Calamba Doctors' College: Digestion, Absorption, and Metabolism Lesson 5
Calamba Doctors' College: Digestion, Absorption, and Metabolism Lesson 5
Calamba Doctors' College: Digestion, Absorption, and Metabolism Lesson 5
Lecture 3
Lesson 5
The foods eaten undergo digestion, absorption and utilization. Metabolism refers to the chemical processes that
occur inside the cells as they transform nutrients into energy and body tissue. The transformation of foods into various
nutrients like carbohydrates, fats, and protein and other physiological processes are parts of the metabolic processes.
Objectives
1. To describe how foods are digested and transformed through the body
2. To identify the roles of the various digestive organs
3. To discuss how nutrients are utilized in the body
Lessons
1. The digestive organs
2. How food moves through the body
3. How nutrients are absorbed and pass along the body
Definition
Digestion – the process by which food is broken down in the gastrointestinal tract to release nutrients in forms
that the body can absorb.
Absorption - the process by which nutrients are taken into the cells that line the gastrointestinal tract.
Transport the movement of nutrients through the circulatory system from one area of the body to another.
Metabolism the sum of the vast numberof chemical changes in the cell that ultimately produce the materials
that are essential for energy, tissue building, and metabolic controls.
The appetizing sight and smell of food stimulate the digestive organs into action. The mouth waters, the
stomach contracts. Intestinal glands begin to secrete the chemicals that will act on food and break them into simple
substances.
The digestive system has the ability to turn complex food into basic nutrients. This requires a group of digestive
organs, each designed specifically to perform one role in the process. The digestive system is a long tube that starts at
the mouth, continuous down through the throat, to the stomach, and then to the small and large intestine and past the
rectum to end at the anus.
In between, with the help of the liver, pancreas, and gallbladder, the digestible parts of everything eaten are
converted to simple substances that the body can easily absorb to burn for energy or build new tissue form. The
indigestible residue is bundled off and eliminated as waste.
Chemical digestion occurs at every point in the digestive tract where enzymes and other substances such as
hydrochloric acid (from stomach glands) and bile (from the gallbladder) dissolve food, releasing the nutrients contained.
Sites of secretion and absorption in the gastrointestinal tract
Each organ in the digestive system plays a specific role in the digestive process. The first act occurs in two places
that are never listed as part of the digestive tract: the eyes and nose.
The mouth
Food is lifted and put into the mouth and the teeth and salivary glands swing into action. The teeth chew,
grinding the food, breaking it into small, manageable pieces. As a result:
The food (bolus) can be swallowed without choking.
The indigestible sheath of fiber surrounding the edible parts of some foods is brokendown so that the digestive
enzymes can get to the nutrients inside.
At the same time the salivary glands under the tongue and in the back of the tongue secrete the watery liquid
called saliva, which performs two important functions:
Moistens and compacts food so that the tongue can push it to the back of the mouthsending the food down into
the esophagus and into the stomach.
Provides amylases, enzymes that start the digestion of complex carbohydrates, breakingthe starch molecules
into simple sugars. No protein or fat digestion occurs in the mouth.
The Stomach
The stomach is pouchy part just below the esophagus that holds the chewed food. Like most of the digestive
tube, the stomach is circled with strong muscles whose rhythmic contractions - called peristalsis – move food along and
turn the stomach into a sort of food processor that mechanically breaks pieces of food into even smaller particles.
While this is going on, glands in the stomach wall are secreting stomach juices – a potent blend of enzymes,
hydrochloric acid, and mucus. Hydrochloric acid activate release of pepsin enzymes for partial digestion of protein
Other enzymes, plus stomach juices, begin the digestion of protein and fats, separating these into its basic components
– amino acids and fatty acids.
After every useful, digestible ingredient other than water has been wrung out of the food, the rest – indigestible
waste such as fiber – moves to the top of the large intestine, the area known as the colon. The colon’s primary job is to
absorb water from this mixture and then to squeeze the remaining matter into the compact bundle known as feces.
Feces (whose brown color comes from leftover bile pigments) are made up of indigestible material from food, plus cells
that have sloughed off the intestinal lining and bacteria. In fact about 30 percent of the entire weight of the feces is
bacteria.
Absorption
When digestion is complete, carbohydrate reduced to simple sugars glucose, fructose, and galactose, fats into
fatty acids and glycerides and protein into single amino acids. And vitamins and minerals are liberated. With a water
base for solution and transport
Large Intestine
Metabolism
Metabolism is the sum of the chemical reactions that occur within a living cell to maintain life. The
mitochondrion of the cell is the work center in which all metabolic reactions take place.
Metabolism – process where nutrients are change into energy
1. Aerobic metabolism – nutrients are combine with oxygen within the cells this process called oxidation
Carbohydrates (CHO) reduce to carbon dioxide and water
Protein (C2H4O2N) reduce to carbon dioxide, water and nitrogen
2. Anaerobic metabolism – reduced fat without the use of oxygen
Krebs cycle – complete oxidation of carbohydrate, protein and fats
Types of Metabolism
1. Catabolism is the breaking down of large substances into smaller units. For example, breaking down stored
glycogen into its smaller building blocks (i.e., glucose) is a catabolic reaction.
2. Anabolism is the process by which cells build large substances from smaller particles, such as building a complex
protein from single amino acids.
Objectives
Describe the function and general recommendations for carbohydrate, protein, and fat in health promotion,
prevention and disease management.
Differentiate water-soluble from fat soluble vitamins
Recognize the function and food sources of each of the vitamin and minerals
Describe the importance of water and explain the appropriate intake in the diet.
Lesson
Macronutrients
Micronutrients
Essential Nutrients
Carbohydrates
Primary source of energy (energy foods).
Name for chemical elements composed of carbon, hydrogen, and oxygen.
Functions
o Providing energy (4 calories/gram),
o Protien sparing action
o Normal fat metabolism
o Providing fiber.
Sources - plant foods - cereal grains, vegetables, fruit, and sugar, animal source – milk.
Dietary Requirement: The dietary requirement for carbohydrates is 50%-60% of recommended calorie
intake/day (250 gm/day).
Depletion of glycogen store or with fasting cause ketoacidosis (need 50 -100 mg each day)
Classification
1. Monosaccharides ((C6H12O2)single sugars) – The simpliest form of CHO, they are sweet, require no digestion and
absorbed directly into the blood stream from small intestine.
A. Glucose (dextrose) –Most cells depends on glucose as fuel. Brain cell and nervous system depend exclusively
on glucose.
Sources are berries, corn syrup, grapes, sweet corn
B. Fructose (levulose or fruit sugar) – found with glucose in many fruits, the sweetest of all monosaccharides,
Sources are ripe fruits, honey, soft drinks.
C. Galactose – occurs mostly as part of lactose, a disaccharide also known as milk sugar. During digestion,
galactose is freed as a single sugar
Food Sources
Animal source (non-visible fat) – meat, milk, egg yolk, fish
Plant source (visible fat)– cooking oil.
Dietary Requirement - 20%-30%, approximately 50gms in 2200 kcal (US – 33-36% RDA), Linoleic acid 2%,
Polyunsaturated 10%, monounsaturated 10%, and saturated fatty acid 10% ( US- saturated is 7%, polysaturated is 8%,
monosaturated is 15%), 30-50 gm fat is considered low fat diet.
Classification
1. Triglycerides – 3 fatty acid attached to glycerol
Glycerol – water soluble carbohydrates
Fatty acid – are organic compound of carbon atom attached to hydrogen atom
Fatty acids - are the building blocks of triglycerides can be classified by their length as short-, medium-, or long-
chain fatty acids
2. Phospholipid – are derivatives of phosphatide acid, or as triglyceride modified to contain phoshate group.
Phospholipid act as emulsifiers in the body, helping to keep other fats in solution in the watery blood and body
fluids
o Lecithin – a fatty substance classified as phospholipid both found in animal and plant. Help transport fat
in blood stream, and help prevent cardiovascular disease
3. Sterol
Sterols are a subgroup of steroids, and they are amphipathic in nature. Sterols made by plants are called
phytosterols, and sterols produced by animals are called zoosterols.
Cholesterol is the most familiar sterol, It is not true fat but a fat like substance (exogenous cholesterol –
animal food, endogenous – body cell). For synthesis of bile, sex hormone, cortisone, and Vitamin D, the body
manufacture 800-1000 mg/day. normal serum level = < 200 mg/day, normal daily requirement = 300 mg,
sources - egg yolk, fatty meat, shellfish, butter, cheese, whole milk and meat organ.
4. Hydrogenation
Hydrogenation is a chemical process by which hydrogen atoms are added to monounsaturated or
polyunsaturated fats to reduce the number of double bonds. A disadvantage is that hydrogenation makes
polyunsaturated fats more saturated
o Trans-fatty acid - The one made from hydrogenation of polyunsaturated fats which change liquid to
solid fats. Can cause or a risk factor for cadiovascular diseases and TFA cause LDL and Total cholesterol
to increased
5. Lipoproteins
Protein combined with the product of digestion fats which carry fats to the body by way of the blood.
Lipoproteins are the major vehicles for lipid transport in the bloodstream, are combinations of triglycerides,
protein, phospholipids, cholesterol, and other fat-soluble substances
Classification
1. Chylomicrons – first lipoprotien identified after eating
2. Very low density lipoprotien – made from the liver who carry triglycerides
3. Low density lipoprotien – carry trigycirides and chlolesterol fro liver to the cell
4. High density lipoprotien – carry chlolesterol from cell to liver for excretion
Protein
Proteios meaning “to hold first place” or “prime importance
The word is use due to its’ function of building and repairing cell.
Life process defends on protiens
The basic material of every body cells.
Chemical Nature
C2 H4 O2 N = Carbon, Hydrogen, Oxygen, Nitrogen
Amino Acid = The building block of protein.
Functions
1. Building and repairing body tissue (Protein balance)
Catabolism – cell are brocken down.
Anabolism – repair other tissue.
2. Regulating body function
Component of hormone and enzyme which is essential for digestion, metabolism, fluid and electrolyte
balance,
Essential in development of antibodies and immune system.
3. Providing energy
4 kcal each gram
Food Sources
Animal food: provide high quality and complete protein, Complete protein contain all the essential amino acid in
sufficient amount for growth and maintenance of life.
Plant food: are sources of partial and incomplete protein. Partial complete protein can maintain life but do not
support growth like wheat, legume. Incomplete protein can’t support life and growth like corn, gelatin,
Dietary Requirement:
Protein requirement is determine by size, age, sex and physical activity. Need more protein for growing child,
pregnant women, breastfeeding mother, extra protein for surgery, burn, and during infection. Adult daily requirement is
0.8 - 0.9 gram of protein for each kilogram (US standard), (Philippine standard infant = 1.5 gm/kg, toddler – preschooler=
2.15gm-2.0gm, school age = 1.8gm-1.6gm, adolescent = 1.6gm-1.3gm, and above 19 year = 1 gm – 1.14 gm for each kg)
Nitrogen Balance
The body’s nitrogen balance indicates how well its tissues are being maintained. The intake and use of dietary
protein are measured by the amount of nitrogen supplied by food protein and the amount of nitrogen excreted in the
urine, feces and sweat. When nitrogen intake equals nitrogen output, a person is in nitrogen equilibrium, or zero
nitrogen balance.
Positive nitrogen balance - nitrogen intake exceeds than nitrogen output as in growing infants, children, and
adolescents , pregnant women; and people recovering from protein deficiency or illness;
Negative nitogen balane - nitrogen output exceeds their nitrogen intake as seen in people who are starving or
suffering from severe stresses such as burns, injuries, infections, and fever
Protein Malnutrition
Protein-energy malnutrition (PEM ) – described condition develops when the diet delivers too little protein, too
little energy, or both. Children are at the highest risk for experiencing malnutrition because of their high needs during
rapid growth and development
Early signs are weakness, weight loss, reduce resistance to infection, lethargic and pallor, Late signs are edema,
dry and scaly skin. (Growth retardation in children), liver is enlarged.
Form Protein energy malnutrition (PEM)
1. Marasmus – severe malnutrition, hair is dull, thin skin, old man’s face (wrinkled), thin muscle, thin fat, very
underweight. (chronic form of energy and protein deficiency)
2. Kwashiorkor – Present of edema, some adipose tissue left, enlarge abdomen, weight loss is not significant
(common in ages of 18 and 24 months)
Kwashiorkor is a Ghanaian word meaning a “sickness that infects the first child when the second child is
born.”
Activity No: 3
Name: ___________________________ Date: ____________________
Year and Section: __________________
Multiple Choice: Encircle the letter that corresponds to the correct answer
1. Mr. X 20 year old was brought to hospital with second degree burn and affecting 40% of his body surface then
he was admitted to burn unit. Upon admission Mr X would most likely be in a state of:
A. Glycolysis C. Positive nitrogen balance
B. Catabolism D. Anabolism
2. This is a chemical digestion secreted that in the mouth.
A. Mucus C. Options A and B are correct
Meal Planning
Direction: Design a meal plan for individual base on their nutritional requirements
Carbohydrate diet – Meal for client frequently vomit with lack of appetite
Meal Pattern Sample Menu (Food)
Meat/Fish/Poultry
Rice/Bread
Vegetables
Fruit/Dessert
Soup
Beverage/Drinks
Fat diet – Meal for client who is overweight and diagnosed with diabetes
Meal Pattern Sample Menu (Food)
Meat/Fish/Poultry
Rice/Bread
Vegetables
Fruit/Dessert
Soup
Beverage/Drinks
Protein diet – Meal for client requiring enough protein but his/her budget for food is limited
Meal Pattern Sample Menu (Food)
Meat/Fish/Poultry
Rice/Bread
Vegetables
Fruit/Dessert
Soup
Beverage/Drinks
CALAMBA DOCTORS’ COLLEGE
Virborough Subdivision, Parian, Calamba City, Laguna
Objectives:
1. To make a meal plan for individual requiring modification in carbohydrates, fats and protein
2. To discuss diet plan and its implication for certain disease condition or situation
Case 2: Prepare a diet plan for client who is suffering from acute kidney disease. Calculate and prepare a low protein diet
meal (10% less) using 2000 Kcal. Prepare a 1 sample menu plan and discuss it base on client’s needs.(For Surname start
with letter D – M)
Case 2: Prepare a diet plan for client who is suffering from obesity. Calculate and prepare a low fat diet meal (25 % less)
using 2000 Kcal. Prepare a 1 sample menu plan and discuss it base on client’s condition (For surname start with letter N
– Z)
Meal ___________________
Meal Pattern Sample Menu
Meat/Fish/Poultry
Rice/Bread
Vegetables
Fruit/Dessert
Soup
Beverage/Drinks
Question for Discussion
1. What are the purposes or benefits of your menu according to client condition?