o-Phenylene Diamine MATERIAL SAFETY DATA SHEET

CAS No 95-54-5 SDS/MSDS

SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1 Product identifiers
Product name : o-Phenylene Diamine
CAS-No. : 95-54-5
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Industrial & for professional use only.
1.3 Details of the supplier of the safety data sheet
Company : Central Drug House (P) Ltd
7/28 Vardaan House
New Delhi-10002
INDIA
Telephone : +91 11 49404040
Email : [email protected]

1.4 Emergency telephone number

Emergency Phone # : +91 11 49404040 (9:00am - 6:00 pm) [Office hours]

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture

Classification according to Regulation (EC) No 1272/2008
Acute toxicity, Oral (Category 3), H301
Acute toxicity, Inhalation (Category 4), H332
Acute toxicity, Dermal (Category 4), H312
Eye irritation (Category 2), H319
Skin sensitisation (Category 1), H317
Germ cell mutagenicity (Category 2), H341
Carcinogenicity (Category 2), H351
Acute aquatic toxicity (Category 1), H400
Chronic aquatic toxicity (Category 1), H410
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram

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 Signal word Danger
Hazard statement(s)
H301 Toxic if swallowed.
H312 + H332 Harmful in contact with skin or if inhaled
H317 May cause an allergic skin reaction.
H319 Causes serious eye irritation.
H341 Suspected of causing genetic defects.
H351 Suspected of causing cancer.
H410 Very toxic to aquatic life with long lasting effects.
Precautionary statement(s)
P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection.
P301 + P330 + P331 + P310 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Immediately
call a POISON CENTER or doctor/ physician.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
Supplemental Hazard none
Statements
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent, bioaccumulative and
toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

SECTION 3: Composition/information on ingredients

3.1 Substances
Synonyms : OPD
1,2-Diaminobenzene
1,2-Phenylenediamine

Formula : C6H8N2
Molecular weight : 108,14 g/mol
CAS-No. : 95-54-5
EC-No. : 202-430-6
Index-No. : 612-145-00-2

Hazardous ingredients according to Regulation (EC) No 1272/2008

Component Classification Concentration
o-Phenylenediamine
CAS-No. 95-54-5 Acute Tox. 3; Acute Tox. 4; <= 100 %
EC-No. 202-430-6 Eye Irrit. 2; Skin Sens. 1;
Index-No. 612-145-00-2 Muta. 2; Carc. 2; Aquatic
Acute 1; Aquatic Chronic 1;
H301, H332, H312, H319,
H317, H341, H351, H400,
H410
M-Factor - Aquatic Acute: 1 -
Aquatic Chronic: 1
For the full text of the H-Statements mentioned in this Section, see Section 16.

SECTION 4: First aid measures

4.1 Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
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 If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available

SECTION 5: Firefighting measures

5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx)
5.3 Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information
No data available

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures
Wear respiratory protection. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure
adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
For personal protection see section 8.
6.2 Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the
environment must be avoided.
6.3 Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed
containers for disposal.
6.4 Reference to other sections
For disposal see section 13.

SECTION 7: Handling and storage

7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed.
For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Recommended storage temperature 2 - 8 °C

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 Moisture sensitive. Store under nitrogen. May darken on storage
Storage class (TRGS 510): Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous
materials causing chronic effects
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

8.1 Control parameters
Components with workplace control parameters
8.2 Exposure controls
Appropriate engineering controls
Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling
the product.
Personal protective equipment
Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and approved under
appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
Body Protection
Complete suit protecting against chemicals, The type of protective equipment must be selected
according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face particle
respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering
controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use
respirators and components tested and approved under appropriate government standards such
as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so. Do not let product enter drains . Discharge into the
environment must be avoided.

SECTION 9: Physical and chemical properties

9.1 Information on basic physical and chemical properties
a) Appearance Form: solid
Colour: white, tan
b) Odour No data available
c) Odour Threshold No data available
d) pH 8,7
e) Melting point/freezing Melting point/range: 98 - 102 °C
point
f) Initial boiling point and 256 - 258 °C
boiling range
g) Flash point 136 °C - closed cup
h) Evaporation rate No data available
i) Flammability (solid, gas) No data available
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 j) Upper/lower Lower explosion limit: 1,5 %(V)
flammability or
explosive limits
k) Vapour pressure 3,27 hPa at 100 °C
0,01 hPa at 25 °C
0,001 hPa at 20 °C - OECD Test Guideline 104
l) Vapour density No data available
m) Relative density 1,030 g/cm3 -
n) Water solubility 39,3 g/l at 20 °C - OECD Test Guideline 105
o) Partition coefficient: n- log Pow: 0,12 at 25 °C - OECD Test Guideline 107
octanol/water
p) Auto-ignition No data available
temperature
q) Decomposition No data available
temperature
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
Bulk density 0,74 g/cm3 at 24 °C

SECTION 10: Stability and reactivity

10.1 Reactivity
No data available
10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
No data available
10.4 Conditions to avoid
No data available
10.5 Incompatible materials
Strong oxidizing agents
10.6 Hazardous decomposition products
Other decomposition products - No data available
In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects
Acute toxicity
No data available
LC50 Inhalation - Rat - male - 4 h - 3,6 mg/l
Skin corrosion/irritation
Skin - Rabbit
Result: No skin irritation - 4 h
(OECD Test Guideline 404)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Irritating to eyes.
(OECD Test Guideline 405)
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 Respiratory or skin sensitisation
Maximisation Test (GPMT) - Guinea pig
Result: May cause sensitisation by skin contact.
Germ cell mutagenicity
In vitro tests showed mutagenic effects
Ames test
S. typhimurium
Result: negative

Mouse
Result: negative
Carcinogenicity
Limited evidence of carcinogenicity in animal studies
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
Additional Information
Repeated dose Rat - male - Oral - NOAEL : 400 mg/kg - OECD Test Guideline 407
toxicity
RTECS: Not available
Exposure can cause numbness, tingling, and weakness in extremities., Nausea, Dizziness, Headache,
Central nervous system depression, To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.

SECTION 12: Ecological information

12.1 Toxicity
Toxicity to fish static test LC50 - Pimephales promelas (fathead minnow) - 44 mg/l - 96 h
(OECD Test Guideline 203)
Toxicity to daphnia and semi-static test EC50 - Daphnia magna (Water flea) - 1,4 mg/l - 48 h
other aquatic
invertebrates
Toxicity to algae static test EC50 - Pseudokirchneriella subcapitata - 0,16 mg/l - 96 h
12.2 Persistence and degradability
Biodegradability aerobic - Exposure time 28 d
Result: 0 % - Not biodegradable
(OECD Test Guideline 301C)
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available

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12.5 Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and
toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
12.6 Other adverse effects
Very toxic to aquatic life with long lasting effects.

SECTION 13: Disposal considerations

13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
Contaminated packaging
Dispose of as unused product.

SECTION 14: Transport information

14.1 UN number
ADR/RID: 1673 IMDG: 1673 IATA: 1673
14.2 UN proper shipping name
ADR/RID: PHENYLENEDIAMINES
IMDG: PHENYLENEDIAMINES
IATA: Phenylenediamines
14.3 Transport hazard class(es)
ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1
14.4 Packaging group
ADR/RID: III IMDG: III IATA: III
14.5 Environmental hazards
ADR/RID: yes IMDG Marine pollutant: yes IATA: no

14.6 Special precautions for user

No data available

SECTION 15: Regulatory information

This safety datasheet complies with the requirements of Regulation (EC) No. 453/2010.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture

15.2 Chemical Safety Assessment

For this product a chemical safety assessment was not carried out

SECTION 16: Other information

Full text of H-Statements referred to under sections 2 and 3.
H301 Toxic if swallowed.
H312 Harmful in contact with skin.
H312 + H332 Harmful in contact with skin or if inhaled
H317 May cause an allergic skin reaction.
H319 Causes serious eye irritation.
H332 Harmful if inhaled.
H341 Suspected of causing genetic defects.
H351 Suspected of causing cancer.
H400 Very toxic to aquatic life.
H410 Very toxic to aquatic life with long lasting effects.

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Further information
The above information is believed to be correct but does not purport to be all inclusive and shall be
used only as a guide. The information in this document is based on the present state of our
knowledge and is applicable to the product with regard to appropriate safety precautions. It does not
represent any guarantee of the properties of the product. Central Drug House (P) Ltd and its Affiliates
shall not be held liable for any damage resulting from handling or from contact with the above
product. See www.cdhfinechemical.com for additional terms and conditions of sale.

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