3-D DNA methylation phenotypes correlate with cytotoxicity levels in prostate and liver cancer cell models (Q34581149)

3 August 2017

title

3-D DNA methylation phenotypes correlate with cytotoxicity levels in prostate and liver cancer cell models (English)

1 reference

3 August 2017

0 references

0 references

1 reference

Daniel J Weisenberger

series ordinal

4

object named as

Daniel J Weisenberger

1 reference

3 August 2017

1

Arkadiusz Gertych

1 reference

3 August 2017

Jin Ho Oh

2

1 reference

3 August 2017

Kolja A Wawrowsky

series ordinal

3

1 reference

3 August 2017

Jian Tajbakhsh

series ordinal

5

1 reference

3 August 2017

publication date

11 February 2013

1 reference

BMC pharmacology & toxicology

3 August 2017

published in

1 reference

3 August 2017

volume

14

1 reference

3 August 2017

page(s)

11

1 reference

Genome-wide mapping of nucleosome positioning and DNA methylation within individual DNA molecules

3 August 2017

cites work

1 reference

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GSTP1 DNA methylation and expression status is indicative of 5-aza-2'-deoxycytidine efficacy in human prostate cancer cells

7 July 2018

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7 July 2018

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Azacytidine and Decitabine Induce Gene-Specific and Non-Random DNA Demethylation in Human Cancer Cell Lines

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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The effect of cell cycle synchronization on tumor sensitivity to reovirus oncolysis

7 July 2018

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7 July 2018

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Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine

7 July 2018

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Chromatin remodeling is required for gene reactivation after decitabine-mediated DNA hypomethylation.

7 July 2018

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Higher-order genome organization in human disease

7 July 2018

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DNA hypomethylation in cancer cells

7 July 2018

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Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact

7 July 2018

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5-azacytidine treatment reorganizes genomic histone modification patterns

7 July 2018

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Principles and challenges of genomewide DNA methylation analysis

7 July 2018

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Chromatin profiling by directly sequencing small quantities of immunoprecipitated DNA.

7 July 2018

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An oestrogen-receptor-α-bound human chromatin interactome

7 July 2018

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Comprehensive mapping of long-range interactions reveals folding principles of the human genome

7 July 2018

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Epigenetic DNA-(cytosine-5-carbon) modifications: 5-aza-2'-deoxycytidine and DNA-demethylation

7 July 2018

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Epigenetic side-effects of common pharmaceuticals: a potential new field in medicine and pharmacology

7 July 2018

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DNA (Cytosine-C5) methyltransferase inhibition by oligodeoxyribonucleotides containing 2-(1H)-pyrimidinone (zebularine aglycon) at the enzymatic target site

7 July 2018

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Automated quantification of DNA demethylation effects in cells via 3D mapping of nuclear signatures and population homogeneity assessment

7 July 2018

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Effects of a novel DNA methyltransferase inhibitor zebularine on human breast cancer cells

7 July 2018

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Hunting for the 5th base: Techniques for analyzing DNA methylation

7 July 2018

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Heterochromatic genome stability requires regulators of histone H3 K9 methylation

7 July 2018

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7 July 2018

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Alterations of constitutive pericentromeric heterochromatin in lymphocytes of cancer patients and lymphocytes exposed to 5-azacytidine is associated with DNA-hypomethylation.

7 July 2018

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Azacytidine causes complex DNA methylation responses in myeloid leukemia

7 July 2018

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Epigenetic regulation of telomeres in human cancer.

7 July 2018

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Modes of action of the DNA methyltransferase inhibitors azacytidine and decitabine.

7 July 2018

1 reference

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Epigenetic regulation of heterochromatic DNA stability

7 July 2018

1 reference

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Drug-induced senescence bystander proliferation in prostate cancer cells in vitro and in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3598242

7 July 2018

Epigenetics in cancer

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3598242

Demethylation of (Cytosine-5-C-methyl) DNA and regulation of transcription in the epigenetic pathways of cancer development.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3598242

Role of nucleosomal occupancy in the epigenetic silencing of the MLH1 CpG island.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3598242

Nuclear organization of the genome and the potential for gene regulation

7 July 2018

1 reference

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DNA methylation affects nuclear organization, histone modifications, and linker histone binding but not chromatin compaction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3598242

Epigenetic combination therapy as a tumor-selective treatment approach for hepatocellular carcinoma.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3598242

The epigenomics of cancer

7 July 2018

1 reference

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Zebularine inhibits human acute myeloid leukemia cell growth in vitro in association with p15INK4B demethylation and reexpression.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3598242

Epigenetic control of nuclear architecture

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3598242

Chromosome Conformation Capture Carbon Copy (5C): a massively parallel solution for mapping interactions between genomic elements

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3598242

Epigenetic tête-à-tête: the bilateral relationship between chromatin modifications and DNA methylation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3598242

Cellular imaging in drug discovery

7 July 2018

1 reference

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Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines.

7 July 2018

1 reference

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Epigenetic therapy of cancer: past, present and future

7 July 2018

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Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy

7 July 2018

1 reference

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Analysis of repetitive element DNA methylation by MethyLight

7 July 2018

1 reference

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Footprinting of mammalian promoters: use of a CpG DNA methyltransferase revealing nucleosome positions at a single molecule level

7 July 2018

1 reference

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The identification of senescence-specific genes during the induction of senescence in prostate cancer cells

7 July 2018

1 reference

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Enhancement of in vitro and in vivo tumor cell radiosensitivity by the DNA methylation inhibitor zebularine

7 July 2018

1 reference

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5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal

7 July 2018

1 reference

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Mammalian cells lack checkpoints for tetraploidy, aberrant centrosome number, and cytokinesis failure

7 July 2018

1 reference

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Zebularine: a new drug for epigenetic therapy

7 July 2018

1 reference

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Role of the DNA methyltransferase variant DNMT3b3 in DNA methylation.

7 July 2018

1 reference

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Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells

7 July 2018

1 reference

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5-aza-2'-deoxycytidine activates the p53/p21Waf1/Cip1 pathway to inhibit cell proliferation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3598242

Gene silencing in cancer in association with promoter hypermethylation

7 July 2018

1 reference

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Hypomethylation: One Side of a Larger Picture

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3598242

Induction of Tumors in Mice by Genomic Hypomethylation

7 July 2018

1 reference

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Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

7 July 2018

1 reference

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5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy

7 July 2018

1 reference

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DNA methylation in cancer: too much, but also too little

7 July 2018

1 reference

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Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

7 July 2018

1 reference

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Stem-loop binding protein, the protein that binds the 3' end of histone mRNA, is cell cycle regulated by both translational and posttranslational mechanisms

7 July 2018

1 reference

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Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

7 July 2018

1 reference

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Roles of cell division and gene transcription in the methylation of CpG islands.

7 July 2018

1 reference

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Alu repeats and human disease

7 July 2018

1 reference

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Annexin V-Affinity assay: A review on an apoptosis detection system based on phosphatidylserine exposure

7 July 2018

1 reference

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Creation of genomic methylation patterns

7 July 2018

1 reference

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The effects of 5-azacytidine and 5-azadeoxycytidine on chromosome structure and function: implications for methylation-associated cellular processes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3598242

Amount and distribution of 5-methylcytosine in human DNA from different types of tissues of cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3598242

The 5-methylcytosine content of DNA from human tumors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3598242

Covalent bond formation between a DNA-cytosine methyltransferase and DNA containing 5-azacytosine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3598242

Hypomethylation distinguishes genes of some human cancers from their normal counterparts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3598242

CpG islands in vertebrate genomes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3598242

Inhibition of DNA methylation and reactivation of silenced genes by zebularine

7 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F2050-6511-14-11

The novel DNA methylation inhibitor zebularine is effective against the development of murine T-cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2050-6511-14-11

The architecture of interphase chromosomes and gene positioning are altered by changes in DNA methylation and histone acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2050-6511-14-11

Heterochromatin, HP1 and methylation at lysine 9 of histone H3 in animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2050-6511-14-11

Hypomethylation and apoptosis in 5-azacytidine-treated myeloid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2050-6511-14-11

DNA motifs associated with aberrant CpG island methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2050-6511-14-11

The length of CpG islands is associated with the distribution of Alu and L1 retroelements

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F2050-6511-14-11

Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3598242

DNA modification mechanisms and gene activity during development

27 October 2018

1 reference

12 December 2020

Cytological evidence for 5-azacytidine-induced demethylation of the heterochromatic regions of human chromosomes

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12 December 2020

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12 December 2020

Cytomics for discovering drugs

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12 December 2020

DNA hypomethylation, cancer, the immunodeficiency, centromeric region instability, facial anomalies syndrome and chromosomal rearrangements

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12 December 2020

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12 December 2020

Identifiers

DOI

10.1186/2050-6511-14-11

1 reference

Dimensions Publication ID

3 August 2017

0 references

1 reference

3 August 2017

1 reference