Ketorolac and Nalbuphine

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NAME CLASSIFICATION MECHANISM OF INDICATIONS & SIDE EFFECTS NURSING

ACTION CONTRAINDICATIO RESPONSIBILITIES


NS
Generic Name: Analgesic; Synthetic narcotic INDICATIONS Common - Assess respiratory
Nalbuphine CNS agent; analgesic with -sedation rate before drug
Hydrochloride Narcotic Opiate agonist and weak - indicated for the -sweaty/clammy administration.
Agonist-antagogist antagonist properties. relief of moderate to -nausea/vomiting Withhold drug and
Brand Name: Analgesic potency is severe pain. -dizziness/vertigo notify physician if
Nubain about 3 to 4 times -dry mouth respiratory rate falls
greater than that of - Nalbuphine -headache below 12.
Dosage: pentazocine and hydrochloride can - Watch for allergic
IV 5mg q 4 hours for approximately equal also be used as a reaction in persons
6 doses to that produced by supplement to with sulfite
equivalent doses of balanced anesthesia, sensitivity
morphine. for preoperative and - Administer with
Nalbuphine postoperative caution to patients
hydrochloride may analgesia, and for with hepatic and
produce the same obstetrical analgesia renal impairment
degree of respiratory during labor and - Monitor ambulatory
depression as delivery. patients, nalbuphine
equianalgesic doses can cause
of morphine. drowsiness
However, nalbuphine CONTRAINDICATIO - Avoid abrupt
hydrochloride NS termination of
exhibits a ceiling nalbuphine
effect such that - known following prolonged
increases in dose hypersensitivity to use which may
greater than 30 mg nalbuphine produce similar
do not produce hydrochloride, or to symptoms similar to
further respiratory any of the other narcotic withdrawal
depression in the ingredients in such as nausea,
absence of other CNS nalbuphine vomiting, abdominal
active medications hydrochloride cramps, lacrimation,
affecting respiration. injection. nasal congestion,
- History of emotional fever, restlessness
instability or drug and anxiety
abuse - Advise patient not
- increased ICP to engage in
- Impaired potentially
respirations hazardous activities
- impaired liver and until response to
kidney functions drug is known
- MI - Avoid alcohol and
- Biliary tract other CNS
infection
depressant
NAME CLASSIFICATION MECHANISM OF INDICATIONS & SIDE EFFECTS NURSING
ACTION CONTRAINDICATIO RESPONSIBILITIES
NS
Generic Name: • CNS agent • It inhibit synthesis • Light- • Watch for
Ketorolac • NSAID of prostaglandins INDICATIONS headedness signs and
• Analgesic and is a peripherally • Dizziness symptoms of GI
Brand Name: • Antipyretic acting analgesic. • Short term • drowsiness ulceration and
Toradol Ketorolac does not management of • GI ulceration bleeding (eg.
have any known PAIN • bleeding and Hematomesis,
Dosage: effects on opiate • Ocular itvhing due black tarry stool)
perforation
IV 15mg q 6 hours for receptors to seasonal • postoperative
6 doses allergic bleeding • Note for
conjunctivitis • acute renal possible adverse
failure effects such as
• anaphylactic light-headedness,
CONTRAINDICATIO and anaphylactoid dizziness,
NS reactions drowsiness
• liver failure • advise patient
• Hypersensitivity to not to engage with
ketorolac hazardous
activities or
• patients with the driving
complete or partial
• do not give
syndrome of nasal
NSAIDs while
polyps
taking this drug
• angioedema, • Monitor for I
• bronchospastic and O.
reactivity • Advised
• other allergic patient to increase
manifestations to OFI if not
aspirin or other contraindicated
non-steroidal anti-
inflammatory
• Monitor for
drugs (due to
fluid retention or
possibility of
edema specially
severe
with patient with
anaphylaxis).
Hx of CHF
• should be avoided
in patients with
renal (kidney)
dysfunction.
• Patients with
compromised renal
function (e.g.,
heart failure,
diuretic use,
cirrhosis,
dehydration, and
renal
insufficiency).

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