Organic Short Notes

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Ralfe

cukr iter Ratea Intva


kn. pour SN² *
AlVyldbn Hot6au's |() by
Comt. huh favpure) Teaction
is
(R-x)+
ENu)K2Lk-X]
SN2.
R-OH-Rso
Dmso T7ans Cis
R
by (sN')
SN2
CMS M3 Cz9su K
lhot Agf
ets H Trams nso C2
-Czhs CHy-4 SN Et
t
t SN DMSo HMe
koH Averson
co4Walde me H
shme
Me
SMe me
Dr Acetone
NaIy
SN' CKu b Acetoné
Aguous CHzcn-,Ph
Abridy neoputyl 3, R
X
2",benyytie cH3,-<u-cus,
1°4allylc -CH-cHy sheutdl
be R-x;R InN*SFor
and
2 1
R-o-pK) R-R') R-cEC-R R-C R-N) RsH) R-o-R [R-OH
NaN2
RCzcH NHj+
Na HCN+NeOk OH+Na
JR'SH
NaD4 ho4GR\R'^gx
pho CaHso Of
R-XSN'oFSECONDKEXAMPLES
CMso REARRANGEMEN]
DMF/omso SN2 NO
THEN
SN A/8 THE
ME Csenes +Mior120’Masor
(1 Ph-CH-ÇH-CHa-I
CooMr
+Minor2) 4N-cus-çH-cON
Majpr
X
s stable) (Mere
13 Ph-e-CHy-cHrcH3
Minor
(Diastereomers)
bheractir double stahle) less
H H
Ph-c-c-cH-
CM3
JRDS CH3
eIs/Tans Actone
CH-cH=CH-cH,-bCHI CM,-cM3Ph--cH- stable) (les
H CH-cH skagtJ,2CH3 C--c
RDs|CausoH stable) (Vore.
cH-I =C4 - Ch-eH (Majov
(Min) Prsds 4, s Mino
M30H’c--c-cto-c-oc
-3fat H3roe A-c-x
iastereotr
(dy)
stble) (More & stade) (less
C
shigt 1,24 c-c-cB
(nino) (Mino) (MagoDH,
diastereo Hf-¢-ch,-I H (3)
(ajl) wer
[B) c-c-t-c OH2
Ph
H
Me
AcctoneOc--BY
me (-c-c-c H20
Ag Me SN'c*Rx Exanghleso
korued þroduts
ar Me
mang How
sN by
majr prauct
Needé 3>2°>1° subst, +Strord
Base t
RerER
n3 Condtins, H-pwil be
whem Caser a
Maor pndut- CHy-eM-CMC*S
CHaH=cHCH,+Buten By Mno
Cks- cM;-CH3 CrM^o C2HsoH
2 CH3-C)-c- c-cM} NH2 CH CH=
B He)sf)
CIs/TRANSdus
CH3-CH,-cH= 7 bds
CIs)Trams with existing (majr)
o. Diastertoms ocH=n-H-cy
PhrcHM-h
ail give G. Diast. Ph-cH2-eH-Cy-cu
- boductf) PhcH-C4¢
Same (mino3

CHo CHacHeMacM
CHyon
(Ci) eN3 sMina)
-CH-cHNH

c2M5 I
AgoHtA
() CH-M N-CH
Ce Ce
Tians wil not DMeI
Heat? Aea02.R0s+o wll
Thojto’A..MC-Cu-cHcy Thozy cHacer
ALOHLS(SP. Magor) weh

Ph-NPh-nNGSNg
uO-N-geKs t
Me-Ocn=Å-CH= MAPD2-CH
CH,SROAD
Ph-c
RX

NaNM

R-cN R-eH-CHs

Pho

3 cooEt)Etee
H-o-f

CDCH3/
H-toet eH-cns
Pce/
Phc
<R-CnCM;
efoet
2NeBr R
etoH!
tNgt RcHN,C
3RCHNM DR-CENR-NO2 to)
B2)R-Nc
|RNHCW3
gide
9DIeAL-H
RCH=NOH oH R-c=0k R--X Akene
tiomdl

-&'RCHgOH sh|
RCHNH |RcHNH,(eAlcoho) Bytognation
RNHWydgenatRCH, OH+ROH KPAlcoha
1°Alchols
( R-CH-CH
RCH=o7RCH
ALD.
ReduLced
R-H HX
4-
1/2/3on} R
ARIKan

+H0
+R
1°Alce Alaha
Pot4O
7
-addition oß ORed 5)
-R'DiAL
cEN - H2
Reduteon(
Natc2M_0H|
Clemmensen' Ntro
Aeid
Ha+NyPqrd
Na
s NM, BH4uACH4
+s/Suindline P+NI Yeduces
Yeduces
NHa
GAL-H" CDi'so is Yeadts
dioy 2507 ANTI'(TFans-fradut
SHOH+RoH aAdiB0Re0RdCHu c. t eis
-Rroduat addi' strongest
N
Red.(Zn-Hg educes only all wih
gRCH=O butyl oH)
R-x,RCH=O,
esceft
all
RCHo+aluminium
NHR-=Rlindlars
3 R-CECR
RCEc, kn) ( reduengYecs ale oyseept
R-x,R-CH=O
(Roscnmunds Pha),Rhcl indlers + ALENE
ejoeekt
Cone
hydvide) aldeykosane
catayst ANenjAmy|
ESTER,AMIDE
agit,Rac=o4R-e-:
Hee)
Amide&ALVYMEE
+H2
Reduceserya. veduces
ie7srS
ds OMPVReduct.
CH)Ocg Pastial
ketone any k
Rm) ACIDs.
Rn.) /

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