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    Drugstudy - Gorospe, Diana R.

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    Diana Gorospe
    Gentamicin is an aminoglycoside antibiotic used to treat various bacterial infections. It works by binding to negatively charged sites on bacterial cell membranes, disrupting the membrane integrity and inhibiting protein synthesis. The typical dosage is 35 mg every 12 hours intravenously. Contraindications include hypersensitivity, severe kidney impairment, or active herpes, vaccinia, or varicella infections. Adverse reactions include nephrotoxicity, ototoxicity, and neurotoxicity. Nursing responsibilities involve checking orders, educating the patient, monitoring for side effects like renal impairment, and documenting the administration and patient's condition.

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    Drugstudy - Gorospe, Diana R.

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    Diana Gorospe
    15 views2 pages
    Gentamicin is an aminoglycoside antibiotic used to treat various bacterial infections. It works by binding to negatively charged sites on bacterial cell membranes, disrupting the membrane integrity and inhibiting protein synthesis. The typical dosage is 35 mg every 12 hours intravenously. Contraindications include hypersensitivity, severe kidney impairment, or active herpes, vaccinia, or varicella infections. Adverse reactions include nephrotoxicity, ototoxicity, and neurotoxicity. Nursing responsibilities involve checking orders, educating the patient, monitoring for side effects like renal impairment, and documenting the administration and patient's condition.

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    Drugstudy_Gorospe, Diana R.

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    Gentamicin is an aminoglycoside antibiotic used to treat various bacterial infections. It works by binding to negatively charged sites on bacterial cell membranes, disrupting the membrane integrity and inhibiting protein synthesis. The typical dosage is 35 mg every 12 hours intravenously. Contraindications include hypersensitivity, severe kidney impairment, or active herpes, vaccinia, or varicella infections. Adverse reactions include nephrotoxicity, ototoxicity, and neurotoxicity. Nursing responsibilities involve checking orders, educating the patient, monitoring for side effects like renal impairment, and documenting the administration and patient's condition.

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    © All Rights Reserved
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    Download as docx, pdf, or txt
    15 views2 pages

    Drugstudy - Gorospe, Diana R.

    Uploaded by

    Diana Gorospe
    Gentamicin is an aminoglycoside antibiotic used to treat various bacterial infections. It works by binding to negatively charged sites on bacterial cell membranes, disrupting the membrane integrity and inhibiting protein synthesis. The typical dosage is 35 mg every 12 hours intravenously. Contraindications include hypersensitivity, severe kidney impairment, or active herpes, vaccinia, or varicella infections. Adverse reactions include nephrotoxicity, ototoxicity, and neurotoxicity. Nursing responsibilities involve checking orders, educating the patient, monitoring for side effects like renal impairment, and documenting the administration and patient's condition.

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    Gorospe, Diana R.

    BSN 2D
    St. James Hospital- NS2 December 3, 2023
    DRUGSTUDY

    NAME OF THE DRUG MECHANISM DOSAGE INDICATION CONTRAINDICATION ADVERSE REACTION NURSING RESPONSIBILITIES
    OF ACTION

    Generic Name: Binds to 35 mg Gentamicin is Contraindicated to CNS: Acute organic mental BEFORE:
    Gentamicin negatively q12. IV an antibiotic patient: syndrome, confusion,  Check doctor’s order
    charged sites used to treat  Hypersensitivity depression, fever, headache,  Take client’s RR, HR,
    Brand Name: on the outer various or serious toxic increased protein and temperature
    Garamycin, cell membrane bacterial reaction to other incerebrospinal fluid, lethargy,  Educate client about
    Cidomycin, Septopal of bacteria, infections. aminoglycosides. myasthenia gravis–like the drug, its purpose
    Classification: thereby These  with severe syndrome, neurotoxicity and importance
    Aminoglycoside disrupting the infections can kidney (dizziness, hearing loss, DURING:
    membrane’s affect various impairment or tinnitus, vertigo), peripheral  Give drug as exactly
    Route: integrity. parts of the those undergoing neuropathy or as prescribed
    IV Gentamicin body, such as dialysis may encephalopathy (muscle  Encourage adequate
    also binds to the urinary require dosage twitching, numbness, intake of fluid
    bacterial tract, adjustments or seizures, skin tingling), AFTER:
    ribosomal respiratory avoidance of pseudotumor cerebri  Document and
    subunits and tract, skin, gentamicin due to record
    inhibits bones, joints, the risk of CV: Hypertension,  Monitor patient for
    protein and more. worsening kidney hypotension, palpitations renal function
    synthesis. Both function. (creatinine levels)
    actions lead EENT: Blurred vision, and hearing status.
    to cell death. increased salivation, laryngeal  Take vital signs
    Precaution: edema, ototoxicity, stomatitis
    Use cautiously with renal vision changes
    or hepatic disease;
    preexisting hearing loss; GI: Anorexia, nausea,
    active infection with splenomegaly, transient
    herpes, vaccinia, hepatomegaly, vomiting
    varicella, fungal
    infections, mycobacterial GU: Nephrotoxicity
    infections (ophthalmic
    preparations); HEME: Anemia, eosinophilia,
    myasthenia gravis; granulocytopenia, increased
    parkinsonism; infant or decreased reticulocyte
    botulism; burn patients; count, leukopenia,
    lactation; pregnancy. thrombocytopenia

    MS: Arthralgia, leg cramps

    RESP: Pulmonary fibrosis,


    respiratory depression

    SKIN: Alopecia, generalized


    burning sensation, pruritus,
    purpura, rash, urticaria

    Other: Anaphylaxis, injection


    site pain, superinfection,
    weight loss

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