Drugs
Drugs
Drugs
DRUG STUDY
Name of Drug Special Indication Nursing Responsibility
Mechanism of Action (Relate it to
(Generic Name / (Based on patients (Based on drug’s
patient’s problem)
Brand Name) Problem) physiologic effects)
Folic Acid - Folate - Required for nucleoprotein - Remain under
Deficiency synthesis and the close medical
- Hemolytic maintenance of normal supervision
Anemia erythropoiesis. while taking
folic acid
therapy.
Tranexamic Acid - Treatment of - A synthetic derivative of - Monitor blood
cyclic heavy the amino acid lysine and pressure,
menstrual binds the 5 lysine binding pulse, and
bleeding in sites on plasminogen. This respiratory
premenopausal inhibits plasmin formation status as
females. and displaces plasminogen indicated by
from the fibrin surface. severity of
bleeding.
Feosol - used for the - helps your blood carry - Monitor Hgb
prevention and oxygen to tissues and and
treatment of organs and helps your reticulocyte
iron deficiency muscle cells store oxygen. values during
anemia. therapy.
Lactulose - used as a - decreasing the intestinal - Diarrhea may
laxative in the production and absorption indicate the
treatment of of ammonia. dose is too
chronic high.
constipation in
adults and
geriatric
patients.
Vitamin B - help prevent - act as coenzymes in a - Assess patient
Complex infections and substantial proportion of for signs of
help support or the enzymatic processes vitamin
promote that underpin every aspect deficiency
growth of red of cellular physiological before and
blood cells. functioning. periodically
during
therapy.
Furosemide - treatment of - works by blocking the - Monitor
edema absorption of sodium, weight, intake,
associated chloride, and water from output, and
with cirrhosis the filtered fluid in the serum
of the liver. kidney tubules, causing a electrolyte
profound increase in the levels.
output of urine
Spironolactone - management - acting primarily through - Give daily
1
of edema in competitive binding of doses early so
cirrhotic adults receptors at the that increased
not responsive aldosterone-dependent urination does
to fluid and sodium-potassium not interfere
sodium exchange site in the distal with sleep.
restrictions convoluted renal tubule.
Zinc Sulfate - used to - inhibits cAMP-induced, - Monitor
replenish low chloride-dependent fluid progression of
levels of zinc secretion by inhibiting zinc
or prevent zinc basolateral potassium (K) deficiency
deficiency, or channels. symptoms
to test for zinc during
deficiency. therapy.
Bumetanide - treatment of - inhibiting reabsorption of - Give single
edema sodium and chloride dose early in
associated through interference with day so
with hepatic the chloride-binding increased
and renal cotransport system urination will
disease. not disturb
sleep.
Propranolol - to treat - Competitively blocks both - Report
hypertension. β1 and β2 adrenergic immediately
receptors. an unusually
slow heart rate
or signs of
other
arrhythmias.
Metolazone - treatment of - works by inhibiting sodium - Monitor signs
salt and water transport across the of fluid,
retention. epithelium of the renal electrolyte, or
tubules, resulting in a acid-base
decrease in sodium imbalances,
reabsorption and an including
increase in sodium, dizziness,
chloride, and water drowsiness.
excretion.
2
Roa
DRUG STUDY
Name of Drug Special Indication Nursing Responsibility
Mechanism of Action (Relate it to
(Generic Name / (Based on patients (Based on drug’s
patient’s problem)
Brand Name) Problem) physiologic effects)
Folic Acid - Hemolytic - Required for nucleoprotein - Remain under
Anemia synthesis and the close medical
maintenance of normal supervision
erythropoiesis. while taking
folic acid
therapy.
Omeprazole - indicated for - suppresses stomach acid - Instruct
gastric ulcers secretion by specific patient to
inhibition of the H+/K+- report
ATPase system found at the bothersome or
secretory surface of gastric prolonged side
parietal cells effects
Vitamin B - help prevent - act as coenzymes in a - Assess patient
Complex infections and substantial proportion of for signs of
help support or the enzymatic processes vitamin
promote that underpin every aspect deficiency
growth of red of cellular physiological before and
blood cells. functioning. periodically
during
therapy.
Amlodipine - to lower blood - works by blocking the - Report any
pressure voltage-dependent L-type rhythm
calcium channels, thereby disturbances
inhibiting the initial influx or symptoms
of calcium. of increased
arrhythmias.
Sucralfate - to treat and - It dissociates in the acid - Give drug on
prevent environment of the stomach an empty
duodenal to its anionic form, which stomach, 1 hr
ulcers binds to the ulcer base. before or 2 hr
after meals
and at
bedtime.
3
Guibone
DRUG STUDY
Name of Drug Special Indication Nursing Responsibility
Mechanism of Action (Relate it to
(Generic Name / (Based on patients (Based on drug’s
patient’s problem)
Brand Name) Problem) physiologic effects)
N - Acetylcysteine - improves - enhances sulfate - Monitor other
oxidative conjugation of signs of
stress and unmetabolized APAP, allergic
inflammatory functions as an anti- reactions and
response in inflammatory and anaphylaxis.
patients with antioxidant, and has
community positive inotropic effects
acquired
pneumonia.
Levofloxacin - used to treat - a bactericidal antibiotic of - Monitor signs
bacterial the fluoroquinolone drug of
infections in class that directly inhibits pseudomembr
many different bacterial DNA synthesis. anous colitis,
parts of the including
body. diarrhea,
abdominal
pain, fever,
pus or mucus
in stools, and
other severe
or prolonged
GI problems
Lactulose - used as a - decreasing the intestinal - Diarrhea may
laxative in the production and absorption indicate the
treatment of of ammonia. dose is too
chronic high.
constipation in
adults and
geriatric
patients.
Paracetamol - reduces fever - reduces fever by affecting - Do not take
the chemical messengers in other
an area of the brain that medications
regulates body temperature. containing
acetaminophe
n without
medical
advice.
4
Paclar
DRUG STUDY
Name of Drug Special Indication Nursing Responsibility
Mechanism of Action (Relate it to
(Generic Name / (Based on patients (Based on drug’s
patient’s problem)
Brand Name) Problem) physiologic effects)
Omeprazole - indicated for - suppresses stomach acid - Instruct
gastric ulcers secretion by specific patient to
inhibition of the H+/K+- report
ATPase system found at the bothersome or
secretory surface of gastric prolonged side
parietal cells effects
Folic Acid - Hemolytic - Required for nucleoprotein - Remain under
Anemia synthesis and the close medical
maintenance of normal supervision
erythropoiesis. while taking
folic acid
therapy.
NahCO3 – Sodium - used as an - main therapeutic effect of - Assess the
Bicarbonate antacid to treat sodium bicarbonate client's fluid
heartburn, administration is increasing balance
indigestion, plasma bicarbonate levels, throughout the
and upset thereby raising solution pH therapy.
stomach. to combat clinical
manifestations of acidosis
Clonidine - used to treat - stimulates alpha- - Monitor blood
hypertension adrenoceptors in the brain pressure and
stem. pulse rate
frequently.
5
Caspe
DRUG STUDY
Name of Drug Special Indication Nursing Responsibility
Mechanism of Action (Relate it to
(Generic Name / (Based on patients (Based on drug’s
patient’s problem)
Brand Name) Problem) physiologic effects)
Tramadol - Indicated for - Tramadol modulates the - Monitor
moderate to descending pain pathways changes in
severe pain within the central nervous mood such as:
system through the binding confusion,
of parent and M1 malaise.
metabolite to μ- opioid -
receptors and the weak
inhibition of the reuptake of
norepinephrine and
serotonin.
Enoxaparin - Indicated for - acts mainly by accelerating - Assess for
the prevention the rate of the signs of
of ischemic neutralization of certain bleeding and
complications activated coagulation hemorrhage.
factors by antithrombin.
Metformin - Indicated for - inhibiting hepatic - Monitor urine
patients with gluconeogenesis and or serum
diabetes opposing the action of glucose levels
mellitus. glucagon frequently to
determine
effectiveness
of drug and
dosage.
Atorvastatin - Indicated for - Atorvastatin competitively - Use cautiously
the treatment inhibits 3-hydroxy-3 in patient with
of diabetes methylglutaryl-coenzyme A impaired renal
mellitus, (HMG-CoA) reductase function.
dyslipidemias. -
7
Clarito
DRUG STUDY
Name of Drug Special Indication Nursing Responsibility
Mechanism of Action (Relate it to
(Generic Name / (Based on patients (Based on drug’s
patient’s problem)
Brand Name) Problem) physiologic effects)
Cefepime - used to treat - inhibits bacterial cell wall - Monitor signs
bacterial synthesis by covalently of
infections binding enzymes pseudomembr
responsible for the final anous colitis,
step in transpeptidation including
during peptidoglycan wall diarrhea,
synthesis. abdominal
pain, fever,
pus or mucus
in stools, and
other severe
or prolonged
GI problems
Enoxaparin - Indicated for - acts mainly by accelerating - Assess for
the prevention the rate of the signs of
of ischemic neutralization of certain bleeding and
complications activated coagulation hemorrhage
factors by antithrombin.
Paracetamol - reduces fever - reduces fever by affecting - Do not take
the chemical messengers in other
an area of the brain that medications
containing
regulates body temperature.
acetaminophe
n without
medical
advice.
Atorvastatin - Indicated for - Atorvastatin competitively - Use cautiously
the treatment inhibits 3-hydroxy-3 in patient with
of diabetes methylglutaryl-coenzyme A impaired renal
mellitus, (HMG-CoA) reductase function.
dyslipidemias.
Chlorhexidine - Used for the - works by decreasing the - patient should
treatment of amount of bacteria in the not rinse out
gingivitis mouth, helping to reduce their mouth or
swelling and redness of the eat and drink
gums and bleeding when for 30 minutes
you brush. post using the
gel
Carvedilol - indicated for - works by slowing down - Assess for
the chronic your heart rate and making orthostatic
therapy of it easier for your heart to hypotension
heart failure, pump blood around your when assisting
hypertension, body. patient up
8
from supine
position.
Resoten/Budoten - used for the - inhibits sebaceous gland - Instruct
treatment of a function and keratinization patient to
severe form of at pharmacologic doses. report severe
acne called or unexpected
nodular acne vision
disturbances.
Aspirin - used to reduce - inhibit the synthesis of - Advise the
fever and prostaglandins, stopping the patient to
relieve mild to production of certain prevent
moderate pain natural substances that drinking
cause fever, pain, swelling, excessive
and blood clots amounts of
alcohol while
on aspirin.
Ranitidine - Maintenance - The reversible inhibition of - Decrease
of healing of H2-receptors in gastric doses in renal
duodenal or parietal cells results in a and liver
gastric ulcer. reduction in both gastric failure.
acid volume and
concentration.
Vitamin B - help prevent - act as coenzymes in a - Assess patient
Complex infections and substantial proportion of for signs of
help support or the enzymatic processes vitamin
promote that underpin every aspect deficiency
growth of red of cellular physiological before and
blood cells. functioning. periodically
during
therapy.
Salbutamol +1 cc - used to treat - promotes the production of - Monitor
PNSS asthma intracellular cyclic respiratory
adenosine monophosphate rate, oxygen
(cAMP), which enhances saturation, and
the binding of intracellular lungs sounds
calcium to the cell before and
membrane. after
administration
Amikacin - indicated in - inhibit bacteria protein - Monitor &
the short-term synthesis via binding to report any
treatment of 30S ribosome. changes in
serious I&O, oliguria,
infections due hematuria, or
to susceptible cloudy urine.
strains of
Gram-negative
bacteria
Beneprotein 4 - For use with - a phosphate binder -
scoops + individuals indicated to reduce serum
9
blenderized feeding who require phosphorus in patients with
additional end stage renal disease
protein to (ESRD).
bolster their
regular diet,
and immune
response.
N - Acetylcysteine - improves - enhances sulfate - Monitor other
oxidative conjugation of signs of
stress and unmetabolized APAP, allergic
inflammatory functions as an anti- reactions and
response in inflammatory and anaphylaxis.
patients with antioxidant, and has
community positive inotropic effects
acquired
pneumonia.
Lactulose - used as a - decreasing the intestinal - Diarrhea may
laxative in the production and absorption indicate the
treatment of of ammonia. dose is too
chronic high.
constipation in
adults and
geriatric
patients.
10
Bombio
DRUG STUDY
Name of Drug Special Indication Nursing Responsibility
Mechanism of Action (Relate it to
(Generic Name / (Based on patients (Based on drug’s
patient’s problem)
Brand Name) Problem) physiologic effects)
Atorvastatin - Indicated for - Atorvastatin competitively - Use cautiously
the treatment inhibits 3-hydroxy-3 in patient with
of diabetes methylglutaryl-coenzyme A impaired renal
mellitus, (HMG-CoA) reductase function.
dyslipidemias.
Vitamin B - help prevent - act as coenzymes in a - Assess patient
Complex infections and substantial proportion of for signs of
help support or the enzymatic processes vitamin
promote that underpin every aspect deficiency
growth of red of cellular physiological before and
blood cells. functioning. periodically
during
therapy.
Celecoxib - used to treat - a nonsteroidal anti- - Assess range
mild to inflammatory drug of motion,
moderate pain (NSAID), specifically a degree of
and help COX-2 inhibitor and works swelling, and
relieve by blocking your body's pain in
symptoms of production of certain affected joints
arthritis natural substances that before and
cause inflammation. periodically
throughout
therapy.
Folic Acid - Hemolytic - Required for nucleoprotein - Remain under
Anemia synthesis and the close medical
maintenance of normal supervision
erythropoiesis. while taking
folic acid
therapy.
Paracetamol - reduces fever - reduces fever by affecting - Do not take
the chemical messengers in other
an area of the brain that medications
regulates body temperature. containing
acetaminophe
n without
medical
advice.
11
Adis
DRUG STUDY
Name of Drug Special Indication Nursing Responsibility
Mechanism of Action (Relate it to
(Generic Name / (Based on patients (Based on drug’s
patient’s problem)
Brand Name) Problem) physiologic effects)
Lactulose - used as a - decreasing the intestinal - Diarrhea may
laxative in the production and absorption indicate the
treatment of of ammonia. dose is too
chronic high.
constipation in
adults and
geriatric
patients.
Levofloxacin - used to treat - a bactericidal antibiotic of - Monitor signs
bacterial the fluoroquinolone drug of
infections in class that directly inhibits pseudomembr
many different bacterial DNA synthesis. anous colitis,
parts of the including
body. diarrhea,
abdominal
pain, fever,
pus or mucus
in stools, and
other severe
or prolonged
GI problems
Potassium Chloride - used to - Supplemental potassium in - Administer
(KCL) prevent or to the form of high potassium oral drug after
treat low blood food or potassium chloride meals or with
levels of may be able to restore food and a full
potassium normal potassium levels. glass of water
to decrease GI
upset.
Carvedilol - indicated for - works by slowing down - Assess for
the chronic your heart rate and making orthostatic
therapy of it easier for your heart to hypotension
heart failure, pump blood around your when assisting
hypertension body. patient up
from supine
position.
Aspirin - used to reduce - inhibit the synthesis of - Advise the
fever and prostaglandins, stopping the patient to
12
relieve mild to production of certain prevent
moderate pain natural substances that drinking
cause fever, pain, swelling, excessive
and blood clots amounts of
alcohol while
on aspirin.
Spironolactone - management - acting primarily through - Give daily
of edema in competitive binding of doses early so
cirrhotic adults receptors at the that increased
not responsive aldosterone-dependent urination does
to fluid and sodium-potassium not interfere
sodium exchange site in the distal with sleep.
restrictions convoluted renal tubule.
Isosorbide Dinitrate - used to - pharmacological action of - Report any
(ISDN) prevent chest isosorbide dinitrate is rhythm
pain caused by relaxation of vascular disturbances
angina smooth muscle and or symptoms
consequent dilatation of of increased
peripheral arteries and arrhythmias.
veins
Losartan - treatment for - blocking the binding of - Monitor
hypertension angiotensin II to the AT1 symptoms of
receptor found in many high plasma
tissues.
Atorvastatin - Indicated for - Atorvastatin competitively - Use cautiously
the treatment inhibits 3-hydroxy-3 in patient with
of diabetes methylglutaryl-coenzyme A impaired renal
mellitus, (HMG-CoA) reductase function.
dyslipidemias.
Furosemide - treatment of - works by blocking the - Monitor
edema absorption of sodium, weight, intake,
chloride, and water from output, and
the filtered fluid in the serum
kidney tubules, causing a electrolyte
profound increase in the levels.
output of urine
Hydrocortisone - steroid - binds to the glucocorticoid - Monitor signs
medication receptor leading to of
that is downstream effects such as hypersensitivit
indicated to inhibition of phospholipase y reactions or
treat A2, NF-kappa B, other anaphylaxis,
inflammation inflammatory transcription including
factors, and the promotion pulmonary
13
of anti-inflammatory genes. symptoms
Butamirate Citrate - treatment of - a new class of cough - Ensure that
non- suppressants acting the drug is not
productive centrally through the taken any
(dry) cough. receptors in the brainstem longer than
recommended
to prevent
serious
adverse
effects and
severity
respiratory
tract
problems.
14
Lapiz
DRUG STUDY
Name of Drug Special Indication Nursing Responsibility
Mechanism of Action (Relate it to
(Generic Name / (Based on patients (Based on drug’s
patient’s problem)
Brand Name) Problem) physiologic effects)
Ciprofloxacin - indicated for - inhibits DNA replication by - Watch for
bacterial inhibiting bacterial DNA signs of
conjunctivitis topoisomerase and DNA- diarrhea,
gyrase. abdominal
pain, fever,
pus or mucus
in stools, or
other severe
or prolonged
GI problems
Tramadol - Indicated for - Tramadol modulates the - Monitor
moderate to descending pain pathways changes in
severe pain within the central nervous mood such as:
system through the binding confusion,
of parent and M1 malaise.
metabolite to μ- opioid
receptors and the weak
inhibition of the reuptake of
norepinephrine and
serotonin.
Ursodeoxycholic - treatment of - regulates cholesterol levels - Assess patient
Acid primary biliary by slowing the rate at carefully for
cirrhosis which the intestine is able suitability of
to absorb cholesterol and ursodiol
also acts to break down therapy
micelles, which contain
cholesterol.
Piptaz - to treat - inhibits cell wall synthesis - Watch for
bacterial by binding to bacterial cell seizures;
infections in membranes. notify
many different physician
parts of the immediately if
body patient
develops or
increases
seizure
15
activity.
Hyosine (HnBB) - treatment of - inhibiting muscarinic - use caution
abdominal acetylcholine (ACh) engaging in
pain associated receptors in the smooth- activities
with cramps muscle cells of the visceral requiring
induced by hollow organs alertness such
gastrointestina as driving or
l (GI) spasms. using
machinery.
Levetiracetam - a medicine to - modulation of synaptic - Observe for
treat epilepsy neurotransmitter release signs of
through binding to the adverse
synaptic vesicle protein effects.
SV2A in the brain.
Omeprazole - indicated for - suppresses stomach acid - Instruct
gastric ulcers secretion by specific patient to
inhibition of the H+/K+- report
ATPase system found at the bothersome or
secretory surface of gastric prolonged side
parietal cells effects
16
Flores
DRUG STUDY
Name of Drug Special Indication Mechanism of Action (Relate Nursing Responsibility (Based on
(Generic Name / Brand (Based on patients it to patient’s problem) drug’s physiologic effects)
Name) Problem)
17
ATPase system
found at the
secretory surface
of gastric parietal
cells
18
Ensoy
DRUG STUDY
Name of Drug Special Indication Nursing Responsibility
Mechanism of Action (Relate it to
(Generic Name / (Based on patients (Based on drug’s
patient’s problem)
Brand Name) Problem) physiologic effects)
Vitamin B - help prevent - act as coenzymes in a - Assess patient
Complex infections and substantial proportion of for signs of
help support or the enzymatic processes vitamin
promote that underpin every aspect deficiency
growth of red of cellular physiological before and
blood cells. functioning. periodically
during
therapy.
Omeprazole - indicated for - suppresses stomach acid - Instruct
gastric ulcers secretion by specific patient to
inhibition of the H+/K+- report
ATPase system found at the bothersome or
secretory surface of gastric prolonged side
parietal cells effects
Butamirate Citrate - treatment of - a new class of cough - Ensure that
non- suppressants acting the drug is not
productive centrally through the taken any
(dry) cough. receptors in the brainstem longer than
recommended
to prevent
serious
adverse
effects and
severity
respiratory
tract
problems.
Ceftriaxone - Treatment of - Binds to the bacterial cell - Instruct
intra- wall membrane, causing patient to
abdominal cell death. notify
infections. physician
immediately
of signs of
superinfection
, including
black, furry
19
overgrowth on
tongue,
vaginal
itching or
discharge, and
loose or foul-
smelling
stools.
KCL - used to - Supplemental potassium in - Administer
prevent or to the form of high potassium oral drug after
treat low blood food or potassium chloride meals or with
levels of may be able to restore food and a full
potassium normal potassium levels. glass of water
to decrease GI
upset.
Essential Forte - reduce - accelerated membrane - Assess
complaints of regeneration and hypersensitivit
toxic or stabilization, inhibited lipid y to drug.
dietary liver peroxidation and inhibited
damage and collagen synthesis.
hepatitis.
20
Quinquino
DRUG STUDY
Name of Drug Special Indication Nursing Responsibility
Mechanism of Action (Relate it to
(Generic Name / (Based on patients (Based on drug’s
patient’s problem)
Brand Name) Problem) physiologic effects)
Enoxaparin - Indicated for - acts mainly by accelerating - Assess for
the prevention the rate of the signs of
of ischemic neutralization of certain bleeding and
complications activated coagulation hemorrhage
factors by antithrombin.
Gabapentin - Postherpetic - Mechanism of action is not - Monitor
neuralgia known. May affect drowsiness,
transport of amino acids anxiety,
across and stabilize confusion, and
neuronal membranes. other changes
in mood or
behavior
(hostility,
emotional
lability,
concentration
difficulties).
Meropenem - Skin and skin - Binds to bacterial cell wall, - Watch for
structure resulting in cell death. seizures;
infections. notify
physician
immediately if
patient
develops or
increases
seizure
activity.
Vitamin B - help prevent - act as coenzymes in a - Assess patient
Complex infections and substantial proportion of for signs of
help support or the enzymatic processes vitamin
promote that underpin every aspect deficiency
growth of red of cellular physiological before and
blood cells. functioning. periodically
21
during
therapy.
Tramadol - Indicated for - Tramadol modulates the - Monitor
moderate to descending pain pathways changes in
severe pain within the central nervous mood such as:
system through the binding confusion,
of parent and M1 malaise.
metabolite to μ- opioid
receptors and the weak
inhibition of the reuptake of
norepinephrine and
serotonin.
Paracetamol - reduces fever - reduces fever by affecting - Do not take
the chemical messengers in other
an area of the brain that medications
regulates body temperature. containing
acetaminophe
n without
medical
advice.
22