Constitutively active calcineurin mediates delayed neuronal death through Fas-ligand expression via activation of NFAT and FKHR transcriptional activities in mouse brain ischemia (Q48091707)

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scientific article published on 30 April 2007

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English	Constitutively active calcineurin mediates delayed neuronal death through Fas-ligand expression via activation of NFAT and FKHR transcriptional activities in mouse brain ischemia	scientific article published on 30 April 2007

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scholarly article

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Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/17662023

Constitutively active calcineurin mediates delayed neuronal death through Fas-ligand expression via activation of NFAT and FKHR transcriptional activities in mouse brain ischemia (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/17662023

author name string

Norifumi Shioda

1

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Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/17662023

Feng Han

2

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Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/17662023

Shigeki Moriguchi

3

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/17662023

Kohji Fukunaga

4

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Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/17662023

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publication date

30 April 2007

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Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/17662023

Journal of Neurochemistry

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Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/17662023

102

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Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/17662023

5

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Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/17662023

1506-1517

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/17662023

High level calcineurin activity predisposes neuronal cells to apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Regulation of cell death protease caspase-9 by phosphorylation

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

NFAT signaling: choreographing the social lives of cells

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

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https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Activation of ERK and Akt signaling in focal cerebral ischemia: modulation by TGF-alpha and involvement of NMDA receptor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Akt is a molecular target for signal transduction therapy in brain ischemic insult

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Immunohistochemical localization of Ca2+/calmodulin-dependent protein kinase II in rat brain and various tissues

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Transcriptional regulation of neuronal genes and its effect on neural functions: expression and function of forkhead transcription factors in neurons

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

TR3 death receptor expression in the normal and ischaemic brain.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Neuroprotective effect of postischemic administration of sodium orthovanadate in rats with transient middle cerebral artery occlusion

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Therapeutic time window and dose dependence of neuroprotective effects of sodium orthovanadate following transient middle cerebral artery occlusion in rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Up-regulation of endothelial nitric oxide synthase via phosphatidylinositol 3-kinase pathway contributes to ischemic tolerance in the CA1 subfield of gerbil hippocampus

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

The post-ischemic administration of 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate (DY-9760e), a novel calmodulin antagonist, prevents delayed neuronal death in ger

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Transcriptional regulation by calcium, calcineurin, and NFAT

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Transcriptional Regulation of the Human FasL Promoter-Enhancer Region

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Calcineurin/NFAT-induced up-regulation of the Fas ligand/Fas death pathway is involved in methamphetamine-induced neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Fas (CD95) may mediate delayed cell death in hippocampal CA1 sector after global cerebral ischemia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Neuroprotective effect of sodium orthovanadate on delayed neuronal death after transient forebrain ischemia in gerbil hippocampus

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Decreased akt activity is associated with activation of forkhead transcription factor after transient forebrain ischemia in gerbil hippocampus

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Regulation of the calmodulin-stimulated protein phosphatase, calcineurin

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Decreased calcineurin and increased phosphothreonine-DARPP-32 in the striatum of rats behaviorally sensitized to methamphetamine

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Truncation and activation of calcineurin A by calpain I in Alzheimer disease brain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Regional and Temporal Alterations in Ca2+/Calmodulin‐Dependent Protein Kinase II and Calcineurin in the Hippocampus of Rat Brain After Transient Forebrain Ischemia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

The Fas death factor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Fas antigen expression in brains of patients with Alzheimer-type dementia.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Evidence of phosphorylation of Akt and neuronal survival after transient focal cerebral ischemia in mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Calcium movement in ischemia-tolerant hippocampal CA1 neurons after transient forebrain ischemia in gerbils

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Calcium regulation of calcineurin phosphatase activity by its B subunit and calmodulin. Role of the autoinhibitory domain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Substrate selectivity and sensitivity to inhibition by FK506 and cyclosporin A of calcineurin heterodimers composed of the alpha or beta catalytic subunit

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Transcription factors of the NFAT family: regulation and function

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Requirement of nuclear factor of activated T-cells in calcineurin-mediated cardiomyocyte hypertrophy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

A dynamic assembly of diverse transcription factors integrates activation and cell-type information for interleukin 2 gene regulation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Calcineurin functions in Ca(2+)-activated cell death in mammalian cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Role of kinases and the phosphatase calcineurin in the nuclear shuttling of transcription factor NF-AT4.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Generation of constitutively active calcineurin by calpain contributes to delayed neuronal death following mouse brain ischemia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Blockade of N -Methyl-D-Aspartate Receptors May Protect Against Ischemic Damage in the Brain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Differential neuroprotection by cyclosporin A and FK506 following ischemia corresponds with differing abilities to inhibit calcineurin and the mitochondrial permeability transition

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Activation of Akt/protein kinase B contributes to induction of ischemic tolerance in the CA1 subfield of gerbil hippocampus

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

NF-AT activation requires suppression of Crm1-dependent export by calcineurin

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04600.X

21 January 2018

Identifiers

10.1111/J.1471-4159.2007.04600.X

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/17662023

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 February 2018

http://europepmc.org/abstract/MED/17662023

ResearchGate publication ID

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