Gafa6w0sr MITOSIS

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CELLULAR

REPRODUCTION
Prepared by: Ms. Ma. Filipina Q. Apid, LPT
What changes did you notice when you were
young and now that you are a teenager?
What happens to our wound after
a few days or weeks have
passed?
CELL DIVISION
o production of new cells to bring about growth;

o replacement of damaged cells in the wounded body parts;


and
o production of new generation of individuals among some
group of organisms
CELL DIVISION
Two kinds:

MITOSIS MEIOSIS
It takes place in our body cells It takes place in the ovaries and testes of
animals, including humans.
(somatic cells)
It is responsible for the formation of gametes or sex-
cells
RUDOLF VIRCHOW
• German pathologist in 1858
• In this process, one cell divides and
becomes two.
• The process of cell division repeated
over and over in a process called
CELL CYCLE.
CELL CYCLE DIAGRAM
2 main stages of cell cycle:

INTERPHASE
CELL DIVISION
CELL CYCLE DIAGRAM
2 main stages of cell cycle:
INTERPHASE
• It takes the longest period in
the cycle.
• In a 24-hour cell cycle, 23
hours is spent for interphase.
• It is described as the resting
stage.
CELL CYCLE DIAGRAM
INTERPHASE
G1 – “gap phase 1”
the cell grows physically larger, copies organelles,
and makes the molecular building blocks it will
need in later steps
S phase – “synthesis phase”
the cell synthesizes a complete copy of the DNA in
its nucleus
G2– “gap phase 2”
the cell grows more, makes proteins and organelles,
and begins to reorganize its contents in preparation
for mitosis
Packing for the move…

When cell is not dividing…


● DNA molecules in extended,
uncondensed form = chromatin
● Cell can only replicate and transcribe DNA when in
extended state.

When cell is preparing for division…


● DNA molecules condense to form
chromosomes prior to division.
CELL CYCLE DIAGRAM
2 main stages of cell cycle:

CELL DIVISION (M phase)


Stages of Mitosis
• Prophase
• Metaphase
• Anaphase
• Telophase
PROPHASE
telomere
Prophase is characterized by four events: chromatid

1. Chromosomes condense and are more


visible.
2. The nuclear membrane (envelope) centromere

disappears.
3. Centrioles have separated and taken
positions on the opposite poles of the cell.
4. Spindle fibers form and radiate toward the
center of the cell.
telomere

Condensed, duplicated chromosome


chromatin nucleus
condensing
chromosomes
PROPHASE
nucleolus

centrioles
METAPHASE
centrioles
Metaphase (the shortest phase of
mitosis) is characterized by two chromosomes

events:
spindle fibers
1. Chromosomes line up across
the middle of the cell.
2. Spindle fibers connect the
centromere of each sister
chromatid to the poles of the
cell.
ANAPHASE
Anaphase is characterized by three
events:

1. Centromeres that join the sister


chromatids split.
2. Sister chromatids separate
becoming individual
chromosomes.
3. Separated chromatids move to
opposite poles of the cell.
TELOPHASE
Telophase (the last phase of mitosis)
consists of four events:
1. Chromosomes (each consisting
of a single chromatid) uncoil.
2. A nuclear envelope forms around
the chromosomes at each pole of
the cell.
3. Spindle fibers break down and
dissolve.
4. Cytokinesis begins.
Cytokinesis
•Cytokinesis is the division of the cytoplasm into two
individual cells.
•The process of cytokinesis differs somewhat in plant
and animal cells.
•In animal cells the cell membrane forms a cleavage
furrow that eventually pinches the cell into two nearly
equal parts, each part containing its own nucleus and
cytoplasmic organelles.
Performance Task #1: MITOSIS MODEL

Using any available materials on your home, make a model that


shows the stages of mitosis. Do not forget to label each stage.
Use of recyclable materials is highly encouraged.

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