Critical role of lysine 134 methylation on histone H2AX for γ-H2AX production and DNA repair. (Q42935227)

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24 February 2020

title

Critical role of lysine 134 methylation on histone H2AX for γ-H2AX production and DNA repair (English)

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24 February 2020

3

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5

Thomas Jenuwein

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24 February 2020

1

Kenbun Sone

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24 February 2020

author name string

Lianhua Piao

2

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24 February 2020

Koji Ueda

4

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24 February 2020

Yusuke Nakamura

6

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24 February 2020

Ryuji Hamamoto

7

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24 February 2020

language of work or name

English

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publication date

9 December 2014

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24 February 2020

published in

Nature Communications

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volume

5

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24 February 2020

page(s)

5691

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Creative Commons Attribution 4.0 International

24 February 2020

copyright license

start time

1 December 2014

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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RB1 methylation by SMYD2 enhances cell cycle progression through an increase of RB1 phosphorylation

27 May 2018

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The JmjC domain-containing histone demethylase KDM3A is a positive regulator of the G1/S transition in cancer cells via transcriptional regulation of the HOXA1 gene

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27 May 2018

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27 May 2018

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Monoubiquitination of H2AX Protein Regulates DNA Damage Response Signaling

27 May 2018

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Minichromosome Maintenance Protein 7 is a potential therapeutic target in human cancer and a novel prognostic marker of non-small cell lung cancer

27 May 2018

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27 May 2018

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Histone γH2AX and Poly(ADP-Ribose) as Clinical Pharmacodynamic Biomarkers

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27 May 2018

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Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers

27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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New nomenclature for chromatin-modifying enzymes

27 May 2018

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RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

27 May 2018

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DNA strand break repair and human genetic disease

27 May 2018

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GammaH2AX in cancer cells: a potential biomarker for cancer diagnostics, prediction and recurrence

27 May 2018

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gamma-H2AX as a therapeutic target for improving the efficacy of radiation therapy.

27 May 2018

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Enhanced SMYD3 expression is essential for the growth of breast cancer cells

27 May 2018

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Cellular processing of platinum anticancer drugs

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DNA repair: the importance of phosphorylating histone H2AX.

27 May 2018

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Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM

27 May 2018

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Histone modifications and DNA double-strand break repair

27 May 2018

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H2AX: the histone guardian of the genome

27 May 2018

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SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells

27 May 2018

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27 May 2018

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Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks

27 May 2018

1 reference

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Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX

27 May 2018

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Genomic instability in mice lacking histone H2AX

27 May 2018

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Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase

27 May 2018

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Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability

27 May 2018

1 reference

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27 May 2018

1 reference

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DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

27 May 2018

1 reference

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27 May 2018

1 reference

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Deregulation of the histone demethylase JMJD2A is involved in human carcinogenesis through regulation of the G(1)/S transition

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268694

Demethylation of RB regulator MYPT1 by histone demethylase LSD1 promotes cell cycle progression in cancer cells.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268694

Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases

16 August 2018

1 reference

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Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268694

Expression of γ-H2AX in endometrial carcinomas: an immunohistochemical study with p53

16 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25487737

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Histone H2AX Phosphorylation as a Predictor of Radiosensitivity and Target for Radiotherapy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25487737

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25487737

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS6691

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25487737%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

0 references

1 reference

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24 February 2020

PubMed publication ID

25487737

1 reference