The many facets of the Wilms' tumour gene, WT1 (Q28264516)

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30 December 2019

review article

1 reference

title

The many facets of the Wilms' tumour gene, WT1 (English)

2 references

9 April 2017

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30 December 2019

1

1 reference

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30 December 2019

author name string

Nicholas D Hastie

series ordinal

2

1 reference

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30 December 2019

language of work or name

English

0 references

publication date

1 October 2006

1 reference

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30 December 2019

published in

Human Molecular Genetics

2 references

9 April 2017

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30 December 2019

volume

15 Spec No 2

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30 December 2019

issue

Review Issue 2

1 reference

9 April 2017

page(s)

R196-201

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An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor

30 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

Genomic imprinting at the WT1 gene involves a novel coding transcript (AWT1) that shows deregulation in Wilms' tumours.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

Two splice variants of the Wilms' tumor 1 gene have distinct functions during sex determination and nephron formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

Life, sex, and WT1 isoforms--three amino acids can make all the difference

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

A splice variant of the Wilms' tumour suppressor Wt1 is required for normal development of the olfactory system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

A mammal-specific exon of WT1 is not required for development or fertility

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

Mice lacking the 68-amino-acid, mammal-specific N-terminal extension of WT1 develop normally and are fertile

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

Transcriptional regulation by WT1 in development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

The Wilms tumor suppressor WT1 encodes a transcriptional activator of amphiregulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

The receptor tyrosine kinase regulator Sprouty1 is a target of the tumor suppressor WT1 and important for kidney development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

Coronary vessel development requires activation of the TrkB neurotrophin receptor by the Wilms' tumor transcription factor Wt1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

The major podocyte protein nephrin is transcriptionally activated by the Wilms' tumor suppressor WT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

Intermediate filament protein nestin is expressed in developing kidney and heart and might be regulated by the Wilms' tumor suppressor Wt1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

The Wilms' tumor suppressor Wt1 encodes a transcriptional activator of the class IV POU-domain factor Pou4f2 (Brn-3b)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

BASP1 is a transcriptional cosuppressor for the Wilms' tumor suppressor protein WT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

A WT1 co-regulator controls podocyte phenotype by shuttling between adhesion structures and nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

Subnuclear localization of WT1 in splicing or transcription factor domains is regulated by alternative splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

WT1 interacts with the splicing factor U2AF65 in an isoform-dependent manner and can be incorporated into spliceosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

Expression in Xenopus oocytes shows that WT1 binds transcripts in vivo, with a central role for zinc finger one.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

The Wilms' tumour protein (WT1) shuttles between nucleus and cytoplasm and is present in functional polysomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

The Wilms' tumor 1 (WT1) gene (+KTS isoform) functions with a CTE to enhance translation from an unspliced RNA with a retained intron

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

WT-1 is required for early kidney development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

Development of an siRNA-based method for repressing specific genes in renal organ culture and its use to show that the Wt1 tumour suppressor is required for nephron differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

The genetics of Wilms' tumor--a case of disrupted development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

Wnt-4 regulation by the Wilms' tumour suppressor gene, WT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

Tissue-specific RNAi reveals that WT1 expression in nurse cells controls germ cell survival and spermatogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

YAC transgenic analysis reveals Wilms' tumour 1 gene activity in the proliferating coelomic epithelium, developing diaphragm and limb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

WT1 is a tumor-associated antigen in colon cancer that can be recognized by in vitro stimulated cytotoxic T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

Upregulation of Wilms' tumor gene 1 (WT1) in desmoid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

Overexpression of the Wilms' tumor gene W T1 in primary astrocytic tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

HER2/neu increases the expression of Wilms' Tumor 1 (WT1) protein to stimulate S-phase proliferation and inhibit apoptosis in breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

Induction of WT1 (Wilms' tumor gene)-specific cytotoxic T lymphocytes by WT1 peptide vaccine and the resultant cancer regression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

Stabilization of beta-catenin in the mouse zygote leads to premature epithelial-mesenchymal transition in the epiblast

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

Beta-catenin is required for endothelial-mesenchymal transformation during heart cushion development in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

Murine Denys-Drash syndrome: evidence of podocyte de-differentiation and systemic mediation of glomerulosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDL196

21 January 2018

Identifiers

DOI

10.1093/HMG/DDL196

3 references

9 April 2017

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16987884%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017