Hasil Praktikum Urologi Activiti 2 Kel 2

Name: Kelompok 8
Exercise 9: Renal System Physiology: Activity 2: The Effect of Pressure on Glomerular Filtration Lab Report
Pre-lab Quiz Results

You scored 100% by answering 4 out of 4 questions correctly.
1. Which of the following forces promotes filtration?

You correctly answered: c. blood pressure in the glomerular capillaries
2. The glomerular filtration rate can be altered by

You correctly answered: b. changing the afferent arteriole resistance.
3. In 24 hours human glomerular capillaries can filter as much as __________ liters of filtrate.
You correctly answered: c. 180
4. Which of the following statements about the filtrate in the renal corpuscle is false?
You correctly answered: d. Normally, more than 40% of the blood that enters the glomerular capillaries becomes filtrate.
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Experiment Results
Predict Question:
Predict Question 1: What will happen to the glomerular capillary pressure and filtration rate if you increase the blood
pressure in the left source beaker?
Your answer : a. Both pressure and filtration rate will increase.
Predict Question 2: What will happen to the filtrate pressure in Bowman's capsule (not directly measured in this experiment)
and filtration rate if you close the one-way valve between the collecting duct and the urinary bladder?
Your answer : d. Pressure will increase and filtration rate will decrease.
Stop & Think Questions:

What is the important relation that underlies the observed increase in glomerular filtration rate when the blood pressure is
increased?
You correctly answered: c. pressure and flow are directly proportional.
What medical condition is analogous to the closed valve?

You correctly answered: b. a tumor obstructing the renal tubule
Experiment Data:
Afferent Radius Efferent Radius Beaker Press. Glomerular Glom. Filt. Rate Urine Volume Valve Status
(mm) (mm) (mm Hg) Press. (mm Hg) (ml/min) (ml)
0.50 0.45 70 49.72 58.57 161.76 open
0.50 0.45 80 52.40 91.78 186.23 open
0.50 0.45 90 55.08 124.99 200.44 open
0.50 0.45 100 57.76 158.20 209.72 open
0.50 0.45 70 49.72 58.57 161.76 open
0.50 0.45 70 49.72 26.94 0.00 closed
0.50 0.45 100 57.76 121.80 0.00 closed
0.50 0.45 100 57.76 158.20 209.72 open
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Post-lab Quiz Results
You scored 100% by answering 4 out of 4 questions correctly.
1. In humans, the glomerular filtration rate normally ranges from

You correctly answered: b. 80 to 140 ml/min.
2. Which of the following does not have a significant impact on the glomerular filtration rate?
You correctly answered: d. renal tubule length
3. In the absence of any regulatory mechanisms, what do you think would happen to the glomerular filtration rate of a
person who experiences an increase in blood pressure?
You correctly answered: a. The glomerular filtration rate could increase.
4. What would happen to the glomerular filtration rate of a person who experiences a large hemorrhage?
You correctly answered: b. The glomerular filtration rate would decrease.
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Review Sheet Results
1. As blood pressure increased, what happened to the glomerular capillary pressure and the glomerular filtration rate? How
well did the results compare with your prediction?
Your answer:
kami memperkirakan seiring dengan peningkatan tekanan darah, tekanan kapiler glomerulus dan laju filtrasi juga akan
meningkat. Hasilnya membenarkan prediksi kami karena semakin banyak darah yang masuk ke kapiler kapsul Bowman,
maka semakin tinggi tekanannya serta semakin meningkat pula laju filtrasi akibat tekanan yang tinggi. Ini selalu untuk
penyaringan darah lebih banyak.
2. Compare the urine volume in your baseline data with the urine volume as you increased the blood pressure. How did the
urine volume change?
Your answer:
Dilihat bahwa seiring dengan peningkatan tekanan darah, jumlah urin yang dihasilkan juga meningkat. Hal ini menunjukkan
bahwa tekanan glomerulus, laju filtrasi, dan jumlah urin semuanya akan meningkat karena setiap kali tekanan glomerulus
meningkat maka laju filtrasi harus meningkat sebanding dengan tingginya tekanan dan akhirnya laju filtrasi yang tinggi akan
menyebabkan peningkatan jumlah urin.
3. How could the change in urine volume with the increase in blood pressure be viewed as being beneficial to the body?
Your answer:
Peningkatan jumlah urin dapat bermanfaat bagi tubuh karena berarti limbah dikeluarkan dari tubuh lebih cepat dari
biasanya.Lebih sering buang air kecil menyebabkan dehidrasi, sehingga menyebabkan asupan cairan lebih banyak untuk
menggantikan cairan yang hilang saat buang air kecil. Hal ini juga meningkatkan jumlah urin, menciptakan siklus
penyaringan yang bermanfaat dengan konsumsi cairan yang cepat dan semakin cepat untuk menggantikan cairan yang
hilang.
4. When the one-way valve between the collecting duct and the urinary bladder was closed, what happened to the filtrate
pressure in Bowman's capsule (this is not directly measured in this experiment) and the glomerular filtration rate? How well
did the results compare with your prediction?
Your answer:
Setiap kali katup menutup, tekanan filtrasi tetap tidak berubah tetapi laju filtrasi glomerulus menurun. kami sebelumnya
memprediksi bahwa tekanan akan meningkat dan laju filtrasi akan menurun.Data menunjukkan bahwa tekanan glomerulus
sama dengan laju filtrasi ketika katup terbuka, sehingga menunjukkan bahwa tekanan tidak berpengaruh.Namun, data
menunjukkan bahwa laju filtrasi menurun setiap kali katup menutup, bukan membuka.Memang kandung kemih sudah
memiliki filtrat karena tidak ada aliran urin sehingga sistem tidak mampu melakukan filtrasi lebih lanjut.
5. How did increasing the blood pressure alter the results when the valve was closed?
Your answer:
Setiap kali tekanan darah meningkat ketika katup tertutup, hal ini terutama mempengaruhi laju filtrasi glomerulus. Laju
filtrasi glomerulus menurun karena tidak adanya keluaran urin. Laju filtrasi ini menurun karena tekanan glomerulus tetap
sama dan membebani sistem filtrasi sehingga menyebabkan laju filtrasi menjadi lebih lambat.
11/14/23 page 4

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Name: Kelompok 8

Pre-lab Quiz Results

1. Which of the following forces promotes filtration?

2. The glomerular filtration rate can be altered by

Stop & Think Questions:

What medical condition is analogous to the closed valve?

1. In humans, the glomerular filtration rate normally ranges from

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