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Organic acids in leaves and rinds of Garcinia indica (Kokam) were determined by high-performance liquid chromatography. The major organic acid in leaves and rinds has been found to be ( − )-hydroxycitric acid present to the extent of... more
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      Analytical ChemistryCalibrationFruitCoefficient of Variation
Effect of nutritionally enriched coffee consumption on aerobic and anaerobic exercise performance. J. Strength Cond. Res. 21(2):456-459. 2007.-The purpose of this study was to compare nutritionally enriched JavaFit coffee (JF) to... more
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    •   14  
      Strength & ConditioningCoffeeStrengthHeart rate
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    • Garcinia kola
In order to find the strategies to ensure the sustainable management of natural's resources and especially woody plants in the Congo Basin, a study was carried out on the floristic diversity of woody plants and the structure of Garcinia... more
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    •   4  
      DiversityCameroonSustainable forestry managementGarcinia kola
Context: Garcinia hombroniana Pierre, known as manggis hutan in Malaysia is a rich source of xanthones and benzophenones. Objectives: This study was aimed to isolate and characterize potential cholinesterase inhibitors from the extracts... more
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      AntioxidantsCholinesterasesHorsesCholinesterase inhibitors
Ethnopharmacological relevance: Garcinia kola seed is commonly used in African Traditional Medicine as a remedy for liver disorders, hepatitis, bronchitis, throat infections as well as an aphrodisiac and fertility enhancing substance.... more
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    •   9  
      PharmacologyBiochemistryPharmacyToxicology
A rapid, sensitive and simple reverse-phase high-performance liquid chromatographic–electrospray ionization–mass spectrometry method for simultaneous determination of cleomiscosin A and cleomiscosin B has been developed and validated. The... more
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      Analytical ChemistryBiomedicalHPLCFruit
(−) Hydroxycitric acid (HCA), an active ingredient extracted from the Garcinia cambogia fruit rind, has been commonly used as a dietary supplement for weight management. Given the controversy over HCA related testicular toxicity in animal... more
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      Animal StudiesComplementary and Alternative MedicinePlant BiologySex Hormones
Khaya senegalensis Desr & Juss and Garcinia kola Heckel are two medicinal forest trees species that provide as well lots of meaningful Non Timber Forest Products as Forest Timber Products. Those two species are undergoing many threats... more
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    •   4  
      Climate ChangeEcological Niche ModelingKhaya senegalensisGarcinia kola
Freshly collected fruits were extracted for the seeds and air dried for 3 days. The coat of the seeds were removed and subjected to 5 treatments namely: no soaking (T1), soaking for 24 hours (T2), 48 hours (T3), 72 hours (T4) and 96 hours... more
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      LightGarcinia kolaSEED
Article CITATIONS 0 READS 29 6 authors, including: Some of the authors of this publication are also working on these related projects: Modulation of β-cell functions through enzymatic and genetic changes caused by immunomodulatory... more
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    •   67  
      Molecular BiologyAnimal BehaviorPainComplementary and Alternative Medicine
The present study was carried out to evaluate the ameliorative effects of kolaviron (a biflavonoid from the seeds of Garcinia kola ) and curcumin (from the rhizome, Curcuma longa L.) on the di-n-butylphthalate (DBP)-induced testicular... more
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      Oxidative StressFlavonoidsCurcuminChemoprevention
The antispasmodic and spasmolytic effects of methanolic extract of seeds of Garcinia kola Heckel were studied on smooth muscle preparations in vitro. The influence of the extract on rat duodenum, jejunum and ileum was investigated using... more
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      PharmacologyPharmacyToxicologyAcetylcholine
Background and Aim: Garcinia kola seed (GKS) is used to prevent and cure a number of gastric-related ailments. GKS contain a copious amount of polyphenols and can be utilized as a natural growth promoter in the nutrition of weaned... more
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      MedicineAnimal NutritionRabbitGarcinia kola
The composition of the volatile oil obtained by hydrodistillation from the fruit peel of Garcinia brasiliensis (Mart.) Planch. et Triana was determined by GC/MS. A total of 38 components were identified, including g-muurolene (10.3%),... more
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    •   15  
      ChemistryOrganic ChemistryInflammationAntioxidants
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    •   25  
      WaterGastroenterologyComplementary and Alternative MedicinePlant Biology
The aim of this study was to investigate the effect of ingestion of crude ethanol extract of Garcinia kola seed on erythrocytes. Fifty male Wistar rats with average weight of 200g were divided into 5 treatment groups of 10 rats per group.... more
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    • Garcinia kola
Withania somnifera of the family Solanaceae has been considered as an important herb in the traditional Ayurvedic and in the indigenous medical system in Bangladesh for its use in the prevention of different central nervous system (CNS)... more
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      Free RadicalsComplementary and Alternative MedicineFlavonoidsFree Radical
Context: Garcinia kola seeds are widely used in Congolese traditional medicine to treat uncomplicated malaria. While the ethanolic extract of these seeds (GK) is reputed for oral antimalarial activity, some of its constituents have shown... more
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      Traditional MedicineMedicinal PlantsMedicinal plants and natural productsMouse
The use of antibiotics as growth promoters in food animals has been banned due to the residual effects on final consumers which could lead to human health issues. The aim of the present study was to investigate the effects of two herbal... more
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      Garcinia kolaSerum biochemical markers
Phytochemical investigation of the methanol extract of the twigs of Garcinia staudtii yielded four new prenylated xanthones, staudtiixanthones AÀD (1-4), along with eleven known compounds. Their structures were determined by analysis of... more
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      Organic ChemistryCytokinesPharmacognosyStructural Analysis
A rapid, sensitive and simple reverse-phase high-performance liquid chromatography–electrospray ionization mass spectrometric method has been developed for the identification and quantification of two isomeric polyisoprenylated... more
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      Analytical ChemistryBiomedicalHPLCFruit
Ethnopharmacology relevance: Garcinia gardneriana (Planchon and Triana) Zappi (Clusiaceae) is popularly called "bacopari" in southern Brazil. The leaves of this plant are traditionally used to treat skin disorders. Aim of study: This... more
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      Complementary and Alternative MedicinePlant BiologyEthnopharmacologyMice
Citation: Ijomone OM, Nwoha PU, Olaibi OK, Obi AU, Alese MO. Neuroprotective Effects of Kolaviron, a Biflavonoid Complex of Garcinia kola, on Rats Hippocampus against Methamphetamine-Induced Neurotoxicity. Maced J Med Sci. 2012 Mar 15;... more
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    •   8  
      MacedonianHistologyHippocampusLearning and Memory
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full... more
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      GeneticsMicrobiologyTaxonomyMacromolecular X-Ray Crystallography
The methanol extract of Urtica crenulata stem was evaluated for its antinociceptive properties on the pain induced by acetic acid and formalin in Swiss albino mice. The methanol extract of U. crenulata at a dose of 1 g/kg produced an... more
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      Molecular BiologyAnimal BehaviorPainComplementary and Alternative Medicine
Four new prenylated depsidones, oliveridepsidones A-D, were isolated from the bark of Garcinia oliveri collected in Vietnam. Their structures were elucidated using mainly NMR techniques ( 1 H and 13 C NMR, HMQC, HMBC and NOE experiments).... more
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    •   7  
      Magnetic Resonance SpectroscopyAntioxidantsNmrGarcinia kola
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    •   6  
      Natural ProductsBiological SciencesCHEMICAL SCIENCESGarcinia kola
Six biflavonoids were isolated from G. madruno, one of which, 7''-O-(6''''-acetyl)-glucoside of morelloflavone, is a new compound identified on the basis of 1D, 2D NMR (HMQC and HMBC) spectroscopic methods and chemical evidence. The... more
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    •   6  
      Organic ChemistryAntioxidantsCopperLipid peroxidation
Ionizing radiation is one of the environmental factors that may contribute to reproductive dysfunction by a mechanism involving oxidative stress. We investigated the possible ameliorative effects of kolaviron (KV) (a biflavonoid from the... more
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      ReproductionOxidative StressFlavonoidsGamma Rays
The damaging effects of sunlight to the skin has triggered studies that involve the synthesis and extraction of organic compounds from natural sources that can absorb UV radiation, and studies on polyphenolic compounds with antioxidant... more
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      CytotoxicityPeroxidaseGlutathioneSkin
Introduction : The fruit extract of Garcinia atroviridis (G. atroviridis) contains hydroxycitric acid and flavonoids, which have been reported to have a hypolipidaemic property. This extract with solvent methanol was used to investigate... more
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      FruitNutritional StatusGarcinia kolaPlant extracts
A MeOH extract of Garcinia xanthochymus fruits was subjected to activity-guided fractionation, yielding two new benzophenones, guttiferone H (1) and gambogenone (2). Compound 1 contains a seven-membered ring attached to the... more
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      Natural ProductsPharmacognosyMedicinal PlantsCytotoxicity
A MeOH extract of Garcinia xanthochymus fruits was subjected to activity-guided fractionation, yielding two new benzophenones, guttiferone H (1) and gambogenone (2). Compound 1 contains a seven-membered ring attached to the... more
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      Natural ProductsPharmacognosyMedicinal PlantsCytotoxicity
In order to find the strategies to ensure the sustainable management of natural’s resources and especially woody plants in the Congo Basin, a study was carried out on the floristic diversity of woody plants and the structure of Garcinia... more
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    •   5  
      DiversityCameroonCytotoxicitySustainable forestry management
Hydroxycut, an herbal supplement not currently defined as a drug, is frequently sold over the counter to increase exercise performance, build muscles, and burn fat. The effects of 8 wk of hydroxycut-induced changes on blood lipid profile... more
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      LipidsEnvironmental SciencesTeaDietary Supplements
Phytochemical studies on the leaves and trunk bark of Garcinia cantleyana yielded five caged-xanthonoids including one tetra-and four tri-prenylated xanthones, cantleyanone A (1), 7-hydroxyforbesione (2) and cantleyanones B-D (4-6), as... more
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      PhytochemistryBiological SciencesCell lineCHEMICAL SCIENCES
: 912-916 912 Evaluation of the dust and methanol extracts of Garcinia kolae for the control of Callosobruchus maculatus (F.) and Sitophilus zeamais (Mots) Abstract: Insecticidal effects of different doses of the dust and methanol... more
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      TechnologyBiological SciencesMethanolBeetles
Pyrostegia venusta (Ker Gawl.) Miers, Bignoniaceae, is native to the Brazilian Cerrado and popularly known as "cipó-de-são-joão". In Brazilian folk medicine, the flowers of P. venusta are used as a general tonic and a treatment for... more
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      Nutrition and DieteticsImmunologyPainFolk Medicine
Natural products derived from plants provide a rich source for development of new anticancer drugs. Dulxanthone A was found to be an active cytotoxic component in Garcinia cowa by bioactivity-directed isolation. Studies to elucidate the... more
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      CancerMitochondriaApoptosisWestern blotting
We examined the in vitro effects of the benzophenone derivatives garcinol, isogarcinol, and xanthochymol on cell growth in four human leukemia cell lines. All of the compounds exhibited significant growth suppression due to apoptosis... more
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      Plant BiologyLeukemiaApoptosisCell line
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    •   13  
      Natural ProductsComplementary and Alternative MedicinePlant BiologyMedicinal Plants
In Brazilian folk medicine, the leaves of Garcinia brasiliensis are used to treat tumors, inflammation of the urinary tract and arthritis as well as to relieve pain. Nevertheless, scientific information regarding Garcinia brasiliensis is... more
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      Nutrition and DieteticsImmunologyPainFolk Medicine
A new compound, named banganxanthone C (=12-(1,1-dimethylprop-2-en-1-yl)-5,10-dihydroxy-9-methoxy-2-methyl-2-(4-methylpent-3-en-1-yl)-2H,6H-pyrano[3,2-b]xanthen-6-one; 4), together with five known compounds, were isolated from the leaves... more
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      ChemistryOrganic ChemistryApoptosisMedicine
The present study was undertaken to assess the neuroprotective effects of aqueous extract of Garcinia kola on neurotoxin administered malnourished mice. The study was carried out using thirty-two adult Malnourished mice which were... more
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    •   6  
      HippocampusCerebellumKey wordsNeurons
BACKGROUND Tuberculosis (TB) is an infectious disease of international health priority. The combination of anti-TB drugs (4-Tabs)- isoniazid (INH), rifampicin (RIF), pyrazinamide (PZA) and ethambutol (ETB) are effective in the management... more
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    •   18  
      Oxidative StressFlavonoidsMedicineAntioxidants
In order to find the strategies to ensure the sustainable management of natural’s resources and especially woody plants in the Congo Basin, a study was carried out on the floristic diversity of woody plants and the structure of Garcinia... more
    • by 
    •   5  
      DiversityCameroonCytotoxicitySustainable forestry management
In humans, many diseases are associated with the accumulation of free radicals. Antioxidants can scavenge free radicals and minimize their impact. Therefore, the search for naturally occurring antioxidants of plant origin is imperative.... more
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    •   17  
      Free RadicalsComplementary and Alternative MedicineFlavonoidsFree Radical
The damaging effects of sunlight to the skin has triggered studies that involve the synthesis and extraction of organic compounds from natural sources that can absorb UV radiation, and studies on polyphenolic compounds with antioxidant... more
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    •   12  
      CytotoxicityPeroxidaseGlutathioneSkin
Screening of eight Congolese medicinal plants showed that the CHCl 3 and MeOH extracts of Aframomum melegueta (PC 50 = 47.8 mg/mL and 13.8 mg/mL, respectively) and CHCl 3 extracts of Garcinia huillensis (PC 50 = 17.8 mg/mL) and Securidaca... more
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    •   7  
      Medicinal PlantsBiological SciencesPhytotherapyCHEMICAL SCIENCES