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    Questions-Class Activity 3

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    AneesUrRahman
    The document describes the components and process of muscle contraction and relaxation. It explains how muscle contractions work through the sliding filament model and roles of the sarcoplasmic reticulum, calcium ions, troponin-tropomyosin complex, and cross-bridging of actin and myosin. It also provides questions and answers about T-tubules, how actin binding sites are made available, and effects of depleting ATP or removing T-tubules.

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    Questions-Class Activity 3

    Uploaded by

    AneesUrRahman
    14 views3 pages
    The document describes the components and process of muscle contraction and relaxation. It explains how muscle contractions work through the sliding filament model and roles of the sarcoplasmic reticulum, calcium ions, troponin-tropomyosin complex, and cross-bridging of actin and myosin. It also provides questions and answers about T-tubules, how actin binding sites are made available, and effects of depleting ATP or removing T-tubules.

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    Questions-class Activity 3

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    The document describes the components and process of muscle contraction and relaxation. It explains how muscle contractions work through the sliding filament model and roles of the sarcoplasmic reticulum, calcium ions, troponin-tropomyosin complex, and cross-bridging of actin and myosin. It also provides questions and answers about T-tubules, how actin binding sites are made available, and effects of depleting ATP or removing T-tubules.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    14 views3 pages

    Questions-Class Activity 3

    Uploaded by

    AneesUrRahman
    The document describes the components and process of muscle contraction and relaxation. It explains how muscle contractions work through the sliding filament model and roles of the sarcoplasmic reticulum, calcium ions, troponin-tropomyosin complex, and cross-bridging of actin and myosin. It also provides questions and answers about T-tubules, how actin binding sites are made available, and effects of depleting ATP or removing T-tubules.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 3

    Class Activity 3 Muscle Contraction and Relaxation Date:

    PG-2020

    Names of Students:

    Learning Objectives

    By the end of this section, you will be able to:

     Describe the components involved in a muscle contraction


     Explain how muscles contract and relax
     Describe the sliding filament model of muscle contraction

    Questions

    1.What are “T-tubules” and what is their role?

    Answer: T tubules or transverse tubules are projection of sarcolemma that runs transverse to the muscle
    fibers. They have extended nerve supply, ion channels and attachment with Sarcoplasmic Reticulum to
    transmit and spread nerve action potential efficiently .

    2. Please also describe how actin-binding sites are made available for cross-bridging with myosin heads
    during contraction.

    Answer: Ca++ ions released from Sarcoplasmic Reticulum gets attached with the troponin-tropomyosin
    complex and remove it from the actin binding site After that the actin binding site become available for
    cross-bridging with myosin heads.

    3. How would muscle contractions be affected if skeletal muscle fibers did not have T-tubules?

    Answer: T-Tubules cause the spread of action potential through out the muscle fiber if they are not
    resent action potential would not spread that efficiently

    4. What causes the striated appearance of skeletal muscle tissue?

    Answers: Alternate thick and thin filaments of actin and myosin fibers in the sarcoplasm gives the
    muscle tissues striated appearance.

    5. How would muscle contractions be affected if ATP was completely depleted in a muscle fiber?

    Answers: ATP is required for the entry of Ca++ in sarcoplasm as well as the attachment of actin and
    myosin and movement of actin filament on myosin head If the cells lack ATP the actin and myosin
    filaments do not get detached and muscles become rigid like in case of rigor mortis after death.
    Review Questions

    1.In relaxed muscle, the myosin-binding site on actin is blocked by ________.

    A. titin
    B. troponin
    C. myoglobin
    D. tropomyosin

    2. According to the sliding filament model, binding sites on actin open when ________.

    A. creatine phosphate levels rise


    B. ATP levels rise
    C. acetylcholine levels rise
    D. calcium ion levels rise

    3. The cell membrane of a muscle fiber is called ________.

    A. myofibril
    B. sarcolemma
    C. sarcoplasm
    D. myofilament

    4. Muscle relaxation occurs when ________.

    A. calcium ions are actively transported out of the sarcoplasmic reticulum


    B. calcium ions diffuse out of the sarcoplasmic reticulum
    C. calcium ions are actively transported into the sarcoplasmic reticulum
    D. calcium ions diffuse into the sarcoplasmic reticulum

    5. During muscle contraction, the cross-bridge detaches when ________.

    A. the myosin head binds to an ADP molecule


    B. the myosin head binds to an ATP molecule
    C. calcium ions bind to troponin
    D. calcium ions bind to actin

    6. Thin and thick filaments are organized into functional units called ________.

    A. myofibrils
    B. myofilaments
    C. T-tubules
    D. sarcomeres

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