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    Exercise 4: Endocrine System Physiology: Activity 3: Hormone Replacement Therapy Lab Report

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    Alexandru Burdeniuc
    This document summarizes the results of an experiment examining the effects of different hormone therapies on rat bone density. Saline injections did not change bone density in the control rat as predicted. Estrogen injections increased bone density in the treated rat as expected. Calcitonin injections decreased bone density in the treated rat, matching the prediction. The post-lab quiz results showed the student answered only 1 of 4 questions correctly, indicating more review is needed.

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    Exercise 4: Endocrine System Physiology: Activity 3: Hormone Replacement Therapy Lab Report

    Uploaded by

    Alexandru Burdeniuc
    42 views4 pages
    This document summarizes the results of an experiment examining the effects of different hormone therapies on rat bone density. Saline injections did not change bone density in the control rat as predicted. Estrogen injections increased bone density in the treated rat as expected. Calcitonin injections decreased bone density in the treated rat, matching the prediction. The post-lab quiz results showed the student answered only 1 of 4 questions correctly, indicating more review is needed.

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    This document summarizes the results of an experiment examining the effects of different hormone therapies on rat bone density. Saline injections did not change bone density in the control rat as predicted. Estrogen injections increased bone density in the treated rat as expected. Calcitonin injections decreased bone density in the treated rat, matching the prediction. The post-lab quiz results showed the student answered only 1 of 4 questions correctly, indicating more review is needed.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    42 views4 pages

    Exercise 4: Endocrine System Physiology: Activity 3: Hormone Replacement Therapy Lab Report

    Uploaded by

    Alexandru Burdeniuc
    This document summarizes the results of an experiment examining the effects of different hormone therapies on rat bone density. Saline injections did not change bone density in the control rat as predicted. Estrogen injections increased bone density in the treated rat as expected. Calcitonin injections decreased bone density in the treated rat, matching the prediction. The post-lab quiz results showed the student answered only 1 of 4 questions correctly, indicating more review is needed.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 4

    Exercise 4: Endocrine System Physiology: Activity 3: Hormone Replacement Therapy Lab Report

    Pre-lab Quiz Results


    You have not completed the Pre-lab Quiz.

    010/10/19 page 1
    Experiment Results
    Predict Question:
    Predict Question 1: What effect will the saline injections have on the control rat's vertebral bone density?
    Your answer : c. The saline injections will not change the rat's vertebral bone density (indicated by an unchanging T score).

    Predict Question 2: What effect will the estrogen injections have on the estrogen-treated rat's vertebral bone density?
    Your answer : a. The estrogen injections will increase the rat's vertebral bone density (indicated by a less-negative T score).

    Predict Question 3: What effect will the calcitonin injections have on the calcitonin-treated rat's vertebral bone density?
    Your answer : b. The calcitonin injections will decrease the rat's vertebral bone density (indicated by a more-negative T
    score).

    Experiment Data:

    Rat Elapsed Days Saline injections Estrogen injections Calcitonin T score


    injections
    Control 7 7 0 0 -2.85
    Estrogen 7 0 7 0 -1.68
    Calcitonin 7 0 0 7 -2.33

    010/10/19 page 2
    Post-lab Quiz Results
    You scored 25% by answering 1 out of 4 questions correctly.

    1. Saline injections were used in this experiment to measure the effect of


    You correctly answered: c. a placebo on bone density.

    2. In the ovariectomized rats used in this experiment


    Your answer: b. follicle-stimulating hormone (FSH) levels were reduced because of the loss of negative feedback control.
    Correct answer: d. osteoporosis was evident prior to the injections of estrogen.

    3. Injection of calcitonin into an ovariectomized rat will


    Your answer: a. have no effect on bone density and, therefore, should be excluded from rat hormone-replacement
    therapies.
    Correct answer: b. inhibit osteoclast activity and stimulate calcium uptake and deposition in long bones.

    4. As the rat's bone density increases


    Your answer: c. the X-ray scanning assay reports a more-negative T-score.
    Correct answer: a. the X-ray scanning assay reports a less-negative T-score.

    010/10/19 page 3
    Review Sheet Results
    1. Why were ovariectomized rats used in this experiment? How does the fact that the rats are ovariectomized explain their
    baseline T scores?
    You did not answer this question.

    2. What effect did the administration of saline injections have on the control rat? How well did the results compare with
    your prediction?
    You did not answer this question.

    3. What effect did the administration of estrogen injections have on the estrogen-treated rat? How well did the results
    compare with your prediction?
    You did not answer this question.

    4. What effect did the administration of calcitonin injections have on the calcitonin-treated rat? How well did the results
    compare with your prediction?
    You did not answer this question.

    5. What are some health risks that postmenopausal women must consider when contemplating estrogen
    hormone-replacement therapy?
    You did not answer this question.

    010/10/19 page 4

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