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    Expt1 - Nikhil Bhardwaj - 200633 - D7

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    Nikhil Bhardwaj
    This 3-page document describes the synthesis of aspirin (acetylsalicylic acid) from salicylic acid. Key steps include: 1) Dissolving salicylic acid in sulfuric acid and adding acetic anhydride. 2) Isolating the product via filtration and recrystallization in ethanol. 3) Obtaining purified aspirin crystals with a 51.66% yield and melting point of 134-136°C, consistent with aspirin. 4) Confirming the absence of phenolic groups via Fehling's test.

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    Expt1 - Nikhil Bhardwaj - 200633 - D7

    Uploaded by

    Nikhil Bhardwaj
    29 views6 pages
    This 3-page document describes the synthesis of aspirin (acetylsalicylic acid) from salicylic acid. Key steps include: 1) Dissolving salicylic acid in sulfuric acid and adding acetic anhydride. 2) Isolating the product via filtration and recrystallization in ethanol. 3) Obtaining purified aspirin crystals with a 51.66% yield and melting point of 134-136°C, consistent with aspirin. 4) Confirming the absence of phenolic groups via Fehling's test.

    Original Description:

    Experiment 1

    Original Title

    EXPT1_NIKHIL BHARDWAJ_200633_D7

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    This 3-page document describes the synthesis of aspirin (acetylsalicylic acid) from salicylic acid. Key steps include: 1) Dissolving salicylic acid in sulfuric acid and adding acetic anhydride. 2) Isolating the product via filtration and recrystallization in ethanol. 3) Obtaining purified aspirin crystals with a 51.66% yield and melting point of 134-136°C, consistent with aspirin. 4) Confirming the absence of phenolic groups via Fehling's test.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    29 views6 pages

    Expt1 - Nikhil Bhardwaj - 200633 - D7

    Uploaded by

    Nikhil Bhardwaj
    This 3-page document describes the synthesis of aspirin (acetylsalicylic acid) from salicylic acid. Key steps include: 1) Dissolving salicylic acid in sulfuric acid and adding acetic anhydride. 2) Isolating the product via filtration and recrystallization in ethanol. 3) Obtaining purified aspirin crystals with a 51.66% yield and melting point of 134-136°C, consistent with aspirin. 4) Confirming the absence of phenolic groups via Fehling's test.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
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    of 6

    ENperiment Name /No.

    :
    Bynthe8is0 Asphun amlin Page No. 1
    Date of O4I 2021
    Aim AynthesuS oAShin

    Aaratus Required Cenical tlask, blas hod, beake.


    measutung cylincle and ofhetgental afparats
    Chenucals Requireo daliayuc acid, bulphuuc acid
    Hhanet, Methanel,Acektc anhydiud and Fehtuc
    LChleude

    Peineihal Felic
    HemanA in 1817attemfuking
    to nd a vcdug to ease hu truthes i
    athitus uithout
    taustng hebevere tmach
    Urutatio, asociatesl utm he standaAd ant
    athsuties diugsc that Hme, bocliwmn
    halicytate Cause the ds coveyo
    Ain
    H nam Afin beteved to Jse clotir ed
    ne A o Acet and shir e
    Shirea he botomicalvame th
    meadou8 weat plant rom thich balicylic
    aad Lwag
    vst vchemically isolated
    Ahsin On e the oldest amel met
    JMBeul dug nown. alucylates ahe ant'
    yhettes é hey lowe the body
    temhsetu COhe2 who has eve Aut
    itle etect a he AemhaOtu natma
    ali ctate also LOld avalgenc, whuch
    elieves Cctain yhe hain

    30

    Teacher's Signature:
    o

    OH

    stutin -aLetoxy benzoic acid


    oH

    O c
    C-OH H

    oH
    Ashin
    CH,-C-OH
    6alicc tud

    A - O-H
    7oH

    :
    C
    o-H
    CH - C

    + H
    H
    CHCOoH
    OH
    OH2 13
    I1CO eH 2
    Fe
    coOH t -2H
    D'IFe.
    oH
    - o

    son
    ot oH
    Calculateyns
    Moles Daluey cluc acid 2 . 0 o oI4Y moles
    138.12
    Hence, moleS e Acetto Anhydride o. 0144X 2.7 o.o 38
    (nam5 Acetc anhydude 0 - 0 388 X 102 - 08 g/mol
    3.16
    Volume Acettc Anhydrudla 3.96 3.4 mi
    1.c8

    Theeuucal yeild= 0.ol4 4 moles -2-594 gn ot


    auet c Saly ycue a

    hercentag e yreld = 34 x loo

    2 534
    Sl.66 .
    arTe/ Mo, Camlin Pago No.
    fi
    petitrent
    Date

    Poceduwo

    ) Taxe
    lake) Laicyuc aud ane l'tonsjer it Lnto a
    I50 m dy onucal ftask

    ad2 Sauvalent eh acehc antydraide ( 3.67 m)


    neazuing ytinder to h e 2inyic acid
    Loyaurirgontal laxk Now add 5- d n
    chLcnt. H,S04 to t h
    Hask d tih
    ll the
    balicyiicacid disclved
    eave the enckn mixu wndistubed l e
    -20 ninut04

    me uoue to he Hask and_&ue


    mirue uand filie LUSinga uenoL

    nn

    e th old Suoduct om the kilte

    d2iee h uude fnduct fn ml o ethanol


    dutMled unte tleat on
    add 1Srnl
    uwntes. lyoth tl ya et a clea Soluuttom

    toCopt in La c e bath
    )ALow the soutlon
    withoutdistubtvg

    TeachersSignature
    Experiment Name / No.:.
    Synthest o Ashin Camlin |Page No. 2
    Date ofl OyI 202

    S)ilte the w hsoduct amd dlAy u


    lacngin betuscon neets the
    ahes Kenett the- k
    hescennge yield
    Qissolue aeu Cuystals the d u comhoud
    n 0.5 m methame
    and add uanaA
    feclzsalutin Note_ the csl
    chang
    Keheit he Laleove test_ ui th
    Salioyic acid bimila amount
    amd note he tolei change
    1o eteamine the meltna
    Aid oint eky Salicytic

    ObelkVatim
    weghtk ur Cuystascbtaineo 1.34
    tex addition methanntuanel teckz ceer
    olution uesnained ight ellow

    Resulk

    pecentage yield A 51. 66 .

    Meltina pint Lo acetyl Aalicylic a c i d


    134 136 C

    Teacher's Signature-
    Experiment Name / No:`yntheAs a %in Camlin p 3
    Date1 0 4 | 2024

    Foclg
    Feclg test tonirms the absenc o phenduicgk0uh
    n acetai dalicyic Lacid.

    Acekglsaliquclic acid uas ynthesized om altul


    ud

    ecaukiama
    ake h Aalicylic aud in dk conical laak
    Conc HaSo &haulsl se handled uih caks
    3Cybtal hould loegEntly dRied

    Teacher's Signature
    3O

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