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    PhysioEx Exercise 9 Activity 3

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    t4gjzhpfjc
    The document summarizes the results of a PhysioEx lab report on the renal system's response to altered blood pressure. The student completed pre-lab and post-lab quizzes with 100% scores. During the experiment, the student varied the radii of the afferent and efferent arterioles under different blood pressure conditions and measured the effects on glomerular filtration rate and pressure. By dilating the afferent arteriole and constricting the efferent arteriole, the student was able to compensate for low blood pressure and maintain glomerular filtration near baseline levels, showing the kidney's ability to regulate filtration.

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    PhysioEx Exercise 9 Activity 3

    Uploaded by

    t4gjzhpfjc
    75 views4 pages
    The document summarizes the results of a PhysioEx lab report on the renal system's response to altered blood pressure. The student completed pre-lab and post-lab quizzes with 100% scores. During the experiment, the student varied the radii of the afferent and efferent arterioles under different blood pressure conditions and measured the effects on glomerular filtration rate and pressure. By dilating the afferent arteriole and constricting the efferent arteriole, the student was able to compensate for low blood pressure and maintain glomerular filtration near baseline levels, showing the kidney's ability to regulate filtration.

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    The document summarizes the results of a PhysioEx lab report on the renal system's response to altered blood pressure. The student completed pre-lab and post-lab quizzes with 100% scores. During the experiment, the student varied the radii of the afferent and efferent arterioles under different blood pressure conditions and measured the effects on glomerular filtration rate and pressure. By dilating the afferent arteriole and constricting the efferent arteriole, the student was able to compensate for low blood pressure and maintain glomerular filtration near baseline levels, showing the kidney's ability to regulate filtration.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    75 views4 pages

    PhysioEx Exercise 9 Activity 3

    Uploaded by

    t4gjzhpfjc
    The document summarizes the results of a PhysioEx lab report on the renal system's response to altered blood pressure. The student completed pre-lab and post-lab quizzes with 100% scores. During the experiment, the student varied the radii of the afferent and efferent arterioles under different blood pressure conditions and measured the effects on glomerular filtration rate and pressure. By dilating the afferent arteriole and constricting the efferent arteriole, the student was able to compensate for low blood pressure and maintain glomerular filtration near baseline levels, showing the kidney's ability to regulate filtration.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 4

    PhysioEx Lab Report

    Exercise 9: Renal System Physiology


    Activity 3: Renal Response to Altered Blood Pressure
    Name: Anushree Meru
    Date: 23 September 2023
    Session ID: session-5e8ee8d9-d52b-bff7-e515-ab7f8da168cf

    Pre-lab Quiz Results


    You scored 100% by answering 4 out of 4 questions correctly.

    1 If all other variables are kept constant, how does the afferent arteriole radius affect the
    rate of glomerular filtration?

    You correctly answered: An increased afferent arteriole radius will increase the rate of
    glomerular filtration.

    2 If all other variables are kept constant, how does the efferent arteriole radius affect the
    rate of glomerular filtration?

    You correctly answered: A decreased efferent arteriole radius will increase the rate of
    glomerular filtration.

    3 If all other variables are kept constant, how does blood pressure affect the rate of
    glomerular filtration?

    You correctly answered: Blood pressure directly affects glomerular filtration rate.

    4 In the absence of other renal processes (including tubular reabsorption and secretion),
    more glomerular filtration leads to a larger urine volume.

    You correctly answered: true.

    Experiment Results
    Predict Question
    1 Predict Question: What will happen to the glomerular capillary pressure rate and
    glomerular filtration rate if both of these arteriole radii changes are implemented
    simultaneously with the low blood pressure condition?

    Your answer: Glomerular filtration rate and pressure will rise above baseline values.
    Stop & Think Questions
    1 If blood pressure were to drop (for example, as the result of blood loss), what changes
    in the nephron would allow the kidney to maintain its normal glomerular filtration
    rate?

    You correctly answered: afferent arteriole dilation and efferent arteriole constriction.

    2 Comparing the glomerular filtration rate and glomerular capillary pressure with the
    baseline values (from the first run), how effective was the increased afferent arteriole
    radius in compensating for the low blood pressure?

    You correctly answered: The afferent arteriole dilation returned the low glomerular
    capillary pressure and filtration rate almost to baseline values.

    3 Comparing the glomerular filtration rate and glomerular capillary pressure with the
    baseline values (from the first run), how effective was the decreased efferent arteriole
    radius in compensating for the low blood pressure?

    You correctly answered: The efferent arteriole constriction improved the low
    glomerular capillary pressure and filtration rate marginally.

    Experiment Data
    Afferent Efferent Beaker Glomerular Glom. Filt. Urine
    Radius (mm) Radius Press. Press. (mm Hg) Rate Volume
    (mm) (mm Hg) (ml/min) (ml)
    0.50 0.45 90 55.08 124.99 200.44
    0.50 0.45 70 49.72 58.57 161.76
    0.60 0.45 70 54.25 114.72 196.72
    0.50 0.35 70 51.24 77.41 231.12
    0.60 0.35 70 55.58 131.15 245.57

    Post-lab Quiz Results


    You scored 100% by answering 4 out of 4 questions correctly.

    1 If all other variables are kept constant, when blood pressure decreases, glomerular
    filtration

    You correctly answered: decreases.

    2 If the efferent arteriole radius decreases in response to a decrease in blood pressure,


    then glomerular filtration
    You correctly answered: remains approximately the same.

    3 If all other variables are kept constant, when the efferent arteriole radius decreases,
    glomerular filtration

    You correctly answered: increases.

    4 With blood pressure held at a constant value, which of the following combinations will
    raise the glomerular filtration rate above baseline values?

    You correctly answered: afferent arteriole dilation and efferent arteriole constriction.

    Review Sheet Results


    1 List the several mechanisms you have explored that change the glomerular filtration
    rate. How does each mechanism specifically alter the glomerular filtration rate?

    Your answer:

    The afferent and efferent arterioles changes in radii had an effect on the
    glomerularfiltration rate because the arterioles control the blood pressure. Whenever
    the bloodpressure is increased due to the arterioles increasing in radius, the
    glomerular filtrationrate is increased as well.

    2 Describe and explain what happened to the glomerular capillary pressure and
    glomerular filtration rate when both arteriole radii changes were implemented
    simultaneously with the low blood pressure condition. How well did the results
    compare with your prediction?

    Your answer:

    The low blood pressure will result in a widening of the afferent arteriole to allow for
    theblood to flow easier, as well as a decrease in the efferent arteriole to slow the flow
    downout of the capsule. This allows for the glomerular filtration rate and glomerular
    capillarypressure to react normally without resulting in too high or too low of blood
    pressure.

    3 How could you adjust the afferent or efferent radius to compensate for the effect of
    reduced blood pressure on the glomerular filtration rate?

    Your answer:

    The afferent and efferent arteriole radius can be adjusted to compensate for the effect
    ofreduced blood pressure on the glomerular filtration rate because if it is dilated, that
    waymore blood can flow to the Bowman's capsule. The efferent arteriole radius can
    beconstricted, that way the blood is removed at a much low rate. Adjusting both the
    afferentand efferent arterioles will keep the glomerular filtration rate normal.

    4 Which arteriole radius adjustment was more effective at compensating for the effect of
    low blood pressure on the glomerular filtration rate? Explain why you think this
    difference occurs.

    Your answer:

    The afferent arteriole dilation is the most effective at compensating for the effect of
    lowblood pressure on the glomerular filtration rate. This adjustment is able to keep
    theglomerular filtration rate and blood pressure at normal values.

    5 In the body, how does a nephron maintain a near-constant glomerular filtration rate
    despite a constantly fluctuating blood pressure?

    Your answer:

    The nephron can maintain a near-constant glomerular filtration rate despite


    fluctuatingblood pressure because of its ability to dilated and constrict the afferent and
    efferentarteriole.

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