Biguanides

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Drug name Classification of Mechanism route Timing Adverse effect Nursing

drug of action considerations


Biguanides Biguanides Biguanides Oral Biguanides biguanides is -Monitor
decrease work in the are gastrointestinal blood glucose
hepatic glucose following available distress, levels as
production— ways: They as liquid, including ordered to
both reduce the tablets, diarrhea, evaluate
gluconeogenesis production and cramps, effectiveness
and of glucose extended- nausea, of drug and
glycogenolysis— during release vomiting, and glycemic
to lower plasma digestion (long- increased control.
glucose. They by acting) flatulence [72]. -Monitor
are classified as decreasing tablets. Long-term use results of
peripheral the amount The liquid of biguanides laboratory
insulin of glucose is taken has been tests,
sensitizers. absorbed with meals associated with including
from the one or two decreased urinalysis, for
food. They times a absorption of evidence of
prevent the day. The vitamin B12 glycosuria,
liver from regular and renal and
converting tablet is liver function
fats and taken with tests, to
amino meals two determine the
acids into or three need for
glucose. times a possible dose
They day, and adjustment
increase the and evaluate
the extended- for signs of
excretion release toxicity.
of sugar by tablet is
the kidneys taken once
daily with
the
evening
mea

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