SAFETY DATA SHEET Version 6.

4
Revision Date 07/17/2020
Print Date 11/20/2020

SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1 Product identifiers
Product name : Ammonium hydroxide solution
Product Number : 318612
Brand : Fluka
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Synthesis of substances

1.3 Details of the supplier of the safety data sheet

Company : Sigma-Aldrich Inc.
3050 Spruce Street
ST. LOUIS MO 63103
UNITED STATES
Telephone : +1 314 771-5765
Fax : +1 800 325-5052
1.4 Emergency telephone
Emergency Phone # : 800-424-9300 CHEMTREC (USA) +1-703-
527-3887 CHEMTREC (International) 24
Hours/day; 7 Days/week

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
Acute toxicity, Oral (Category 4), H302
Skin corrosion (Category 1B), H314
Serious eye damage (Category 1), H318
Short-term (acute) aquatic hazard (Category 2), H401
Long-term (chronic) aquatic hazard (Category 3), H412
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 GHS Label elements, including precautionary statements
Pictogram

Signal word Danger

Hazard statement(s)
H302 Harmful if swallowed.

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 H314 Causes severe skin burns and eye damage.
H401 Toxic to aquatic life.
H412 Harmful to aquatic life with long lasting effects.
Precautionary statement(s)
P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection.
P301 + P312 + P330 IF SWALLOWED: Call a POISON CENTER/ doctor if you feel
unwell. Rinse mouth.
P301 + P330 + P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated
clothing. Rinse skin with water/ shower.
P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable
for breathing. Immediately call a POISON CENTER/ doctor.
P305 + P351 + P338 + IF IN EYES: Rinse cautiously with water for several minutes.
P310 Remove contact lenses, if present and easy to do. Continue
rinsing. Immediately call a POISON CENTER/ doctor.
P363 Wash contaminated clothing before reuse.
P405 Store locked up.
P501 Dispose of contents/ container to an approved waste disposal
plant.

2.3 Hazards not otherwise classified (HNOC) or not covered by GHS

Lachrymator.

SECTION 3: Composition/information on ingredients

3.2 Mixtures
Synonyms : Ammonia aqueous
Ammonia water

Formula : H5NO
Molecular weight : 35.05 g/mol
Component Classification Concentration
Ammonium hydroxide
CAS-No. 1336-21-6 Met. Corr. 1; Acute Tox. 4; >= 10 - < 20
EC-No. 215-647-6 Skin Corr. 1B; Eye Dam. %
Index-No. 007-001-01-2 1; Aquatic Acute 1;
Aquatic Chronic 2; H290,
H302, H314, H318, H400,
H411
Concentration limits:
>= 5 %: STOT SE 3,
H335;
M-Factor - Aquatic Acute:
1
For the full text of the H-Statements mentioned in this Section, see Section 16.

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SECTION 4: First aid measures
4.1 Description of first-aid measures
General advice
Consult a physician. Show this material safety data sheet to the doctor in attendance.Move
out of dangerous area.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact
Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of
water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a
physician.Continue rinsing eyes during transport to hospital.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse
mouth with water. Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section
2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available

SECTION 5: Firefighting measures

5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Nitrogen oxides (NOx)
5.3 Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information
No data available

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate
ventilation. Evacuate personnel to safe areas.
For personal protection see section 8.
6.2 Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
Discharge into the environment must be avoided.

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6.3 Methods and materials for containment and cleaning up
Soak up with inert absorbent material and dispose of as hazardous waste. Keep in
suitable, closed containers for disposal.
6.4 Reference to other sections
For disposal see section 13.

SECTION 7: Handling and storage

7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid inhalation of vapor or mist.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Keep container tightly closed in a dry and well-ventilated place. Containers which are
opened must be carefully resealed and kept upright to prevent leakage.
Recommended storage temperature 2 - 8 °C
May develop pressure. Refrigerate before opening. Handle and open container with care.
Storage class (TRGS 510): 8B: Non-combustible, corrosive hazardous materials
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

8.1 Control parameters
Ingredients with workplace control parameters
Component CAS-No. Value Control Basis
parameters
Ammonium 1336-21-6 TWA 25 ppm USA. ACGIH Threshold Limit
hydroxide Values (TLV)

Remarks Upper Respiratory Tract irritation

Eye damage
STEL 35 ppm USA. ACGIH Threshold Limit
Values (TLV)
Upper Respiratory Tract irritation
Eye damage
TWA 25 ppm USA. NIOSH Recommended
18 mg/m3 Exposure Limits
Often used in an aqueous solution.
ST 35 ppm USA. NIOSH Recommended
27 mg/m3 Exposure Limits
Often used in an aqueous solution.
8.2 Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands
before breaks and at the end of workday.

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 Personal protective equipment
Eye/face protection
Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye
protection tested and approved under appropriate government standards such as
NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact
with this product. Dispose of contaminated gloves after use in accordance with
applicable laws and good laboratory practices. Wash and dry hands.
Full contact
Material: butyl-rubber
Minimum layer thickness: 0.3 mm
Break through time: 480 min
Material tested:Butoject® (KCL 897 / Aldrich Z677647, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.2 mm
Break through time: 60 min
Material tested:Dermatril® P (KCL 743 / Aldrich Z677388, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail
[email protected], test method: EN374
If used in solution, or mixed with other substances, and under conditions which
differ from EN 374, contact the supplier of the EC approved gloves. This
recommendation is advisory only and must be evaluated by an industrial hygienist
and safety officer familiar with the specific situation of anticipated use by our
customers. It should not be construed as offering an approval for any specific use
scenario.
Body Protection
Complete suit protecting against chemicals, The type of protective equipment must
be selected according to the concentration and amount of the dangerous substance
at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-
face respirator with multi-purpose combination (US) or type ABEK (EN 14387)
respirator cartridges as a backup to engineering controls. If the respirator is the sole
means of protection, use a full-face supplied air respirator. Use respirators and
components tested and approved under appropriate government standards such as
NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
Discharge into the environment must be avoided.

SECTION 9: Physical and chemical properties

9.1 Information on basic physical and chemical properties
a) Appearance Form: clear, liquid
Color: colorless
b) Odor No data available

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 c) Odor Threshold No data available
d) pH No data available
e) Melting No data available
point/freezing point
f) Initial boiling point No data available
and boiling range
g) Flash point ()No data available
h) Evaporation rate No data available
i) Flammability (solid, No data available
gas)
j) Upper/lower No data available
flammability or
explosive limits
k) Vapor pressure No data available
l) Vapor density No data available
m) Relative density 0.9 g/mL at 25 °C (77 °F)0.965 g/mL at 25 °C (77 °F)
n) Water solubility No data available
o) Partition coefficient: No data available
n-octanol/water
p) Autoignition No data available
temperature
q) Decomposition No data available
temperature
r) Viscosity No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
No data available

SECTION 10: Stability and reactivity

10.1 Reactivity
No data available
10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
No data available
10.4 Conditions to avoid
No data available
10.5 Incompatible materials
Zinc, Iron, Copper

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10.6 Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Nitrogen oxides (NOx)
Other decomposition products - No data available
In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects
Acute toxicity
No data available
Inhalation: No data available
Dermal: No data available
No data available
Skin corrosion/irritation
No data available
Serious eye damage/eye irritation
No data available
Respiratory or skin sensitization
No data available
Germ cell mutagenicity
No data available
Carcinogenicity
IARC: No ingredient of this product present at levels greater than or equal to 0.1% is
identified as probable, possible or confirmed human carcinogen by IARC.
No ingredient of this product present at levels greater than or equal to 0.1% is
identified as probable, possible or confirmed human carcinogen by IARC.
NTP: No ingredient of this product present at levels greater than or equal to 0.1% is
identified as a known or anticipated carcinogen by NTP.
No ingredient of this product present at levels greater than or equal to 0.1% is
identified as a known or anticipated carcinogen by NTP.
OSHA: No component of this product present at levels greater than or equal to 0.1% is
on OSHA’s list of regulated carcinogens.
No component of this product present at levels greater than or equal to 0.1% is
on OSHA’s list of regulated carcinogens.
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available

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 Additional Information
RTECS: Not available

Material is extremely destructive to tissue of the mucous membranes and upper respiratory
tract, eyes, and skin., spasm, inflammation and edema of the larynx, spasm, inflammation
and edema of the bronchi, pneumonitis, pulmonary edema, burning sensation, Cough,
wheezing, laryngitis, Shortness of breath, Headache, Nausea

SECTION 12: Ecological information

12.1 Toxicity
No data available
12.2 Persistence and degradability
No data available
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not
conducted
12.6 Other adverse effects
An environmental hazard cannot be excluded in the event of unprofessional handling or
disposal.
Toxic to aquatic life.

SECTION 13: Disposal considerations

13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a
licensed professional waste disposal service to dispose of this material. Dissolve or mix
the material with a combustible solvent and burn in a chemical incinerator equipped with
an afterburner and scrubber.
Contaminated packaging
Dispose of as unused product.

SECTION 14: Transport information

DOT (US)
UN number: 2672 Class: 8 Packing group: III
Proper shipping name: Ammonia solution
Reportable Quantity (RQ):
 Marine pollutant: yesPoison Inhalation Hazard: No

IMDG
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 UN number: 2672 Class: 8 Packing group: III EMS-No: F-A, S-B
Proper shipping name: AMMONIA SOLUTION
Marine pollutant : yes
Marine pollutant : yes

IATA
UN number: 2672 Class: 8 Packing group: III
Proper shipping name: Ammonia solution

SECTION 15: Regulatory information

SARA 302 Components

No chemicals in this material are subject to the reporting requirements of SARA Title III,
Section 302.
SARA 313 Components
The following components are subject to reporting levels established by SARA Title III,
Section 313:
CAS-No. Revision Date
Ammonium hydroxide 1336-21-6 2007-03-01

SARA 311/312 Hazards

Acute Health Hazard
Massachusetts Right To Know Components
No components are subject to the Massachusetts Right to Know Act.
Pennsylvania Right To Know Components
water CAS-No. Revision Date
7732-18-5

Ammonium hydroxide 1336-21-6 2007-03-01

California Prop. 65 Components

This product does not contain any chemicals known to the State of California to cause
cancer, birth, or any other reproductive defects.

SECTION 16: Other information

Further information
Copyright 2020 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies
for internal use only.
The above information is believed to be correct but does not purport to be all inclusive
and shall be used only as a guide. The information in this document is based on the
present state of our knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any guarantee of the properties of
the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any
damage resulting from handling or from contact with the above product. See
www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional
terms and conditions of sale.

The branding on the header and/or footer of this document may temporarily not visually
match the product purchased as we transition our branding. However, all of the

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 information in the document regarding the product remains unchanged and matches the
product ordered. For further information please contact [email protected].
Version: 6.4 Revision Date: 07/17/2020 Print Date: 11/20/2020

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