PEX-09-02 Zahra

Name: zahra aulia
Exercise 9: Renal System Physiology: Activity 2: The Effect of Pressure on Glomerular Filtration Lab Report
Pre-lab Quiz Results

You scored 100% by answering 4 out of 4 questions correctly.
1. Which of the following forces promotes filtration?

You correctly answered: c. blood pressure in the glomerular capillaries
2. The glomerular filtration rate can be altered by

You correctly answered: b. changing the afferent arteriole resistance.
3. In 24 hours human glomerular capillaries can filter as much as __________ liters of filtrate.
You correctly answered: c. 180
4. Which of the following statements about the filtrate in the renal corpuscle is false?
You correctly answered: d. Normally, more than 40% of the blood that enters the glomerular capillaries becomes filtrate.
12/08/23 page 1
Experiment Results
Predict Question:
Predict Question 1: What will happen to the glomerular capillary pressure and filtration rate if you increase the blood
pressure in the left source beaker?
Your answer : a. Both pressure and filtration rate will increase.
Predict Question 2: What will happen to the filtrate pressure in Bowman's capsule (not directly measured in this experiment)
and filtration rate if you close the one-way valve between the collecting duct and the urinary bladder?
Your answer : d. Pressure will increase and filtration rate will decrease.
Stop & Think Questions:

What is the important relation that underlies the observed increase in glomerular filtration rate when the blood pressure is
increased?
You correctly answered: c. pressure and flow are directly proportional.
What medical condition is analogous to the closed valve?

You correctly answered: b. a tumor obstructing the renal tubule
Experiment Data:
Afferent Radius Efferent Radius Beaker Press. Glomerular Glom. Filt. Rate Urine Volume Valve Status
(mm) (mm) (mm Hg) Press. (mm Hg) (ml/min) (ml)
0.50 0.45 70 49.72 58.57 161.76 open
0.50 0.45 80 52.40 91.78 186.23 open
0.50 0.45 90 55.08 124.99 200.44 open
0.50 0.45 100 57.76 158.20 209.72 open
0.50 0.45 70 49.72 58.57 161.76 open
0.50 0.45 70 49.72 26.94 0.00 closed
0.50 0.45 100 57.76 118.60 0.00 closed
0.50 0.45 100 57.76 158.20 209.72 open
12/08/23 page 2
Post-lab Quiz Results
You scored 100% by answering 4 out of 4 questions correctly.
1. In humans, the glomerular filtration rate normally ranges from

You correctly answered: b. 80 to 140 ml/min.
2. Which of the following does not have a significant impact on the glomerular filtration rate?
You correctly answered: d. renal tubule length
3. In the absence of any regulatory mechanisms, what do you think would happen to the glomerular filtration rate of a
person who experiences an increase in blood pressure?
You correctly answered: a. The glomerular filtration rate could increase.
4. What would happen to the glomerular filtration rate of a person who experiences a large hemorrhage?
You correctly answered: b. The glomerular filtration rate would decrease.
12/08/23 page 3
Review Sheet Results
1. As blood pressure increased, what happened to the glomerular capillary pressure and the glomerular filtration rate? How
well did the results compare with your prediction?
Your answer:
Ketika tekanan darah meningkat, tekanan kapiler glomerulus dan laju filtrasi pada glomerulus akan meningkat.
Meningkatnya tekanan darah mengakibatkan lebih banyak darah yang masuk ke glomerulus sehingga tekanan kapiler
glomerulus dan laju filtrasi ikut meningkat.
2. Compare the urine volume in your baseline data with the urine volume as you increased the blood pressure. How did the
urine volume change?
Your answer:
Ketika tekanan darah meningkat, volume urin akan meningkat sebab adanya peningkatan pada laju filtrasi dan tekanan
kapiler glomerulus sehingga volume darah yang masuk bertambah dan limbah yang dihasilkan (dibuang) juga bertambah.
3. How could the change in urine volume with the increase in blood pressure be viewed as being beneficial to the body?
Your answer:
Peningkatan tekanan darah mengakibatkan peningkatan volume urin sehingga limbah atau sampah yang perlu
diekskresikan lebih banyak dan lebih cepat.
4. When the one-way valve between the collecting duct and the urinary bladder was closed, what happened to the filtrate
pressure in Bowman's capsule (this is not directly measured in this experiment) and the glomerular filtration rate? How well
did the results compare with your prediction?
Your answer:
Ketika katup ditutup, tekanan glomerulus tetap sama namun laju filtrasi menurun. Hal ini menunjukkan bahwa dibuka atau
tidaknya katup, tekanan glomerulus akan tetap sama, tetapi laju filtrasi menurun sebab adanya filtrat di kandung kemih yang
tidak keluar dan glomerulus tidak dapat melakukan filtrasi sesering sebelumnya.
5. How did increasing the blood pressure alter the results when the valve was closed?
Your answer:
Tekanan darah yang meningkat pada katup tertutup, memengaruhi laju filtrasi glomerulus sebab urin atau filtrat yang
dihasilkan tidak dapat keluar.
12/08/23 page 4

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Name: zahra aulia

Pre-lab Quiz Results

1. Which of the following forces promotes filtration?

2. The glomerular filtration rate can be altered by

Stop & Think Questions:

What medical condition is analogous to the closed valve?

1. In humans, the glomerular filtration rate normally ranges from

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