Wt1 in the kidney--a tale in mouse models. (Q38163312)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24240471%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Wt1 in the kidney--a tale in mouse models (English)

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1 March 2020

2

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1 March 2020

author name string

Derya Deniz Ozdemir

series ordinal

1

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1 March 2020

publication date

18 November 2013

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24240471%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24240471%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

volume

29

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24240471%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

issue

4

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1 March 2020

page(s)

687-693

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24240471%20AND%20SRC:MED&resulttype=core&format=json

Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping

1 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

The candidate Wilms' tumour gene is involved in genitourinary development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

The expression of the Wilms' tumour gene, WT1, in the developing mammalian embryo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

WT1 in disease: shifting the epithelial-mesenchymal balance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

The many facets of the Wilms' tumour gene, WT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

Transcriptional regulation by WT1 in development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

A wt1-controlled chromatin switching mechanism underpins tissue-specific wnt4 activation and repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

Subnuclear localization of WT1 in splicing or transcription factor domains is regulated by alternative splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

WT1 interacts with the splicing factor U2AF65 in an isoform-dependent manner and can be incorporated into spliceosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

Expression in Xenopus oocytes shows that WT1 binds transcripts in vivo, with a central role for zinc finger one.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

The predominant WT1 isoform (+KTS) encodes a DNA-binding protein targeting the planar cell polarity gene Scribble in renal podocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

The Wilms' tumour protein (WT1) shuttles between nucleus and cytoplasm and is present in functional polysomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

The Wilms’ tumour suppressor protein, WT1, undergoes CRM1‐independent nucleocytoplasmic shuttling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

Actin: a novel interaction partner of WT1 influencing its cell dynamic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

YAC transgenic analysis reveals Wilms' tumour 1 gene activity in the proliferating coelomic epithelium, developing diaphragm and limb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

Patterning a complex organ: branching morphogenesis and nephron segmentation in kidney development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

WT-1 is required for early kidney development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

The Wilms' tumor gene Wt1 is required for normal development of the retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

A splice variant of the Wilms' tumour suppressor Wt1 is required for normal development of the olfactory system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

The Wilms tumor suppressor gene wt1 is required for development of the spleen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

The genetics of Wilms' tumor--a case of disrupted development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

Wnt-4 regulation by the Wilms' tumour suppressor gene, WT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

Development of an siRNA-based method for repressing specific genes in renal organ culture and its use to show that the Wt1 tumour suppressor is required for nephron differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

Genomic characterization of Wilms' tumor suppressor 1 targets in nephron progenitor cells during kidney development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

Tissue-specific expression of cre recombinase from the Pax8 locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

The Wt1+/R394W mouse displays glomerulosclerosis and early-onset renal failure characteristic of human Denys-Drash syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

A zinc finger truncation of murine WT1 results in the characteristic urogenital abnormalities of Denys-Drash syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

Effects on kidney disease, fertility and development in mice inheriting a protein-truncating Denys-Drash syndrome allele (Wt1tmT396).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

WT1 is a key regulator of podocyte function: reduced expression levels cause crescentic glomerulonephritis and mesangial sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

The wt1-heterozygous mouse; a model to study the development of glomerular sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

A mutant form of the Wilms' tumor suppressor gene WT1 observed in Denys-Drash syndrome interferes with glomerular capillary development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

Acute multiple organ failure in adult mice deleted for the developmental regulator Wt1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

Donor splice-site mutations in WT1 are responsible for Frasier syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

Two splice variants of the Wilms' tumor 1 gene have distinct functions during sex determination and nephron formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

A mammal-specific exon of WT1 is not required for development or fertility

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

Mice lacking the 68-amino-acid, mammal-specific N-terminal extension of WT1 develop normally and are fertile

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

Par4 is a coactivator for a splice isoform-specific transcriptional activation domain in WT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

The Wilms' tumor gene WT1-GFP knock-in mouse reveals the dynamic regulation of WT1 expression in normal and leukemic hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

Genomic imprinting at the WT1 gene involves a novel coding transcript (AWT1) that shows deregulation in Wilms' tumours.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-013-2673-7

Frequent association of beta-catenin and WT1 mutations in Wilms tumors.

21 January 2018

1 reference

12 December 2020

YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesis

1 reference

12 December 2020

Mutational activation of the beta-catenin proto-oncogene is a common event in the development of Wilms' tumors

1 reference

12 December 2020

Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney

1 reference

12 December 2020

Twenty-four new cases of WT1 germline mutations and review of the literature: genotype/phenotype correlations for Wilms tumor development

1 reference

12 December 2020