Axonal Protection by Tacrolimus with Inhibition of NFATc1 in TNF-Induced Optic Nerve Degeneration (Q92006668)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31087207%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

title

Axonal Protection by Tacrolimus with Inhibition of NFATc1 in TNF-Induced Optic Nerve Degeneration (English)

1 reference

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26 April 2020

1 reference

Chihiro Tsukahara

1

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26 April 2020

Kana Sase

2

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26 April 2020

Naoki Fujita

3

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26 April 2020

Hitoshi Takagi

4

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26 April 2020

Yasushi Kitaoka

5

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26 April 2020

publication date

13 May 2019

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26 April 2020

published in

Neurochemical Research

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26 April 2020

volume

44

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26 April 2020

issue

7

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26 April 2020

page(s)

1726-1735

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Ca2+, Astrocyte Activation and Calcineurin/NFAT Signaling in Age-Related Neurodegenerative Diseases

26 April 2020

cites work

1 reference

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Activation of the NFAT-Calcium Signaling Pathway in Human Lamina Cribrosa Cells in Glaucoma

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Involvement of mGluR I in EphB/ephrinB reverse signaling activation induced retinal ganglion cell apoptosis in a rat chronic hypertension model.

23 February 2021

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Axonal Protection by Ripasudil, a Rho Kinase Inhibitor, via Modulating Autophagy in TNF-Induced Optic Nerve Degeneration

23 February 2021

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Calcineurin/NFAT Signaling in Activated Astrocytes Drives Network Hyperexcitability in Aβ-Bearing Mice

23 February 2021

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Repair of Neurological Function in Response to FK506 Through CaN/NFATc1 Pathway Following Traumatic Brain Injury in Rats

23 February 2021

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Blockade of Astrocytic Calcineurin/NFAT Signaling Helps to Normalize Hippocampal Synaptic Function and Plasticity in a Rat Model of Traumatic Brain Injury.

23 February 2021

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NFAT2 Isoforms Differentially Regulate Gene Expression, Cell Death, and Transformation through Alternative N-Terminal Domains.

23 February 2021

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Attenuation of microglial activation in a mouse model of Alzheimer's disease via NFAT inhibition

23 February 2021

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NFATc1 deficiency in T cells protects mice from experimental autoimmune encephalomyelitis.

23 February 2021

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NFATc1 activity regulates the expression of myocilin induced by dexamethasone

23 February 2021

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The transcription factor NFAT1 induces apoptosis through cooperation with Ras/Raf/MEK/ERK pathway and upregulation of TNF-α expression

23 February 2021

1 reference

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Axonal protection via modulation of the amyloidogenic pathway in tumor necrosis factor-induced optic neuropathy.

23 February 2021

1 reference

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Neurodegenerative and Inflammatory Pathway Components Linked to TNF-α/TNFR1 Signaling in the Glaucomatous Human Retina

23 February 2021

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Response of transcription factor NFATc3 to excitotoxic and traumatic brain insults: identification of a subpopulation of reactive astrocytes.

23 February 2021

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Tumor necrosis factor-alpha concentrations in the aqueous humor of patients with glaucoma

23 February 2021

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TNF-alpha signaling in glaucomatous neurodegeneration

23 February 2021

1 reference

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Mechanical lesion activates newly identified NFATc1 in primary astrocytes: implication of ATP and purinergic receptors.

23 February 2021

1 reference

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Deafferentation-induced activation of NFAT (nuclear factor of activated T-cells) in cochlear nucleus neurons during a developmental critical period: a role for NFATc4-dependent apoptosis in the CNS

23 February 2021

1 reference

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Calcineurin in reactive astrocytes plays a key role in the interplay between proinflammatory and anti-inflammatory signals

23 February 2021

1 reference

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Constitutively active calcineurin mediates delayed neuronal death through Fas-ligand expression via activation of NFAT and FKHR transcriptional activities in mouse brain ischemia

23 February 2021

1 reference

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TNF-alpha-induced optic nerve degeneration and nuclear factor-kappaB p65.

23 February 2021

1 reference

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Calcium-dependent expression of TNF-alpha in neural cells is mediated by the calcineurin/NFAT pathway

23 February 2021

1 reference

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Calcineurin cleavage is triggered by elevated intraocular pressure, and calcineurin inhibition blocks retinal ganglion cell death in experimental glaucoma

23 February 2021

1 reference

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A novel mechanism of FK506-mediated neuroprotection: downregulation of cytokine expression in glial cells.

23 February 2021

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Critical role of calpain-mediated cleavage of calcineurin in excitotoxic neurodegeneration.

23 February 2021

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Transcriptional regulation by calcium, calcineurin, and NFAT

23 February 2021

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Differential effects of immunophilin-ligands (FK506 and V-10,367) on survival and regeneration of rat retinal ganglion cells in vitro and after optic nerve crush in vivo

23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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Regulation of the calmodulin-stimulated protein phosphatase, calcineurin

23 February 2021

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Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

23 February 2021

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Distinct Cellular Expression of Calcineurin Aα and Aβ in Rat Brain

23 February 2021

1 reference

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10.1007/S11064-019-02804-6

23 February 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31087207%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31087207%20AND%20SRC:MED&resulttype=core&format=json

26 April 2020

PubMed publication ID

31087207

1 reference