Digestion

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Digestion

Monday, October 16, 2023


12:06 PM
What is digestion?

Breaking down of food into smaller components through the process of hydrolysis. It is necessary
because it is to acquire the different biomolecules in order to utilize and synthesize energy.

Two Kinds of Digestion

Mechanical Digestion - breaking down complex forms of food into simple forms of food; through the
action of the teeth by chewing, grinding and cutting.

Chemical Digestion - breaking down complex forms of food into simple forms of food through the aid of
enzymes and other fluids in the body. Breaking down of food is assisted by chemicals.

FACTORS THAT AID IN DIGESTION - allow food to be broken down while we consume food

DIGESTION

Mouth- where digestion occurs.

Saliva- facilitates swallowing, diluent for irritant substances


-mucin is found in the saliva; produced by glands on the face
-composed mostly of water; dilutes water you drink and consume in the mouth
-secretes salivary amylases (ptyalin) breaks down starch/carbohydrates.
-breaks down carbohydrates into dextrin and maltose

Gastric juice- consists of water and solid matter - has a pH 1-3


-breaks down proteins

Pancreatic juice - released by the pancreas.

Intestinal juice - it is produced and secreted in the intestines.


 Duodenum , jejunum, ileum produces these intestinal juice
 Enteropeptidase - lining of the small intestine releases trypsin, chymotrypsin, carboxypeptidase
are activated.
 The presence of this enzyme will activate the three enzymes
 Aminopeptidase - found in the microvilli
Dipeptidase - dipeptides
-nucleic acids

Intestinal juice neutralizes HCl


Bile - breaks down lipids through emulsification, dispersing of lipids in to the solution; it does not
dissolve
-breaks down fats, reacted by the bile and phospholipids allows small droplets to breakdown to form
miscells are absorbed by the microvilli. Forms into its triglyceride form
-allow absorption of fats in the small intestine

THE DIGESTION PROCESS

Anabolism - building up of complex molecules from simple ones


 Performed in the microvilli

Catabolism - breaking down of complex molecules to simple ones.


Ingestion - process of taking food in the mouth by swallowing
Mechanical digestion (mastication)
Chemical digestion (ptyalin)

Bolus- the slippery mass of partially broken-down food; mixture of food and saliva
Ideal times to chew food, 18 times

Passes down the esophagus

Esophageal peristalsis - sequential involuntary muscle contraction in the esophagus that pushes the
bolus down.

Esophageal sphincter - a muscular ring seals the esophagus from the stomach.

In the stomach - proteins are broken down into polypeptides by the action of the gastric juice.
Carbohydrates are partially broken down in the mouth
Lipids and Protein digestion starts in the stomach
Activates pepsinogen to pepsin
Chyme- secreted by the stomach

In the small intestine

Duodenum - pancreas secretes pancreatic juice


 Starch is further broken down into maltose (amylopsin) then into glucose (maltase)
 Gallbladder discharges bile to emulsify fats converts them into smaller globules.
 Other enzymes are lactase, sucrase and maltase

Jejunum and Ileum - absorption of nutrients and minerals in food take place through the villi and
microvilli - absorbed in the bloodstream
-types of transport mechanism - active transport, diffusion, facilitated diffusion, simple diffusion
-how each biomolecule is absorbed; glucose - active transport ; fructose - bloodstream assisted by
facilitated diffusion; gluc2 - all of the carbs, gluc 5 - glucose, ngl-t1 - fructose
Biomolecule that cannot be carried to the blood capillaries - Lipids
Lipids are carried to the lacteal- enters through the lacteal

 Iron is absorbed in the duodenum


 Vitamin B12 and bile salts are absorbed in the terminal Ileum.
 Water and lipids are absorbed by passive diffusion throughout the small intestine; water and
salts absorbed in the large intestine
 Sodium bicarbonate is absorbed by amino acid co-transport
 Fructose is absorbed by facilitated diffusion

In the large intestine to the anus


 Absorption of water from undigested food take place and convert them to stool
 It is stored in the rectum until it is eliminated through the anus via defecation.
 Eliminated through the anus.

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