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    Maulidya Silviana
    This document contains the results of an analytical chemistry practicum group measuring the concentrations of paracetamol and salicylamide in samples. It includes: 1. The concentrations of stock standard solutions and working standard solutions of paracetamol and salicylamide that were prepared. 2. Regression analyses that were performed to determine the relationships between concentration and absorbance of the working standard solutions. 3. Calculations that were carried out to determine the concentrations of paracetamol and salicylamide in an unknown sample based on its measured absorbance values. 4. The determined concentrations of paracetamol and salicylamide in the unknown sample were 11.19 ppm

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    Kelompok Kfa

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    This document contains the results of an analytical chemistry practicum group measuring the concentrations of paracetamol and salicylamide in samples. It includes: 1. The concentrations of stock standard solutions and working standard solutions of paracetamol and salicylamide that were prepared. 2. Regression analyses that were performed to determine the relationships between concentration and absorbance of the working standard solutions. 3. Calculations that were carried out to determine the concentrations of paracetamol and salicylamide in an unknown sample based on its measured absorbance values. 4. The determined concentrations of paracetamol and salicylamide in the unknown sample were 11.19 ppm

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    KIMIA FARMASI ANALISIS

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    KELOMPOK KFA

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    This document contains the results of an analytical chemistry practicum group measuring the concentrations of paracetamol and salicylamide in samples. It includes: 1. The concentrations of stock standard solutions and working standard solutions of paracetamol and salicylamide that were prepared. 2. Regression analyses that were performed to determine the relationships between concentration and absorbance of the working standard solutions. 3. Calculations that were carried out to determine the concentrations of paracetamol and salicylamide in an unknown sample based on its measured absorbance values. 4. The determined concentrations of paracetamol and salicylamide in the unknown sample were 11.19 ppm

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    © All Rights Reserved
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    41 views16 pages

    Kelompok Kfa

    Uploaded by

    Maulidya Silviana
    This document contains the results of an analytical chemistry practicum group measuring the concentrations of paracetamol and salicylamide in samples. It includes: 1. The concentrations of stock standard solutions and working standard solutions of paracetamol and salicylamide that were prepared. 2. Regression analyses that were performed to determine the relationships between concentration and absorbance of the working standard solutions. 3. Calculations that were carried out to determine the concentrations of paracetamol and salicylamide in an unknown sample based on its measured absorbance values. 4. The determined concentrations of paracetamol and salicylamide in the unknown sample were 11.19 ppm

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    of 16

    PRAKTIKUM KIMIA

    FARMASI ANALISIS
    KELOMPOK 4
    AMALIA INDAH RIZKY 201910410311042
    MOH. ALWAN FALUTHI KELIANDAN 201910410311043
    FITRI ARDININGSY ANTIKA 201910410311044
    FIDHDHAH FAKHIRAH RAHMAN 201910410311045
    NUR IFTA MUFIDAH 201910410311046
    SYAILI RAHMA 201910410311047
    HUSNA RUSDIANA 201910410311050
    ALFIKA THISSWANDA 201910410311051
    TRI LUTFIANA MARETHA 201910410311102
    ZADA FARAH SALSABILA 201910410311103
    MUHAMMAD DONNY CAHYA 201910410311206
    KHARISMA PUTRI ENDI 201910410311207
    MEIRIZQA PUTRI AULIA AZIZA 201910410311258
    ELZA NUR RAHMAH SALZABILLAH 201910410311259
    Konsentrasi
    -Larutan Baku Induk I Paracetamol
    Konsentrasi = PPM = mg/L
    = 99,1 mg/100 ml
    = 99,1 mg/0,1 L
    = 991 ppm

    -Larutan Baku Induk II Paracetamol (menggunakan rumus pengenceran)


    V1 . N1 = V2 . N2
    1,0 ml . 991 ppm = 25,0 ml . N2
    N2 = 39,64 ppm

    -Konsentrasi Larutan Baku Kerja 1-5 Paracetamol

    Baku Kerja 1
    V1 . N1 = V2 . N2
    1,0 ml . 39,64 ppm = 10,0 ml . N2
    N2 = 3,964 ppm  
    Baku Kerja 2
    V1 . N1 = V2 . N2
    2,0 ml . 39,64 ppm = 10,0 ml . N2
    N2 = 7,928 ppm

    Baku Kerja 3
    V1 . N1 = V2 . N2
    3,0 ml . 39,64 ppm = 10,0 ml . N2
    N2 = 11,892 ppm
     
    Baku Kerja 4
    V1 . N1 = V2 . N2
    4,0 ml . 39,64 ppm = 10,0 ml . N2
    N2 = 15,856 ppm
     
    Baku Kerja 5
    V1 . N1 = V2 . N2
    5,0 ml . 39,64 ppm = 10,0 ml . N2
    N2 = 19,82 ppm
    2. Konsentrasi
    -Larutan Baku Induk 1 Salisilamid (dik. volume larutan baku induk 1 adalah 100,0 ml)
    konsentrasi : ppm = mg/L
    100,4 mg/100 ml
    100,4 mg/0,1 L
    1004 ppm

    -Larutan Baku Induk 2 Salisilamid (menggunakan rumus pengenceran)


      V1 . N 1 = V2 . N2
    1,0 ml . 1004 ppm = 25,0 ml . N2
    1004 = 25,0 . N2
    N2 = 40,16 ppm

    -Konsentrasi Larutan Baku Kerja 1-5

    Baku Kerja 1
    V 1 . N1 = V2 . N2
    1,0 ml . 40,16 ppm = 10,0 ml . N2
    40,16 = 10 . N2
    N2 = 4,016 ppm
    Baku Kerja 2
    V 1 . N 1 = V 2 . N2
    2,0 ml . 40,16 ppm = 10,0 ml . N2
    N2 = 8,032 ppm
     
    Baku Kerja 3
    V 1 . N 1 = V 2 . N2
    3,0 ml . 40,16 ppm = 10,0 ml . N2
    N2 = 12,048 ppm
     
    Baku Kerja 4
    V 1 . N 1 = V 2 . N2
    4,0 ml . 40,16 ppm = 10,0 ml . N2
    N2 = 16,064 ppm
     
    Baku Kerja 5
    V 1 . N 1 = V 2 . N2
    5,0 ml . 40,16 ppm = 10,0 ml . N2
    N2 = 20,08 ppm
    3. Regresi Baku Kerja

     λParacetamol

    Baku kerja 1 3,964 0,389


    a : 0,0178
    Baku kerja 2 7,928 0,795
    b : 0,09767
    Baku kerja 3 11,892 1,165
    r : 0,9964
    Baku kerja 4 15,856 1,651
    Baku kerja 5 19,82 1,897

    a : 0,0178
    b : 0,09767
    r : 0,9964
     λSalisilamid
    Baku kerja 1 4,016 0,066
    Baku kerja 2 8,032 0,134
    Baku kerja 3 12,048 0,243
    Baku kerja 4 16,064 0,287
    Baku kerja 5 20,08 0,353

    a : -1,5 x 10-3
    b : 0,0181
    r : 0,9915
     λPerpotongan (Paracetamol)

    Baku kerja 1 3,964 0,071


    Baku kerja 2 7,928 0,142
    Baku kerja 3 11,892 0,187
    Baku kerja 4 15,856 0,275
    Baku kerja 5 19,82 0,335

    a : 0,0037 (3,7 x 10-3)


    b : 0,0167
    r : 0,9964
     λPerpotongan (Salisilamid)
    Baku kerja 1 4,016 0,038
    Baku kerja 2 8,032 0,087
    Baku kerja 3 12,048 0,139
    Baku kerja 4 16,064 0,178
    Baku kerja 5 20,08 0,240

    a : -0,0121
    b : 0,0123
    r : 0,9982
    4. Konsentrasi Sampel yang Terukur (Paracetamol dan Salisilamid)

    λ Paracetamol
    y = bxpct + a1 + bxs + a1
    1,264 = 0,0977 xp + 0,0178 + 0,0181 xs + (-0,0015)
    1,264 - 0,0178 + 0,0015 = 0,0977 xp + 0,0181 xs
    1,2477 = 0,0977 xp + 0,0181 xs

    λ Perpotongan
    y = bxpct + a1 + bxs + a1
    0,283 = 0,0167 xp + 0,0037 + 0,0123 xs + (-0,0121)
    0,283 – 0,0037 + 0,0121 = 0,0167 xp + 0,0123 xs
    0,2914 = 0,0167 xp + 0,0123 x­s

     1,2477 = 0,0977 xp + 0,0181 xs (x 0,0167)


    0,2914 = 0,0167 xp + 0,0123 xs (x 0,0977)

    0,0208 = 0,0016 xp + 0,0003 xs


    0,0285 = 0,0016 xp + 0,0012 xs
    -0,0077=. -0,0009 xs
    xs. = -0,0077/-0,0009
    xs = 8,56 ppm
    1,2477 = 0,0977 xp + 0,0181 xs
    1,2477 = 0,0977 xp + (0,0181 . 8,56)
    1,2477 = 0,0977 xp + 0,1549
    1,2477 – 0,1549 = 0,0977 xp
    1,0928 = 0,0977 xp
    xp = 11,19 ppm
    5. Kadar Sampel (Paracetamol dan Salisilamid)

    Kadar Paracetamol
    Xp = 11,19 ppm = 11,19mg / 1000ml
    = 0,0112 gram / 1000ml
    = 0,0011 gram / 100ml
    = 0,0011 gram% b/v

    Kadar Salisilamid
    Xs = 8,56 ppm = 8,56 mg / 1000ml
    = 0,0086 gram / 1000ml
    = 0,0009 gram / 100 ml
    = 0,0009 gram% b/v
    Terima kasih

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