AP Prelim
AP Prelim
AP Prelim
(Cardiac Physiology)
C. SYSTEMIC PHYSIOLOGY
• ANA- Apart
- All aspects of the functions of specific
• TOMY- To cut
organs.
Physiology- Normal Function - They are interconnected to another
system.
D. PATHOLOGIC PHYSIOLOGY
TYPES OF ANATOMY - Effects of disease on organ system
function.
A. GROSS/MACROSCOPIC ANATOMY
- Big enough to be studied. Level of structure organization of the body
- Can be studied with an unaided eye.
1. CHEMICAL LEVEL
• SYSTEMIC ANATOMY
- Smallest unit of matter
- Deals with different systems of our
- Ex. (Atom, Molecule)
body.
2. CELLULAR LEVEL
- Ex. (Nervous System, Circulatory)
- Studies body cell
• REGIONAL ANATOMY
- Cell + Cell = Tissue
- Study of structure by body region.
3. TISSUE LEVEL
- Ex. (Head Region)
- Group of cells with similar structure
• SURFACE ANATOMY
and function together.
- Study of the body landmark on the
4. ORGAN LEVEL
body surface of different Visceral
- Different types of tissue joined
Organ (covering or protective layer
of organs) together with the same function.
D. NEURO ANATOMY
• CAVITY- Hole or Space
- Gross features and development of
• PELVIC CAVITY OF FEMALE
the nervous system.
- round shape
- Conduction of the electricity in the
- Gynae
brain
- Reproductive system
TYPES OF PHYSIOLOGY • PELVIC CAVITY OF MALE
A. CELL PHYSIOLOGY - Heart shape
- Function of a living cell • PERENNIAL AREA
B. SPECIAL PHYSIOLOGY -
- Studies of specific organ
PERINEUM - Ex. (Mast + Ectomy = Mastectomy)
- External Genitalia • + Otomy – to cut or to open surgically
- Ex. (Crani + otomy = Craniotomy)
▪ UPPER EXTREMITIES- Upper Limb
• + Ostomy – Creates an opening
(shoulder, arm, elbow, forearm and hand)
- Ex. (Colon + Ostomy = Colostomy)
▪ LOWER EXTREMITIES- Lower Limb
(Hip; Thigh; Knee; Leg; Ankle; Foot)
VENTRAL/ANTERIOR – Front
▪ ANATOMICAL POSITION DORSAL/POSTERIOR - back
LATERAL- Side
INTERMEDIATE- Between a more medial
PROXIMAL- Closer to the origin
DISTAL- Far from the origin
SUPERFICIAL- External, surface
DEEP- Internal, away from body surface
1. FLEXION
- Bending
- Decreasing the angle
2. EXTENSION 14. OPPOSITION
- Straightening - All fingers touching
- Decreasing the angle the thumb
3. HYPEREXTENSION
- Can go beyond a 90-degree angle
4. ABDUCTION LIFE PROCESSES
- Moving away from the median 1. MOVEMENT
5. ADDUCTION - It helps the function of our other
- Movement toward the median systems
6. ROTATION 2. RESPONSIVENESS
- Long axis bone (ball&socket) - Ability to sense stimuli
- - Reaction to a certain stimulus
7. CIRCUMDUCTION
- Either the combination of the four *Stimulus happens within internal and
(Flexion, Extension, Abduction, external environment
Adduction) 3. DIGESTION
8. EVERSION - Breaking down food into smaller
- For the sole of our foot particles
- Lateral movement (palabas) • MECHANICAL DIGESTION
9. INVERSION - happens in your mouth (teeth,
- For the sole of our foot tongue, saliva, and mandible)
- Movement towards medial (papasok) - Bolus – food mixed with saliva
10. SUPINATION - Chyme – Digestive enzymes
• CHEMICAL DIGESTION
- Happens in the stomach
- stomach produces chemical COMPONENTS OF EXTRINSIC
substances such as gastric juice 1. RECEPTOR
- food stays in the stomach for 2-4 - Response to the stimuli
hours 2. CONTROL CENTER
4. METABOLISM - Determines appropriate response
- Different chemical substances 3. EFFECTOR
happen in our body - Provides all the means for the
- Respiration response to the stimulus
- Bone metabolizes calcium
1. ORGANELLES
❖ PASSIVE TRANSPORT
- The little organs of our cells
A. DIFFUSION
- Specialized cellular compartments
- Molecules to scatter themselves
each performing its own job to
throughout the available space
maintain the life of the cell.
D. GOLGI APPARATUS OR GOLGI BODY
A. MITOCHONDRIA (DICTYOSOMES)
- Are usually depicted as tiny threadlike - Appears as a stock of flattened
(mitos = thread) or sausage-shaped membranous sacs
organelles - Connected to RER
- Consists of double membrane, the - Gather excreta of our cell
outer membrane is smooth and - The cell membrane will open to
featureless but the inner membrane dispose of waste that eventually
has shelflike protrusions called becomes our excreta
cristae - Functions to accumulate and
- Powerhouse of the cell concentrate the secretory products
B. RIBOSOMES E. LYSOSOMES
- Are tiny, dark bodies made of CHON - Contains powerful digestive enzymes
and a variety of RNA called ribosomal - Defends the cell against foreign
RNA substances
- Actual site of CHON synthesis - Abundant in white blood cells (WBS)
- Can be found in Cytoplasm and RER
- Synthesizes or simplified our protein I. PRIMARY LYSOSOMES
o These are not yet engaged in
to convert to amino acid
digestive activity
II. SECONDARY LYSOSOMES
C. ENDOPLASMIC RETICULUM o Site of current previous digestive
- The passageway activity
- Canal, tube o Has the ability to fight certain
- is a system of fluid filled cisterns organism
(tubules or canals) that coil and twist o “pro player”
through the cytoplasm III. RESIDUAL
- “Network within the cytoplasm” o Terminal phases of lysosomal
function
• ROUGH ENDOPLASMIC RETICULUM OR o Contains undigestible materials
GRANULAR ENDOPLASMIC RETICULUM
✓ Contains bound ribosomes hence F. PEROXISOMES
connected with CHON synthesis - Membranous sacs containing
✓ Connected to our ribosome powerful oxidase enzymes
✓ Only the protein will pass through - Detoxifies harmful and poisonous
substances such as alcohol and
RER throughout other part of the cell formaldehyde
• SMOOTH ENDOPLASMIC RETICULUM OR - Breaks down free-radicals
GRANULAR ENDOPLASMIC RETICULUM - Most important function is to disarm
✓ Does not contain ribosomes dangerous free-radicals
✓ Function in lipid metabolism and
detoxification ➢ VACUOLES – collected crystalline wastes
product of our cell which is the salt
(reason kung bakit may bato sa katawan
ang tao, dahil naipon sa cell)
2. INCLUSIONS TYPES OF INTRACELLULAR DIGESTION
- Are not functioning units but 1) AUTOPHAGY
chemicals substances that may not - Controlled degradation of organelles
be present in our cell. in a healthy cell
e.g Glycogen, Lipid, Pigments - When the cell is about to die, it’s either
becomes excreta or is eaten by
• GLYCOGEN
another cell
- Head glucose, sugar, carbohydrates
• LIPID
2) HETEROPHAGY
- Fats
- Degradation of exogenous material
• PIGMENTS
taken into the cell.
- Color
- “microorganism” huhulihin, kakainin,
itatapon.
3. CYTOSKELETON
- Framework of the cell CELL GROWTH AND REPRODUCTION
- Skeletal system of the cell A. CELL CYCLE
- Series of changes; from formation to
❖ MICROFILAMENTS division
- Thinnest cytoskeleton ➢ INTERPHASE (18-24 hrs)
❖ INTERMEDIATE FILAMENT - Inactive
- Help from desmosomes - Resting phase
❖ MICROTUBULES
- Determined the overall shape of the 4 PHASES
cell and distribution of organelles • G1 PHASE
- No DNA but RNA and CHON synthesis
➢ CENTRIOLES - Follows telophase of mitosis
- Rod-shaped bodies that lie at the right • S SYNTHESIS PHASE
angle to each other - DNA synthesis and replication
➢ BASAL BODIES
• G2 PHASE
- Anchoring points for cilia and flagella
- Final preparation for cell division
(sperm)
➢ CILIA
- Whip-like cellular extensions that B. CELL DIVISION
move substances along the cell - Shortest period of cell cycle
surface - Division of nucleus
➢ FLAGELLA
- Long centrioles TYPES OF NUCLEAR DIVISION
- Propel the cell ➢ MITOSIS – nuclear division of vegetative or
➢ MICROVILLI somatic cells (46 chromosomes)
- Finger-like extensions of the plasma ➢ MEIOSIS – formation of reproductive
membrane cells/gametes (23 chromosomes)
- Increase the area for absorption
4 PHASES OF MITOSIS (P.M.A.T)
1. PROPHASE
- Chromosomes progressively shorten
and thicken to form double structures
- Nucleolus gradually disappears - Avascular
2. METAPHASE • FUNCTIONS:
- Double chromosomes occupy the - Protection
plane of the plane of the equator of - Absorption
the centromere - Filtration
3. ANAPHASE - Secretion
- Separation of the sister chromatids
and passage as daughter
chromosomes to the opposite poles
4. TELOPHASE
- New nuclear membrane
- Nucleoli are reformed
• CLASSIFICATIONS
1. SIMPLE EPITHELIUM
- One layer of CELLS
2. STRATIFIED EPITHELIUM
- Two or more layers of cells
SIMPLE EPITHELIUM
- Concerned with absorption, secretion,
and filtration
CYTOKINESIS – Division of the cytoplasm
1. SIMPLE SQUAMOUS EPITHELIUM
TISSUES - Single thin layer of squamous cells
- Group of cells with similar structure - Flattened cells
and function - Like fish scales
• FOUR PRIMARY TYPES - Usually forms membranes where
1. Epithelial tissue (Epithelium) - covering filtration or exchange of substances by
2. Connective Tissue - support rapid diffusion occur.
3. Muscle Tissue - control
4. Nervous Tissue – movement
• EPITHELIAL TISSUE
- Epithe – laid on
- Covering
• Characteristics:
- Epithelial cells fit closely together to
form continuous sheets
- Has one free surface or edge. Apical
surface is exposed to the body to the
body’s exterior or to the cavity of the
internal organ.
- Has a basement membrane
2. SIMPLE CUBOIDAL EPITHELIUM 4. PSEUDOSTRATIFIED EPITHELIUM
- Cells that are wider than they are tall - Cells are shorter than the others
- Cube-like cells with large spherical - The nuclei appear in different heights
central nuclei above the basement membrane
- Common in glands and their ducts - PSEUDO – false
(salivary glands and pancreas
• NON- CILIATED
- Lining of the ducts of male and
accessory male repro
• CILIATED
- Lining of the respiratory tract (LUNGS)
3. SIMPLE COLUMNAR EPITHELIUM
- Tall cells STRATIFIED EPITHELIA
- Common in the GIT (stomach to the - Primary function is PROTECTION
anus)
➢ GOBLET CELLS – produce a 1. STRATIFIED SQUAMOUS EPITHELIUM
lubricating mucus - Most common stratified squamous
epithelium
- Consist of several layers (free edge
squamous cells; basement membrane
cuboidal or columnar)
- Common sites are those which
receive friction (esophagus, mouth,
outer layer of skin)
2. TRANSITIONAL EPITHELIUM
- Highly modified, stratified squamous
epithelium
- Cells have the ability to slide past one
another and change their shaped
- Common at the ureter and urinary 3. MUCO-SEROUS GLAND – mixed
bladder secretion (sublingual gland)
4. CYTOGENIC GLANDS – Produce cells
(testis, ovaries)
CONNECTIVE TISSUE
- Connects body parts
- Functions: supporting and binding
together
• Characteristics:
- Well vascularized (except tendons and
ligaments…poor blood supply)
• EXOCRINE GLAND
- Number of cells
1. UNICELLULAR GLAND = goblet cells
2. MULTICELLULAR GLAND = all glands
except goblets
2. CARTILAGE
• NATURE O SECRETION
1. MUCOUS GLAND – secretes thick - Less hard and more flexible
product (goblet cells) TYPES OF CARTILAGE
2. SEROUS GLAND – secretes thin 1. HYALINE – has abundant collagen
watery product (parotid gland) fibers hidden by a rubbery matrix e.g
trachea
2. FIBROLAST – forms the cushion like 2. ADIPOSE TISSUE – fat
disk between the vertebrae of the
spinal column
3. ELASTIC – structure with elasticity
desired e.g external ear
MUSCLE TISSUE
- Are highly specialized to contract or
shorten to produce movement
JOINTS
- Arthroses
- Between 2 or more bone
• TYPES OF JOINTS (3)
• FIBROUS JOINTS
- Connective tissue holds bone together
- Immovable (synarthroses)
• CARTILAGENOUS JOINTS
- Cartilage holds the bone
- Slightly movable
• SYNOVIAL JOINTS
- A cavity fluid in bones (between)
- Freely movable (diarthrosis)
TYPES
• HINGE JOINT
- One direction
- Elbow and knee
• FIRST JOINT
- Rotation
- Atlantoaxial (c1 and c2)
• CONDYLOID
- 2 directions
- Wrist joint
• SADDLE JOINT
- Deeper articulate
• BALL AND SOCKET
- Allows in any movement
• GLIDING JOINT
- Plain joints
- Slides over one
- Commonly happen with Carpal and
tarsal