights Reserved
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    32 views4 pages

    Drug Study: Saluron

    Uploaded by

    unkown user
    Hydroflumethiazide is a thiazide diuretic used to treat edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid or estrogen therapy. It works by inhibiting sodium-chloride reabsorption in the distal convoluted tubule. Common adverse reactions include gastrointestinal issues, dizziness, and hypokalemia. Nursing considerations include monitoring for fluid and electrolyte imbalances like hyponatremia, hypokalemia, and hypocalcemia.

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    DRUG STUDY

    Date Generic Brand Classificatio Indication Mechanism Dosage & Time Adverse Nursing
    Name Name n of Action Frequency Given Reaction Consideration
    10-11- Hydroflu Saluron Therapeutic: Used as Hydroflumet 50 mg Gastrointesti All patients receiving
    21 methiazid diuretics adjunctive hiazide is a daily nal system thiazide therapy should
    e therapy in thiazide reactions: be observed for clinical
    Pharmacologi edema diuretic that anorexia, signs of fluid or
    c: loop associated inhibits gastric electrolyte imbalance,
    diuretics with water irritation, namely, hyponatremia.
    congestive reabsorption nausea, hypochloremic
    heart in the vomiting, alkalosis, and
    failure, nephron by cramping, hypokalemia. Serum
    hepatic inhibiting the diarrhea, and urine electrolyte
    cirrhosis, sodium- constipation, determinations are
    and chloride jaundice particularly important
    corticoster symporter (intrahepatic when the patient is
    oid and (SLC12A3) cholestatic vomiting excessively or
    estrogen in the distal jaundice), receiving parenteral
    therapy. convoluted pancreatitis. fluids. Medication such
    Also used tubule, as digitalis may also
    in the which is Central influence serum
    manageme responsible nervous electrolytes. Warning
    nt of for 5% of system signs, irrespective of
    hypertensi total sodium reactions: cause, are: dryness of
    on either reabsorption. dizziness, mouth, thirst, weakness,
    as the sole Normally, vertigo, lethargy, drowsiness,
    therapeutic the sodium- parathesias, restlessness, muscle
    agent or to chloride headache, pains or cramps,
    enhance symporter xanthopsia. muscular fatigue,
    the effect transports hypotension, oliguria,
    of other sodium and Hematologic tachycardia, and
    antihypert chloride reactions: gastrointestinal
    ensive from the leukopenia, disturbances such as
    drugs in lumen into nausea and vomiting.
    the more the epithelial agranulocyto
    severe cell lining sis, Hypokalemia may
    forms of the distal thrombocyto develop with thiazides
    hypertensi convoluted penia, as with any other potent
    on. tubule. The aplastic diuretic, especially with
    energy for anemia. brisk diuresis. when
    this is severe cirrhosis is
    provided by Dermatologi present, or during
    a sodium c- concomitant use of
    gradient Hypersensiti corticosteroids,
    established vity including ACTH.
    by sodium- reactions:
    potassium purpura, Interference with
    ATPases on photosensiti adequate oral
    the vity, rash, electrolyte intake will
    basolateral urticaria, also contribute to
    membrane. necrotizing hypokalemia. Digitalis
    Once sodium angiitis therapy may exaggerate
    has entered (vasculitis) the metabolic effects of
    the cell, it is (cutaneous hypokalemia, especially
    transported vasculitis). with respect to
    out into the myocardial activity.
    basolateral Cardiovascul
    interstitium ar reaction: Any chloride deficit is
    via the orthostatic generally mild and
    sodium- hypotension usually does not require
    potassium may occur specific treatment,
    ATPase, and may be except under
    causing an aggravated extraordinary
    increase in by alcohol, circumstances (as in
    the barbiturates, liver disease or renal
    osmolarity of or narcotics. disease). Dilutional
    the
    interstitium, Other: hyponatremia may
    thereby hyperglycem occur in edematous
    establishing ia, patients in hot weather.
    an osmotic glycosuria, Appropriate therapy is
    gradient for hyperuricem water restriction, rather
    water ia, muscle than administration of
    reabsorption. spasm, salt, except in rare
    By blocking weakness, instances when the
    the sodium- restlessness. hyponatremia is life-
    chloride threatening. In actual
    symporter, salt depletion,
    Hydroflumet appropriate replacement
    hiazide is the therapy of choice.
    effectively
    reduces the Hyperuricemia may
    osmotic occur or frank gout may
    gradient and be precipitated in
    water certain patients
    reabsorption receiving thiazide
    throughout therapy.
    the nephron.
    Insulin requirements in
    diabetic patients may be
    increased, decreased, or
    unchanged. Latent
    diabetes mellitus may
    become manifested
    during thiazide
    administration.

    Thiazide drugs may


    increase the
    responsiveness to
    tubocurarine.

    The antihypertensive
    effects of the drug may
    be enhanced in the
    postsympathectomy
    patient.

    Thiazides may decrease


    arterial responsiveness
    to norepinephrine. This
    diminution is not
    sufficient to preclude
    effectiveness of the
    pressor agent for
    therapeutic use.

    If progressive renal
    impairment becomes
    evident, as indicated by
    rising nonprotein
    nitrogen or blood urea
    nitrogen, a careful
    reappraisal of therapy is
    necessary with
    consideration given to
    withholding or
    discontinuing diuretic
    therapy.

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