DRUG STUDY MECHANISM OF INDICATIONS CONTRAINDICATIONS ADVERSE NURSING CARE

ACTION EFFECTS
GENERIC NAME: Description: Clindamycin is Hypersensitivity hardness, pain, or a  Followed the 10
Nalbuphine is a indicated in the soft, painful bump in Rights of Drug
phenanthrene treatment of serious the area where Administration.
BRAND NAME: derivative w/ mixed infections, when clindamycin was  Assess dizziness
opioid agonist and caused by injected that might affect
antagonist activity clindamycin unpleasant or gait, balance, and
PATIENT’S DOSE: (agonist at kappa susceptible strains metallic taste in the other functional
opiate receptor; partial of gram-positive mouth activities.
antagonist at μ aerobes such as nausea  Use appropriate
ROUTE OF receptor). It inhibits the streptococci, vomiting pain scales (visual
ADMINISTRATION: ascending pain pneumococci and joint pain analogue scales,
pathways, alters the staphylococci, or by white patches in the others) to
perception of and susceptible mouth document
CLASSIFICATION: response to pain by anaerobic bacteria thick, white vaginal whether this drug
binding to opiate discharge is successful in
receptors in the CNS. It burning, itching, and helping manage
also produces swelling of the the patient's pain.
generalised CNS vagina  Help patient
depression. explore other
Onset: 2-3 min (IV); nonpharmacologic
<15 min (IM/SC). methods to
Duration: 3-6 hr. reduce chronic
Pharmacokinetics: pain, such as
Absorption: Time to relaxation
peak plasma techniques,
concentration: 30 min exercise,
(IM). counseling, and
Distribution: Crosses so forth.
the placenta and  Monitor patient
distributed in breast response to
milk (small amounts). therapy
Plasma protein binding:  Monitor for
Approx 50%. adverse effects
Metabolism: Monitor patient
Undergoes extensive compliance to
first-pass metabolism in drug therapy.
GI mucosa and liver.
Excretion: Via urine
and faeces (as
unchanged drug and
 conjugates). Elimination
half-life: 5 hr

DRUG STUDY MECHANISM OF INDICATIONS CONTRAINDICATIONS ADVERSE EFFECTS NURSING CARE

 ACTION
GENERIC NAME: Description: Clindamycin is Contraindicated in Fungal overgrowth,  Checked the
CLINDAMYCIN Clindamycin is a indicated for the patients previously found pseudomembranous doctor’s order
lincosamide antibiotic treatment of serious to be sensitive to colitis, and assure the
BRAND NAME: used to treat serious infections caused by clindamycin or lincomycin hypersensitivity, correct
DALANIN-C infections caused by susceptible anaerobic or to any component of Stevens-Johnson preparation.
susceptible anaerobic, bacteria, as well as the formulation. syndrome,  Followed the
PATIENT’S DOSE: streptococcal, susceptible hives, 10 Rights of
170 MG IV Q6 x staphylococcal, and Drug
staphylococci, low blood pressure
ANST pneumococcal Administration.
streptococci, and (hypotension),
bacteria.  Informed the
ROUTE OF Onset: immediate pneumococci. Used nausea,
patient ir the
ADMINISTRATION: Duration: 8-12 hr. topically, it is indicated blood clot,
SO about the
IV Pharmacokinetics: for the treatment of granulocytopenia,
medication
Absorption: acne vulgar is and is low white blood cell before
CLASSIFICATION: Distribution: Crosses available in count (neutropenia), administering
ANTIBIOTIC the placenta and combination with low platelet count it.
distributed in breast benzoyl peroxide10 or (thrombocytopenia),  Monitor signs
milk (small amounts). tretinoin for this polyarthritis, of allergic
Plasma protein purpose. Clindamycin kidney dysfunction, reactions and
binding: Hepatic 2-3 hr is also indicated as a vomiting, anaphylaxis,
Metabolism:. vaginal cream, diarrhea, including
Excretion: Via urine suppository, or gel for stomach pain, pulmonary
and feces the treatment of joint pain, symptoms
bacterial vaginosis in vaginal itching or (tightness in
non-pregnant females discharge, the throat and
skin rash or itching, chest,
heartburn, wheezing,
sore throat, or cough
dyspnea) or
changes in bowel habits
skin reactions
(especially in older
(rash, pruritus,
adults). urticaria).
 Notify
physician or
nursing staff
immediately if
these
reactions
occur.
DRUG STUDY MECHANISM OF INDICATIONS CONTRAINDICATIONS ADVERSE NURSING CARE
ACTION EFFECTS
GENERIC NAME: Description:  Contraindicated Abdominal pain, • Followed the
IBUPROFEN Ibuprofen, an NSAID, Ibuprofen is a in patients diarrhea, nausea, 10 Rights of Drug
has analgesic, anti- medication used to hypersensitive to vomiting, GI bleeding, Administration.
BRAND NAME: inflammatory and manage and treat drug and in those headache, dizziness, • Instruct the
antipyretic properties. inflammatory diseases, with angioedema, anxiety, fatigue, patient to report severe
PATIENT’S DOSE: It inhibits rheumatoid disorders, syndrome of nasal malaise, fatigue, cramping for increased
200 MG/ 5 MLQ6 cyclooxygenase-1 and mild to moderate pain, drowsiness bleeding.
polyps, or
2 thereby, reducing
fever, dysmenorrhea, bronchospastic • Instruct the
ROUTE OF the production of
and osteoarthritis. It is reaction to aspirin patient to report any of
ADMINISTRATION: prostaglandin
IV precursors. also available as an or other NSAIDS. the following: Cold or
Onset: Oral: over-the-counter  Contraindicated numb fingers or toes,
CLASSIFICATION: Analgesic: Within 30- medication for pain, in pregnant nausea or vomiting,
NSAIDS 60 minutes. usually mild. It is in the women. chest or muscle pain.
Duration: Antipyretic: non-steroidal anti- • Monitor blood
6-8 hours (oral). inflammatory drug pressure regularly while
Pharmacokinetics: (NSAID) class of taking this medication.
Absorption: Rapidly medications. • Monitor
absorbed from the patient response to
gastrointestinal tract; therapy
partially into the skin. • Monitor for
Food intake decreases adverse effects
absorption rate. • Monitor
Bioavailability: 80%. patient compliance to
Time to peak plasma drug therapy
concentration: 1-2
hours (tab); 1 hour
(oral susp).
Distribution: Enters
breast milk. Volume of
distribution: 0.12 L/kg
(oral). Plasma protein
binding: >99%.
Metabolism:
Metabolized in the
liver via oxidation.
Excretion: Mainly via
urine (45-80% as
metabolites, approx.
1% as unchanged
drug, 14% as
conjugated); feces.
Elimination half-life:
Approx 2 hours (oral);
2.22-2.44 hours (IV).
DRUG STUDY MECHANISM OF INDICATIONS CONTRAINDICATIONS ADVERSE NURSING CARE
ACTION EFFECTS
GENERIC NAME: Description: NasoClear is indicated Drug allergy, diarrhea Irritation in the nose,  Checked the
SODIUM CHLORIDE NasoClear saline to help provide relief (loose motion), kidney stinging doctor’s order
nasal spray is used to from nasal congestion; disease, heart disease and assure
BRAND NAME: treat nasal congestion cold or flu symptoms; the correct
NASOCLEAR NASAL (blocked nose) caused preparation.
nasal irritation due to
SPRAY due to allergies or the
common cold. It pollen, dust mites,
mold and pollution;  Informed the
PATIENT’S DOSE: loosens the mucous
nasal allergies; upper patient ir the
2 SPRAY IN EACH inside the nose and
airway cough syndrome SO about the
NOSETRILL 2X A provides relief from
medication
DAY nasal congestion. (postnasal drip)
before
administering
ROUTE OF it.
ADMINISTRATION:  Monitor signs
of allergic
reactions and
CLASSIFICATION: anaphylaxis,
DECONGESTANT including
pulmonary
symptoms
(tightness in
the throat and
chest,
wheezing,
cough
dyspnea) or
skin reactions
(rash, pruritus,
urticaria).
 Notify
physician or
nursing staff
immediately if
these
reactions
occur.