OBA MSK Physio

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Course assessment Physiology

1.A long-distance athlete is having a muscle cramp after running continuously for 5 km.
Which of the following mechanisms of skeletal muscle contraction is most likely to be
affected in this athlete?
A. Bending of the myosin head with release of ADP and phosphate.
B. Binding of calcium to troponin which exposes the actin binding site.
C. Binding of the new ATP to the myosin head.
D. Formation of cross-bridge between myosin head and actin

2.Calcium needs to be released in the myofibrils in order to maintain the skeletal muscle
contraction. Which of the following structures most likely facilitates calcium release as
mentioned in the statement above?
A. Calcium pump
B. Dihydropyridine receptor
C. Ryanodine receptors
D. T-tubules

3.In an experiment, a drug is used to selectively inhibit the protein involved in smooth muscle
contraction.
Which of the following proteins is most likely to be inhibited in the above situation?
A. Calmodulin
B. Actin
C. Myosin
D. Tropomyosin

4.Which of the following muscle proteins is most important for the contraction of skeletal
muscle?
A. Myosin
B. Titin
C. Tropomyosin
D. Troponin

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