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Quetiapine

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DRUG STUDY

DRUG MECHANISM OF INDICATIONS CONTRAINDICATIONS SIDE EFFECTS/ ADVERSE NURSING


ACTION REACTIONS RESPONSIBILITIES
Generic Name Blocks dopamine and Major depressive Hypersensitivity. ADVERSE REACTIONS  Watch for evidence
Quetiapine serotonin 5-HT2 disorder, adjunctive CNS: dizziness, headache, of neuroleptic
receptors. Its action therapy. somnolence, neuroleptic malignant syndrome
Brand Name may be mediated malignant syndrome, seizures, (extrapyramidal
through this effects, hyperthermia,
Seroquel hypertonia, dysarthria, asthenia,
antagonism. autonomic
agitation. disturbance), which is
Classification CV: orthostatic hypotension, rare but deadly.
Antipsychotics: tachycardia, palpitations,  Monitor patient for
Dibenzothiazepine peripheral edema. tardive dyskinesia,
derivatives EENT: ear pain, pharyngitis, which may occur
rhinitis. after prolonged use.
Dosage GI: dry mouth, dyspepsia,  Hyperglycemia may
300 mg abdominal pain, constipation, occur in patients
nausea, anorexia, vomiting. taking drug.
Frequency Hematologic: leukopenia  Monitor patient for
weight gain.
Once a day Metabolic: weight gain,
 Monitor patient for
hyperglycemia. symptoms of
Route Musculoskeletal: back pain. metabolic syndrome.
Oral Respiratory: increased cough,  Drugs use may cause
dyspnea. cataract formation.
Skin: rash, diaphoresis.  Drugs may increase
Other: flulike syndrome. the risk of suicidal
thinking and
behavior.

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