A novel mechanism of FK506-mediated neuroprotection: downregulation of cytokine expression in glial cells. (Q45076802)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15390105%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

title

A novel mechanism of FK506-mediated neuroprotection: downregulation of cytokine expression in glial cells (English)

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2 January 2020

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1

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Bożena Kamińska-Kaczmarek

2 January 2020

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15390105%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

author name string

Malgorzata Zawadzka

series ordinal

1

1 reference

9 December 2017

Bozena Kaminska

series ordinal

2

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9 December 2017

publication date

1 January 2005

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15390105%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15390105%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

volume

49

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2 January 2020

issue

1

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2 January 2020

page(s)

36-51

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Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats

2 January 2020

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Neuroprotective effect of immunosuppressant FK506 in transient focal ischemia in rat: therapeutic time window for FK506 in transient focal ischemia

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Changes in peptidyl-prolyl cis/trans isomerase activity and FK506 binding protein expression following neuroprotection by FK506 in the ischemic rat brain

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Neuroprotective actions of FK506 in experimental stroke: in vivo evidence against an antiexcitotoxic mechanism.

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The effects of post-ischemic hypothermia on the neuronal injury and brain metabolism after forebrain ischemia in the rat

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Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

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Pathobiology of ischaemic stroke: an integrated view

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Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death.

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Reactive microglia in cerebral ischaemia: an early mediator of tissue damage?

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Peptidyl-prolyl cis-trans isomerases, a superfamily of ubiquitous folding catalysts

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Elevation of basal intracellular calcium as a central element in the activation of brain macrophages (microglia): suppression of receptor-evoked calcium signaling and control of release function.

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Cyclosporin A and its nonimmunosuppressive analogue N-Me-Val-4-cyclosporin A mitigate glucose/oxygen deprivation-induced damage to rat cultured hippocampal neurons

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7 January 2021

The immunophilin-ligands FK506 and V-10,367 mediate neuroprotection by the heat shock response

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7 January 2021

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7 January 2021

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

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7 January 2021

Cyclosporin A, an immunosuppressive drug, induces programmed cell death in rat C6 glioma cells by a mechanism that involves the AP-1 transcription factor.

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7 January 2021

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7 January 2021

Changes of the trans-activating potential of AP-1 transcription factor during cyclosporin A-induced apoptosis of glioma cells are mediated by phosphorylation and alterations of AP-1 composition

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7 January 2021

Cyclosporin A-sensitive signaling pathway involving calcineurin regulates survival of reactive astrocytes

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7 January 2021

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Reduced Ischemic Brain Injury in Interleukin-1β Converting Enzyme—Deficient Mice

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7 January 2021

Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia

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7 January 2021

Cyclosporin A protects against ischemia-reperfusion injury in the brain

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7 January 2021

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7 January 2021

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7 January 2021

Calcineurin inhibitor, FK506, prevents reduction in the binding capacity of cyclic AMP-dependent protein kinase in ischemic gerbil brain

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Identifiers

DOI

10.1002/GLIA.20092

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15390105%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference