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    Liver Anatomy & Functions

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    Sheikh Sharfuddin Rajeev
    The liver is the largest gland in the body, located in the upper right quadrant of the abdomen under the diaphragm. It has four lobes and contains hepatocytes that produce bile which flows through bile canaliculi and ducts. The gallbladder stores and concentrates bile produced by the liver. The liver performs many vital metabolic functions including synthesizing proteins and carbohydrates, breaking down toxins and red blood cells, and producing coagulation factors and albumin.

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    Liver Anatomy & Functions

    Uploaded by

    Sheikh Sharfuddin Rajeev
    54 views14 pages
    The liver is the largest gland in the body, located in the upper right quadrant of the abdomen under the diaphragm. It has four lobes and contains hepatocytes that produce bile which flows through bile canaliculi and ducts. The gallbladder stores and concentrates bile produced by the liver. The liver performs many vital metabolic functions including synthesizing proteins and carbohydrates, breaking down toxins and red blood cells, and producing coagulation factors and albumin.

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    The liver is the largest gland in the body, located in the upper right quadrant of the abdomen under the diaphragm. It has four lobes and contains hepatocytes that produce bile which flows through bile canaliculi and ducts. The gallbladder stores and concentrates bile produced by the liver. The liver performs many vital metabolic functions including synthesizing proteins and carbohydrates, breaking down toxins and red blood cells, and producing coagulation factors and albumin.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPT, PDF, TXT or read online from Scribd
    Download as ppt, pdf, or txt
    54 views14 pages

    Liver Anatomy & Functions

    Uploaded by

    Sheikh Sharfuddin Rajeev
    The liver is the largest gland in the body, located in the upper right quadrant of the abdomen under the diaphragm. It has four lobes and contains hepatocytes that produce bile which flows through bile canaliculi and ducts. The gallbladder stores and concentrates bile produced by the liver. The liver performs many vital metabolic functions including synthesizing proteins and carbohydrates, breaking down toxins and red blood cells, and producing coagulation factors and albumin.

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    Liver: anatomy & functions

    Pavle Pei Tukuljac


    Mentor: A. mega Horvat

    Anatomy
    Largest gland in the body (1.5 Kg) Under the diaphragm, within the rib cage in the upper right quadrant of the abdomen

    Anatomy
    4 Lobes Major: left and right Minor: caudate and quadrate Ducts Common hepatic Cystic Common bile Choledochus
    From gallbladder

    Joins pancreatic duct at hepatopancreatic ampulla

    GALLBLADDER ANATOMY

    GALLBLADDER ANATOMY
    Thin-walled green muscular sac On the inferior surface of the liver Stores bile that is not immediately needed for digestion When the muscular wall of the gallbladder contracts bile is expelled into the bile duct

    LIVER

    GALL BLADDER

    BILE
    BILE bile salts, bile pigments, cholesterol, neutral fats, phospholipids and electrolytes

    Liver produces 0.5-1 l of bile daily


    Bile salts emulsify fats
    LIVER

    GALL BLADDER

    LIVER ANATOMY
    Liver lobules hexagonal structures consisting of hepatocytes Hepatocytes radiate outward from a central vein At each of the six corners of a lobule is a portal triad Liver sinusoids

    LIVER ANATOMY
    Hepatocytes produce bile

    Bile flows through canals called bile canaliculi to a bile duct

    Bile ducts leave the liver via the common hepatic duct

    LIVER ANATOMY

    20 %

    80 %

    Functions
    Metabolic Synthesis Breakdown Other functions storage of vitamin A,D,B12,F Excretion of waste products from bloodstream into bile Vascular storage of blood

    Synthesis
    Protein metabolism Synthesis of amino acids Carbohydrate metabolism Gluconeogenesis Glycogenolysis Glycogenesis Lipid metabolism Cholesterol synthesis Lipogenesis Production of coagulation factors I, II, V, VII, IX, X and XI, and protein C, protein S and antithrombin Main site of red blood cell production Produces insulin-like growth factor 1 (IGF-1), a polypeptide protein anabolic effects Production of trombopoetin

    Breakdown
    Breaks down insulin and other hormones Breaks down hemoglobin Breaks down or modifies toxic substances (methylation) sometimes results in toxication Converts ammonia to urea

    Other functions
    Produces albumin, the major osmolar component of blood serum Synthesizes angiotensinogen, the hormone responsible for raising blood pressure when activated by renin (enzyme released when the kidney senses low blood pressure)

    References
    http://en.wikipedia.org/wiki/Liver http://www.youtube.com/watch?v=J0AjkKRxb WM&feature=related http://www.mamashealth.com/organs/liver.as p www.medterms.com http://www.youtube.com/watch?v=bx6kj6xLC Zw

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