University of Algiers 1

Science Faculty
Materials Science Department

Bachelor’s Degree
Pharmaceutical Chemistry
Analytical Chemistry

By Mr. Abdelghani Amaouche

Semester One - Year Three

2023/2024
 Analytical Chemistry
&
Pharmaceutical Chemistry
What is Analytical Chemistry?
What is Pharmaceutical Chemistry ?
 Analytical and pharmaceutical chemistry are two closely related fields that

play a vital role in modern science and medicine.

Analytical chemistry is the science of identifying and quantifying the components of matter.

It uses a variety of techniques, such as titration, spectrophotometry, and chromatography

to measure the concentration of substances in a sample.

On the other hand, pharmaceutical chemistry is the science of designing, synthesizing,

and testing drugs .

It uses the principles of analytical chemistry to measure the purity and potency of drugs,

as well as to monitor their metabolism in the body.

These interconnected fields are essential for understanding the natural

world and for developing new treatments for diseases.

 What is the difference between analytical
chemistry and pharmaceutical chemistry?

Analytical chemistry is the science of identifying and quantifying the components

of matter, while pharmaceutical chemistry is the science of designing, synthesizing,

and testing drugs. Analytical chemistry is used to understand the composition of

matter, while pharmaceutical chemistry is used to develop safe and effective drugs.
What are some of the techniques used in analytical
chemistry?

Some of the techniques used in analytical chemistry include titration,

spectrophotometry, and chromatography.

How does pharmaceutical chemistry use the
principles of analytical chemistry?

Pharmaceutical chemistry uses the principles of analytical chemistry to

measure the purity and potency of drugs, as well as to monitor their

metabolism in the body.

 What is the purpose of measuring the
concentration of substances in a sample?

The purpose of measuring the concentration of substances in a sample is to

determine the amount of a particular substance present in the sample.

 What are some of the things that pharmaceutical
chemists measure?

Some of the things that pharmaceutical chemists measure include the purity and

potency of drugs, the rate at which drugs are metabolized, and the effects of drugs

on cells and tissues.

Could you list the jargon-specific
terms employed in the text?
 Analytical and pharmaceutical chemistry are two closely related fields that

play a vital role in modern science and medicine.

Analytical chemistry is the science of identifying and quantifying the components of matter.

It uses a variety of techniques, such as titration, spectrophotometry, and

chromatography, to measure the concentration of substances in a sample.

On the other hand, pharmaceutical chemistry is the science of designing, synthesizing,

and testing drugs .

It uses the principles of analytical chemistry to measure the purity and potency of

drugs, as well as to monitor their metabolism in the body.

These interconnected fields are essential for understanding the natural

world and for developing new treatments for diseases.

Can you guess the meaning of the
terms you have listed?
 Components: The constituent parts of something.

Matter: Matter is anything that has mass and occupies space.

Titration: A chemical analysis technique used to determine the concentration of a solution

by slowly adding a known solution to it until a reaction endpoint is reached.

Spectrophotometry: A technique that measures the amount of light absorbed by

a solution at a specific wavelength, which can be used to determine the
concentration of a substance in the solution.

Chromatography: A technique used to separate and identify different components

in a mixture based on their interaction with a stationary phase and a mobile phase.

Concentration: The amount of a substance dissolved in a specific volume of solvent.

 Substances: Substances are any kind of matter that has a definite
composition and properties. They can be either pure or mixed.

Sample: A sample is a small amount of material that is representative of a larger whole. It is

used to make measurements or observations about the whole.

Synthesizing: Synthesizing is the process of creating a new substance by combining two or

more simpler substances. This can be done through chemical reactions or other processes.

Drugs: Substances that are used to treat or prevent diseases or to improve health.

Purity: The degree to which a substance is free from impurities.

Potency: The strength or effectiveness of a drug.

Metabolism: The chemical processes in living organisms that break down

and build up molecules to provide energy and maintain life.
Are there any words that have a similar
meaning to these specific terms?
 Word Synonyms

Components Parts,Elements, Ingredients

Matter Substance, Material, Stuff

Titration Titrimetry, Volumetric analysis

Spectrophotometry Absorptiometry, Spectrophotometric analysis

Concentration Strength, Density,

Chromatography Separation science, Separation technique

Substance Matter, Material, Stuff

 Word Synonyms

Sample Specimen, Example

Synthesizing Making, Creating, Manufacturing

Drug Medication, Medicine, Cure

Purity Cleanliness, Clarity

Potency Strength, Efficacy, Effectiveness

Metabolism Body Chemistry, Anabolism, Catabolism

Read the orginal text again.
 Original Text
Analytical and pharmaceutical chemistry are two closely related fields that

play a vital role in modern science and medicine. Analytical chemistry is the science of

identifying and quantifying the components of matter. It uses a variety of techniques, such as

titration, spectrophotometry, and chromatography to measure the concentration of

substances in a sample. On the other hand, pharmaceutical chemistry is the science of

designing, synthesizing, and testing drugs. It uses the principles of analytical chemistry to

measure the purity and potency of drugs, as well as to monitor their metabolism in the body.

These interconnected fields are essential for understanding the natural

world and for developing new treatments for diseases.

Read the following two texts
carfully.
 Text One

Analytical and pharmaceutical chemistry are intertwined disciplines crucial for scientific and

medical advancements. Analytical chemistry identifies and quantifies matter's components

using techniques like titration, spectrophotometry, and chromatography. Pharmaceutical

chemistry designs, synthesizes, and tests drugs, utilizing analytical chemistry principles to

assess drug purity, potency, and metabolism.

 Text Two
The fields of analytical and pharmaceutical chemistry are intimately linked and play a

pivotal role in the advancement of science and medicine. Analytical chemistry delves

into the identification and quantification of matter's components, employing techniques

such as titration, spectrophotometry, and chromatography to determine the

concentration of substances within a sample. Conversely, pharmaceutical chemistry

focuses on the design, synthesis, and evaluation of drugs, drawing upon the principles of

analytical chemistry to assess drug purity, potency, and metabolic behavior in the body.

These interconnected disciplines prove indispensable for understanding the natural

world and developing novel therapeutic interventions for dangerous diseases.

What are the key differences between
the original and the new versions?
 Do the texts contain any
unfamiliar or challenging words?
 Text One

Analytical and pharmaceutical chemistry are intertwined disciplines crucial for scientific

and medical advancements. Analytical chemistry identifies and quantifies matter's

components using techniques like titration, spectrophotometry, and chromatography.

Pharmaceutical chemistry designs, synthesizes, and tests drugs, utilizing analytical chemistry

principles to assess drug purity , potency, and metabolism.

 Text Two
The fields of analytical and pharmaceutical chemistry are intimately linked and play a pivotal

role in the advancement of science and medicine. Analytical chemistry delves into the

identification and quantification of matter's components, employing techniques such as titration,

spectrophotometry, and chromatography to determine the concentration of substances within a

sample. Conversely, pharmaceutical chemistry focuses on the design, synthesis, and evaluation

of drugs, drawing upon the principles of analytical chemistry to assess drug purity, potency,

and metabolic behavior in the body. These interconnected disciplines prove indispensable

for understanding the natural world and developing novel therapeutic interventions for

dangerous of diseases.
Upon comparing the two texts,
do you notice any points of
difference or dissimilarity?
What are the two texts called?
 Summary
Analytical and pharmaceutical chemistry are intertwined disciplines crucial for scientific and

medical advancements. Analytical chemistry identifies and quantifies matter's components

using techniques like titration, spectrophotometry, and chromatography. Pharmaceutical

chemistry designs, synthesizes, and tests drugs, utilizing analytical chemistry principles to

assess drug purity , potency, and metabolism.

 Paraphrase
The fields of analytical and pharmaceutical chemistry are intimately linked and play a

pivotal role in the advancement of science and medicine. Analytical chemistry delves into

the identification and quantification of matter's components, employing techniques such

as titration, spectrophotometry, and chromatography to determine the concentration of

substances within a sample. Conversely, pharmaceutical chemistry focuses on the design,

synthesis, and evaluation of drugs, drawing upon the principles of analytical chemistry to

assess drug purity, potency, and metabolic behavior in the body. These interconnected

disciplines prove indispensable for understanding the natural world and developing novel

therapeutic interventions for dangerous of diseases.

SUMMARIZING
 What is summarizing?

Summarizing is the process of identifying the main points of a text and

expressing them in a concise and abbreviated form. It involves understanding the

text, selecting the key information, and presenting it in a clear and organized way.

A summary is much shorter than a paraphrase.

 What are summarizing steps?
1-Read the text carefully
Make sure you understand the main ideas and supporting information.

2-Identify the main points.

These are the most imortant ideas that the author wants to convey. They are typically

found in the introduction, conclusion, and topic sentences of paragraphs.

3-Exclude unnecessary details

These are the least important information that can be left out without affecting the main

meaning of the text. They are found often in examples, explanations, and quotations.
 4-Organize the information.
Decide on the order in which you will present the main points. This could be

chronological order, order of importance, or order of complexity.

5-Express the information in your own words

Do not simply copy and paste from the original text. Instead, use your own words to

paraphrase the main points.

6-Use concise language

Get to the point and avoid unnecessary words or phrases.

7-Check for accuracy

Make sure that your summary accurately reflects the main ideas of the original text.
Summarizing techniques used in text one

Identifying the main points:

Analytical chemistry identifies and quantifies matter's components.

Pharmaceutical chemistry designs, synthesizes, and tests drugs.

 PRACTICE ONE

Summarize the original text.

PARAPHRASING
 What is paraphrasing?

Paraphrasing involves rephrasing someone else's ideas or information in your

own words while maintaining the original meaning. It's a crucial skill for anyone

who wants to avoid plagiarism and to ensure that they understand the source

material well enough to express it in their own way. A paraphrased text is

approximately the same length as the original.

 What are paraphrasing steps?
1-Read and understand the text
Carefully read the original text to fully grasp its meaning and identify the key points.

2-Set aside the original text

Once you have a good understanding of the text, put it aside and avoid

referring to it directly as you paraphrase.

3-Rephrase the text in your own words

Using your own vocabulary and sentence structures, rephrase the key points of the

original text.
 4-Maintain the original meaning
Ensure that your paraphrase accurately conveys the original meaning and

intention of the text. Avoid introducing new ideas or interpretations

5-Use synonyms and idioms

Replace words with synonyms or phrases that have similar meanings. Additionally,

use idioms that are appropriate to the context.

6-Vary the sentence structure

Break down long sentences into shorter ones and combine shorter sentences into

more complex ones to create a different rhythm

7-Check for accuracy

Once you've completed your paraphrase, compare it to the original text to ensure that you

haven't introduced any errors or misinterpretations..

 Remember, paraphrasing is not about simply
copying and pasting words or changing a few words

around. It's about understanding the original text and

expressing its meaning in your own way.

 Paraphrasing techniques used in text two
Using synonyms:

“Identify and quantify” is replaced with “delve into” in the paraphrase.

Changing sentence structure:

"Analytical chemistry uses a variety of techniques" is rephrased as "Analytical chemistry

employs techniques such as titration, spectrophotometry, and chromatography."

Adding examples or explanations:

"These interconnected fields are essential for understanding the natural world" is expanded

to "These interconnected disciplines prove indispensable for understanding the natural

world and developing novel therapeutic interventions for dangerous diseases."

 PRACTICE TWO

Paraphrase the original text.

 PRACTICE THREE

Summarize and paraphrase the following text using steps and techniques that

you have learned .

Artificial intelligence (AI) is transforming the drug discovery and development

process, making it faster, more efficient, and more effective. AI algorithms can

analyze massive amounts of data to identify potential drug candidates, predict

their properties, and design new compounds with improved efficacy and safety.

This technology is helping to accelerate the development of new treatments for a

wide range of diseases, including cancer, Alzheimer's disease, and HIV/AIDS."

 PRACTICE THREE

Summary Example
AI is revolutionizing drug discovery by analyzing vast amounts of data to identify

potential drug candidates, predict their properties, and design new compounds with

efficacy and safety, accelerating the development of treatments for various diseases.
 PRACTICE THREE

Paraphrase Example
The field of drug discovery is witnessing a remarkable transformation due to the arrival

of artificial intelligence. AI algorithms have the remarkable capability of analyzing

enormous datasets to find out potential drug candidates, estimate their characteristics,

and engineer novel compounds with superior efficacy and safety profiles. This

innovative technology is speeding up the development of new therapies for a lot of

conditions, including cancer, Alzheimer's disease, and HIV/AIDS.

 Discussion Topic
In your opinion, does artificial anteligence have a
positive impact on developing drug process and
treatments?