Calcium/Sodium Hypochlorite

Calcium Hypochlorite (CaCl2O2)/Sodium Hypochlorite (NaOCl)

CAS 7778-54-3/7681-52-9; UN 1748/1791

Synonyms of calcium hypochlorite include Losantin, hypochlorous acid, calcium salt, BK powder, Hy-Chlor,
chlorinated lime, lime chloride, chloride of lime, calcium oxychloride, HTH, mildew remover X-14,
perchloron, and pittchlor.

Synonyms of sodium hypochlorite include Clorox, bleach, liquid bleach, sodium oxychloride, Javex,
antiformin, showchlon, chlorox, B-K, Carrel-dakin solution, Chloros, Dakins solution, hychlorite, Javelle
water, Mera Industries 2MOM3B, Milton, modified dakins solution, Piochlor, and 13% active chlorine.

Persons contaminated with calcium hypochlorite dust, or whose clothing or skin is

soaked with industrial-strength hypochlorite solutions may be corrosive to rescuers
and may release harmful vapor. Individuals exposed only to gases released by
hypochlorite pose little risk of secondary contamination to others.

Calcium hypochlorite is generally available as a white powder, pellets, or flat plates;

sodium hypochlorite is usually a greenish yellow, aqueous solution. Although not
flammable, they may react explosively. Calcium hypochlorite decomposes in water
to release chlorine and oxygen; sodium hypochlorite solutions can react with acids
or ammonia to release chlorine or chloramine. Odor may not provide an adequate
warning of hazardous concentrations.

Both hypochlorites are toxic by the oral and dermal routes and can react to release
chlorine or chloramine which can be inhaled. The toxic effects of sodium and calcium
hypochlorite are primarily due to the corrosive properties of the hypochlorite
moiety. Systemic toxicity is rare, but metabolic acidosis may occur after ingestion.

Description Calcium hypochlorite is generally available as a white powder,

pellets, or flat plates. It decomposes readily in water or when
heated, releasing oxygen and chlorine. It has a strong chlorine odor,
but odor may not provide an adequate warning of hazardous
concentrations . Calcium hypochlorite is not flammable, but it acts
as an oxidizer with combustible material and may react explosively
with ammonia, amines, or organic sulfides. Calcium hypochlorite
should be stored in a dry, well ventilated area at a temperature
below 120 F (50 C) separated from acids, ammonia, amines, and
other chlorinating or oxidizing agents.

Sodium hypochlorite is generally sold in aqueous solutions containing

5 to 15% sodium hypochlorite, with 0.25 to 0.35% free alkali
(usually NaOH) and 0.5 to 1.5% NaCl. Solutions of up to 40%

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Calcium/Sodium Hypochlorite

sodium hypochlorite are available, but solid sodium hypochlorite is

not commercially used. Sodium hypochlorite solutions are a clear,
greenish yellow liquid with an odor of chlorine. Odor may not
provide an adequate warning of hazardous concentrations .
Sodium hypochlorite solutions can liberate dangerous amounts of
chlorine or chloramine if mixed with acids or ammonia. Anhydrous
sodium hypochlorite is very explosive. Hypochlorite solutions should
be stored at a temperature not exceeding 20 C away from acids in
well-fitted air-tight bottles away from sunlight.

Routes of Exposure

Inhalation Hypochlorite solutions can liberate toxic gases such as chlorine.

Chlorines odor or irritant properties generally provide adequate
warning of hazardous concentrations. However, prolonged, low-
level exposures, such as those that occur in the workplace, can lead
to olfactory fatigue and tolerance of chlorines irritant effects.
Chlorine is heavier than air and may cause asphyxiation in poorly
ventilated, enclosed, or low-lying areas.

Children exposed to the same levels of gases as adults may receive

a larger dose because they have greater lung surface area:body
weight ratios and higher minute volumes:weight ratios. Children may
be more vulnerable to corrosive agents than adults because of the
smaller diameter of their airways. In addition, they may be exposed
to higher levels than adults in the same location because of their short
stature and the higher levels of chlorine found nearer to the ground.

Skin/Eye Contact Direct contact with hypochlorite solutions, powder, or concentrated

vapor causes severe chemical burns, leading to cell death and
ulceration.

Because of their relatively larger surface area:weight ratio, children

are more vulnerable to toxicants affecting the skin.

Ingestion Ingestion of hypochlorite solutions causes vomiting and corrosive

injury to the gastrointestinal tract. Household bleaches (3 to 6%
sodium hypochlorite) usually cause esophageal irritation, but rarely
cause strictures or serious injury such as perforation. Commercial
bleaches may contain higher concentrations of sodium hypochlorite
and are more likely to cause serious injury. Metabolic acidosis is
rare, but has been reported following the ingestion of household
bleach. Pulmonary complications resulting from aspiration may also
be seen after ingestion.

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 Calcium/Sodium Hypochlorite

Sources/Uses Sodium and calcium hypochlorite are manufactured by the

chlorination of sodium hydroxide or lime. Sodium and calcium
hypochlorite are used primarily as oxidizing and bleaching agents or
disinfectants. They are components of commercialbleaches, cleaning
solutions, and disinfectants for drinking water and waste water
purification systems and swimming pools (Teitelbaum 2001).

Standards and
Guidelines AIHA WEEL:
STEL (15-min) = 2 mg/m3

Physical Properties Calcium Hypochlorite Sodium Hypochlorite

Description: White powder, pellets or Clear greenish yellow liquid

flat plates
Warning properties: Chlorine odor; inadequate Chlorine odor; inadequate
warning of hazardous warning of hazardous
concentrations concentrations

Molecular weight: 142.98 daltons 74.44 daltons

Boiling point (760 mm Hg): Decomposes at 100 C Decomposes above 40 C
(HSDB 2001) (HSDB 2001)

Freezing point: Not applicable 6 C (21 F)

Specific gravity: 2.35 (water = 1) 1.21 (14% NAOCl solution)
(water = 1 )

Water solubility: 21.4% at 76 F (25 C) 29.3 g/100 g at 32 F (0 C)

Flammability: Not flammable Not flammable

Incompatibilities Calcium or sodium hypochlorite react explosively or form explosive

compounds with many common substances such as ammonia,
amines, charcoal, or organic sulfides.

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Health Effects

Hypochlorite powder, solutions, and vapor are irritating and corrosive to the eyes,
skin, and respiratory tract. Ingestion and skin contact produces injury to any
exposed tissues. Exposure to gases released from hypochlorite may cause burning
of the eyes, nose, and throat; cough as well as constriction and edema of the airway
and lungs can occur.

Hypochlorite produces tissue injury by liquefaction necrosis. Systemic toxicity is

rare, but metabolic acidosis may occur after ingestion.

Acute Exposure The toxic effects of sodium and calcium hypochlorite are primarily
due to the corrosive properties of the hypochlorite moiety.
Hypochlorite causes tissue damage by liquefaction necrosis. Fats
and proteins are saponified, resulting in deep tissue destruction.
Further injury is caused by thrombosis of blood vessels. Injury
increases with hypochlorite concentration and pH. Symptoms may
be apparent immediately or delayed for a few hours. Calcium
hypochlorite decomposes in water releasing chlorine gas. Sodium
hypochlorite solutions liberate the toxic gases chlorine or chloramine
if mixed with acid or ammonia (this can occur when bleach is mixed
with another cleaning product). Thus, exposure to hypochlorite may
involve exposure to these gases.

Children do not always respond to chemicals in the same way that

adults do. Different protocols for managing their care may be
needed.

Gastrointestinal Pharyngeal pain is the most common symptom after ingestion of

hypochlorite, but in some cases (particularly in children), significant
esophagogastric injury may not have oral involvement. Additional
symptoms include dysphagia, stridor, drooling, odynophagia, and
vomiting. Pain in the chest or abdomen generally indicates more
severe tissue damage. Respiratory distress and shock may be
present if severe tissue damage has already occurred. In children,
refusal to take food or drink liquid may represent odynophagia.

Ingestion of hypochlorite solutions or powder can also cause severe

corrosive injury to the mouth, throat, esophagus, and stomach, with
bleeding, perforation, scarring, or stricture formation as potential
sequelae.

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Calcium/Sodium Hypochlorite

Dermal Hypochlorite irritates the skin and can cause burning pain,
inflammation, and blisters. Damage may be more severe than is
apparent on initial observation and can continue to develop over
time.

Because of their relatively larger surface area:body weight ratio,

children are more vulnerable to toxins affecting the skin.

Ocular Contact with low concentrations of household bleach causes mild

and transitory irritation if the eyes are rinsed, but effects are more
severe and recovery is delayed if the eyes are not rinsed. Exposure
to solid hypochlorite or concentrated solutions can produce severe
eye injuries with necrosis and chemosis of the cornea, clouding of
the cornea, iritis, cataract formation, or severe retinitis.

Respiratory Ingestion of hypochlorite solutions may lead to pulmonary

complications when the liquid is aspirated. Inhalation of gases
released from hypochlorite solutions may cause eye and nasal
irritation, sore throat, and coughing at low concentrations. Inhalation
of higher concentrations can lead to respiratory distress with airway
constriction and accumulation of fluid in the lungs (pulmonary
edema). Patients may exhibit immediate onset of rapid breathing,
cyanosis, wheezing, rales, or hemoptysis. Pulmonary injury may
occur after a latent period of 5 minutes to 15 hours and can lead to
reactive airways dysfunction syndrome (RADS), a chemical irritant-
induced type of asthma.

Children may be more vulnerable to corrosive agents than adults

because of the smaller diameter of their airways. Children may also
be more vulnerable to gas exposure because of increased minute
ventilation per kg and failure to evacuate an area promptly when
exposed.

Metabolic Metabolic acidosis has been reported in some cases after ingestion
of household bleach.

Potential Sequelae Exposure to toxic gases generated from hypochlorite solutions can
lead to reactive airways dysfunction syndrome (RADS), a chemical
irritant-induced type of asthma. Chronic complications following
ingestion of hypochlorite include esophageal obstruction, pyloric
stenosis, squamous cell carcinoma of the esophagus, and vocal cord
paralysis with consequent airway obstruction.

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Chronic Exposure Chronic dermal exposure to hypochlorite can cause dermal irritation.

Carcinogenicity The International Agency for Research on Cancer has determined

that hypochlorite salts are not classifiable as to their carcinogenicity
to humans.

Reproductive and
Developmental Effects No information was located regarding reproductive or
developmental effects of calcium or sodium hypochlorite in
experimental animals or humans. Calcium and sodium hypochlorite
are not included in Reproductive and Developmental Toxicants,
a 1991 report published by the U.S. General Accounting Office
(GAO) that lists 30 chemicals of concern because of widely
acknowledged reproductive and developmental consequences.

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Prehospital Management

Rescue personnel are at low risk of secondary contamination from victims who have
been exposed only to gases released from hypochlorite solutions. However, clothing
or skin soaked with industrial-strength bleach or similar solutions may be corrosive
to rescuers and may release harmful gases.

Ingestion of hypochlorite solutions may cause pain in the mouth or throat,

dysphagia, stridor, drooling, odynophagia, and vomiting. Hypochlorite irritates the
skin and can cause burning pain, inflammation, and blisters. Acute exposure to
gases released from hypochlorite solutions can cause coughing, eye and nose
irritation, lacrimation, and a burning sensation in the chest. Airway constriction and
noncardiogenic pulmonary edema may also occur.

There is no specific antidote for hypochlorite poisoning. Treatment is supportive.

Hot Zone Rescuers should be trained and appropriately attired before entering
the Hot Zone. If the proper equipment is not available, or if rescuers
have not been trained in its use, assistance should be obtained from
a local or regional HAZMAT team or other properly equipped
response organization.

Rescuer Protection Hypochlorite is irritating to the skin and eyes and in some cases may
release toxic gases.

Respiratory Protection: Positive-pressure, self-contained breathing

apparatus (SCBA) is recommended in response to situations that
involve exposure to potentially unsafe levels of chlorine gas.

Skin Protection: Chemical-protective clothing should be worn due

to the risk of skin irritation and burns from direct contact with solid
hypochlorite or concentrated solutions.

ABC Reminders Quickly establish a patent airway, ensure adequate respiration and
pulse. If trauma is suspected, maintain cervical immobilization
manually and apply a cervical collar and a backboard when feasible.

Victim Removal If victims can walk, lead them out of the Hot Zone to the
Decontamination Zone. Victims who are unable to walk may be
removed on backboards or gurneys; if these are not available,
carefully carry or drag victims to safety.

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Calcium/Sodium Hypochlorite

Consider appropriate management in victims with chemically-

induced acute disorders, especially children who may suffer
separation anxiety if separated from a parent or other adult.

Decontamination Zone Victims exposed only to chlorine gas released by hypochlorite who
have no skin or eye irritation do not need decontamination. They
may be transferred immediately to the Support Zone. All others
require decontamination as described below.

Rescuer Protection If exposure levels are determined to be safe, decontamination may

be conducted by personnel wearing a lower level of protection than
that worn in the Hot Zone (described above).

ABC Reminders Quickly establish a patent airway, ensure adequate respiration and
pulse. Stabilize the cervical spine with a collar and a backboard if
trauma is suspected. Administer supplemental oxygen as required.
Assist ventilation with a bag-valve-mask device if necessary.

Basic Decontamination Rapid decontamination is critical. Victims who are able may
assist with their own decontamination. Remove and double-bag
contaminated clothing and personal belongings.

Flush exposed skin and hair with copious amounts of plain tepid
water. Use caution to avoid hypothermia when decontaminating
victims, particularly children or the elderly. Use blankets or warmers
after decontamination as needed.

Irrigate exposed or irritated eyes with saline, Ringers lactate, or

D5W for at least 20 minutes. Eye irrigation may be carried out
simultaneously with other basic care and transport. Remove contact
lenses if it can be done without additional trauma to the eye. If a
corrosive material is suspected or if pain or injury is evident,
continue irrigation while transferring the victim to the support zone.

In cases of ingestion, do not induce emesis or offer activated

charcoal.

Victims who are conscious and able to swallow should be given 4

to 8 ounces of water or milk; if the victim is symptomatic, delay
decontamination until other emergency measures have been
instituted. Dilutants are contraindicated in the presence of shock,
upper airway obstruction, or in the presence of perforation.

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 Calcium/Sodium Hypochlorite

Consider appropriate management of chemically contaminated

children at the exposure site. Provide reassurance to the child during
decontamination, especially if separation from a parent occurs.

Transfer to Support Zone As soon as basic decontamination is complete, move the victim to
the Support Zone.

Support Zone Be certain that victims have been decontaminated properly (see
Decontamination Zone above). Victims who have undergone
decontamination or have been exposed only to vapor pose no
serious risks of secondary contamination to rescuers. In such cases,
Support Zone personnel require no specialized protective gear.

ABC Reminders Quickly establish a patent airway, ensure adequate respiration and
pulse. If trauma is suspected, maintain cervical immobilization
manually and apply a cervical collar and a backboard when feasible.
Administer supplemental oxygen as required and establish
intravenous access if necessary. Place on a cardiac monitor, if
available.

Additional Decontamination Continue irrigating exposed skin and eyes, as appropriate.

In cases of ingestion, do not induce emesis or offer activated

charcoal.

Victims who are conscious and able to swallow should be given 4

to 8 ounces of water or milk; if the victim is symptomatic, delay
decontamination until other emergency measures have been
instituted. Dilutants are contraindicated in the presence of shock,
upper airway obstruction, or in the presence of perforation.

Advanced Treatment In cases of respiratory compromise secure airway and respiration

via endotracheal intubation. Avoid blind nasotracheal intubation or
use of an esophageal obturator: only use direct visualization to
intubate. When the patients condition precludes endotracheal
intubation, perform cricothyrotomy if equipped and trained to do so.

Treat patients who have bronchospasm with an aerosolized

bronchodilator such as albuterol.

Consider racemic epinephrine aerosol for children who develop

stridor. Dose 0.250.75 mL of 2.25% racemic epinephrine solution
in water, repeat every 20 minutes as needed cautioning for
myocardial variability.

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Calcium/Sodium Hypochlorite

Patients who are comatose, hypotensive, or having seizures or who

have cardiac arrhythmias should be treated according to advanced
life support (ALS) protocols.

Transport to Medical Facility Only decontaminated patients or those not requiring decontamination
should be transported to a medical facility. Body bags are not
recommended.

Report to the base station and the receiving medical facility the
condition of the patient, treatment given, and estimated time of
arrival at the medical facility.

If a chemical has been ingested, prepare the ambulance in case the

victim vomits toxic material. Have ready several towels and open
plastic bags to quickly clean up and isolate vomitus.

Multi-Casualty Triage Consult with the base station physician or the regional poison control
center for advice regarding triage of multiple victims.

Patients who have ingested hypochlorite, or who show evidence of

significant exposure to hypochlorite or chlorine (e.g., severe or
persistent cough, dyspnea or chemical burns) should be transported
to a medical facility for evaluation. Patients who have minor or
transient irritation of the eyes or throat may be discharged from the
scene after their names, addresses, and telephone numbers are
recorded. They should be advised to seek medical care promptly if
symptoms develop or recur (see Patient Information Sheet
below).

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 Calcium/Sodium Hypochlorite

Emergency Department Management

Hospital personnel are at low risk of secondary contamination from victims who have
been exposed only to gases released from hypochlorite solutions. However, clothing
or skin soaked with industrial-strength bleach or similar solutions may be corrosive to
rescuers and may release harmful gases.

Ingestion of hypochlorite solutions may cause pain in the mouth or throat, dysphagia,
stridor, drooling, odynophagia, and vomiting. Hypochlorite irritates the skin and can
cause burning pain, inflammation, and blisters. Acute exposure to gases released
from hypochlorite solutions can cause coughing, eye and nose irritation, lacrimation,
and a burning sensation in the chest. Airway constriction and noncardiogenic
pulmonary edema may also occur.

There is no specific antidote for hypochlorite poisoning. Treatment requires

supportive care.

Decontamination Area Unless previously decontaminated, all patients suspected of contact

with hypochlorite and all victims with skin or eye irritation require
decontamination as described below. Patients exposed only to
chlorine gas who have no skin or eye irritation may be transferred
immediately to the Critical Care Area. Because hypochlorite is an
irritant, don butyl rubber gloves and apron before treating patients.

Be aware that use of protective equipment by the provider may

cause anxiety, particularly in children, resulting in decreased
compliance with further management efforts.

Because of their relatively larger surface area:weight ratio, children

are more vulnerable to toxicants affecting the skin. Also, emergency
department personnel should examine childrens mouths because of
the frequency of hand-to-mouth activity among children.

ABC Reminders Evaluate and support airway, breathing, and circulation. Children
may be more vulnerable to corrosive agents than adults because of
the smaller diameter of their airways. In cases of respiratory
compromise secure airway and respiration via endotracheal
intubation. If not possible, surgically secure an airway.

Treat patients who have bronchospasm with an aerosolized

bronchodilator such as albuterol.

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Calcium/Sodium Hypochlorite

Consider racemic epinephrine aerosol for children who develop

stridor. Dose 0.250.75 mL of 2.25% racemic epinephrine solution
in water, repeat every 20 minutes as needed cautioning for
myocardial variability.

Patients who are comatose, hypotensive, or having seizures or

cardiac arrhythmias should be treated in the conventional manner.

Metabolic acidosis can be managed with intravenous sodium

bicarbonate and buffer solutions.

Basic Decontamination Patients who are able may assist with their own decontamination.
Remove and double bag contaminated clothing and personal
belongings.

Flush exposed skin and hair with copious amounts of plain water.
Use caution to avoid hypothermia when decontaminating victims,
particularly children or the elderly. Use blankets or warmers after
decontamination as needed.

Irrigate exposed or irritated eyes with saline, Ringers lactate, or

D5W for at least 20 minutes. Remove contact lenses if it can be
done without additional trauma to the eye. Continue irrigation while
transporting the patient to the Critical Care Area.

In cases of ingestion, do not induce emesis or offer activated

charcoal.

Victims who are conscious and able to swallow should be given 4

to 8 ounces of water or milk. Dilutants are contraindicated in the
presence of shock, upper airway obstruction, or in the presence of
perforation.

Critical Care Area Be certain that appropriate decontamination has been carried out
(see Decontamination Area above).

ABC Reminders Evaluate and support airway, breathing, and circulation as in ABC
Reminders above. Children may be more vulnerable to corrosive
agents than adults because of the smaller diameter of their airways.
Establish intravenous access in seriously ill patients if this has not
been done previously. Continuously monitor cardiac rhythm.

Patients who are comatose, hypotensive, or having seizures or

cardiac arrhythmias should be treated in the conventional manner.

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 Calcium/Sodium Hypochlorite

Metabolic acidosis can be managed with intravenous sodium

bicarbonate and buffer solutions.

Inhalation Exposure Administer supplemental oxygen by mask to patients who have

respiratory symptoms. Treat patients who have bronchospasm with
an aerosolized bronchodilator such as albuterol.

Consider racemic epinephrine aerosol for children who develop

stridor. Dose 0.250.75 mL of 2.25% racemic epinephrine solution
in water, repeat every 20 minutes as needed cautioning for
myocardial variability.

Skin Exposure If concentrated hypochlorite solutions contact the skin, chemical

burns may occur; treat as thermalburns. Patients developing dermal
hypersensitivity reactions may require treatment with systemic or
topical corticosteroids or antihistamines.

Because of their relatively larger surface area:body weight ratio

children are more vulnerable to toxicants that affect the skin.

Eye Exposure Irrigate exposed or irritated eyes with saline, Ringers lactate, or
D5W for at least 20 minutes. Check the pH of the conjunctiva every
30 minutes for 2 hours after irrigation is stopped. If the pH is not
neutral an irrigating contact lens should be used to apply continuous
irrigation for several hours until the pH of the tissue normalizes. Test
visual acuity and examine the eyes for corneal damage and treat
appropriately. Immediately consult an ophthalmologist for patients
who have corneal injuries.

Ingestion In cases of ingestion, do not induce emesis or offer activated

charcoal.

Give 4 to 8 ounces of water or milk to alert patients who can

swallow if not done previously. Dilutants are contraindicated in the
presence of shock, upper airway obstruction, or in the presence of
perforation.

Direct visualization of the esophagus is of primary importance for

determining the extent of injury. All patients who are suspected of
having significant ingestion, or those (such as children) for whom
there is an unreliable history, must have early endoscopy within 36
to 48 hours of ingestion. Use of a flexible endoscope is associated
with a lower risk of perforation. The esophagus, stomach and
duodenum should be endoscopically evaluated because burns of the

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Calcium/Sodium Hypochlorite

esophagus do not correlate with the presence of burns in the

stomach.

Contraindications for endoscopy include: unstable patient, evidence

of perforation, upper airway compromise, or more than 48 hours
after ingestion.

Gastric lavage is not generally recommended for hypochlorite

ingestion.

Antidotes and
Other Treatments There is no specific antidote for hypochlorite. Treatment is
supportive.

Laboratory Tests The diagnosis of acute hypochlorite toxicity is primarily clinical.

However, laboratory testing is useful for monitoring the patient and
evaluating complications. Routine laboratory studies for all exposed
patients include CBC, glucose, and electrolyte determinations.
Patients who have respiratory complaints may require pulse oximetry
(or ABG measurements) and chest radiography. Chlorine inhalation
may be complicated by hyperchloremic metabolic acidosis; in
addition to electrolytes, monitor blood pH.
Disposition and
Follow-up Consider hospitalizing patients who have a suspected significant
exposure or have eye burns or serious skin burns. Patients with
perforation should be prepared for emergency surgery.

Delayed Effects Patients who ingested large volumes of hypochlorite, who have
unreliable histories, or are symptomatic complaining of pain in
swallowing, persistent shortness of breath, severe cough, or chest
tightness should be admitted to the hospital and observed until
symptom-free. Injury may progress for several hours.

Patient Release Asymptomatic patients and those who experienced only minor
irritation of the nose, throat, eyes, or respiratory tract may be
released. In most cases, these patients will be free of symptoms in
an hour or less. They should be advised to seek medical care
promptly if symptoms develop or recur (see the
HypochloritePatient Information Sheet below).

Follow-up Obtain the name of the patients primary care physician so that the
hospital can send a copy of the ED visit to the patients doctor.

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 Calcium/Sodium Hypochlorite

Follow up is recommended for all hospitalized patients because

long-term gastrointestinal or respiratory problems can result.
Respiratory monitoring is recommended until the patient is symptom-
free. Chlorine-induced reactive airways dysfunction syndrome
(RADS) has been reported to persist from 2 to 12 years.

Patients who have skin or corneal injury should be re-examined

within 24 hours.

Reporting If a work-related incident has occurred, you may be legally required

to file a report; contact your state or local health department.

Other persons may still be at risk in the setting where this incident
occurred. If the incident occurred in the workplace, discussing it
with company personnel may prevent future incidents. If a public
health risk exists, notify your state or local health department or
other responsible public agency. When appropriate, inform patients
that they may request an evaluation of their workplace from OSHA
or NIOSH. See Appendix III for a list of agencies that may be of
assistance.

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Calcium/Sodium Hypochlorite

18 Emergency Department Management ATSDR

 Calcium/Sodium Hypochlorite

Calcium/Sodium Hypochlorite
Patient Information Sheet

This handout provides information and follow-up instructions for persons who have been exposed to calcium
or sodium hypochlorite.

What is hypochlorite?
Calcium hypochlorite is generally available as a white powder, pellets, or flat plates, while sodium hypochlorite
is usually a greenish yellow, aqueous solution. Hypochlorite is used widely in cleaning agents, and in bleaching,
drinking-water and swimming-pooldisinfecting. Calcium hypochlorite decomposes in water to release chlorine
and sodium hypochlorite solutions and can release chlorine gas if mixed with other cleaning agents.

What immediate health effects can be caused by exposure to hypochlorite?

Hypochlorite powder, solutions, and vapor are irritating and corrosive. Swallowing hypochlorite or contact
with the skin or eyes produces injury to any exposed tissues. Exposure to gases released from hypochlorite
may cause burning of the eyes, nose, and throat; cough; and damage to the airway and lungs. Generally, the
more serious the exposure, the more severe the symptoms.

Can hypochlorite poisoning be treated?

There is no antidote for hypochlorite, but its effects can be treated and most exposed persons get well.
Persons who have experienced serious symptoms may need to be hospitalized.

Are any future health effects likely to occur?

A single small exposure from which a person recovers quickly is not likely to cause delayed or long-term
effects. After a serious exposure, symptoms may worsen for several hours.

What tests can be done if a person has been exposed to hypochlorite?

Specific tests for the presence of hypochlorite in blood or urine generally are not useful to the doctor. If a
severe exposure has occurred, blood and urine analyses and other tests may show whether the lungs, heart,
or brain have been injured. Testing is not needed in every case.

Where can more information about hypochlorite be found?

More information about hypochlorite can be obtained from your regional poison control center, your state,
county, or local health department; the Agency for Toxic Substances and Disease Registry (ATSDR); your
doctor; or a clinic in your area that specializes in occupational and environmental health. If the exposure
happened at work, you may wish to discuss it with your employer, the Occupational Safety and Health
Administration (OSHA), or the National Institute for Occupational Safety and Health (NIOSH). Ask the
person who gave you this form for help in locating these telephone numbers.

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Calcium/Sodium Hypochlorite

Follow-up Instructions

Keep this page and take it with you to your next appointment. Follow only the instructions checked below.

[ ] Call your doctor or the Emergency Department if you develop any unusual signs or symptoms within the
next 24 hours, especially:

difficulty swallowing, or pain in the abdomen or chest

coughing or wheezing, difficulty breathing, shortness of breath, or chest pain
increased ocular pain or discharge, change in vision
increased redness or pain or a pus-like discharge in the area of a skin burn

[ ] No follow-up appointment is necessary unless you develop any of the symptoms listed above.
[ ] Call for an appointment with Dr. in the practice of .
When you call for your appointment, please say that you were treated in the Emergency Department at
Hospital by and were advised
to be seen again in days.
[ ] Return to the Emergency Department/ Clinic on (date)
at AM/PM for a follow-up examination.
[ ] Do not perform vigorous physical activities for 1 to 2 days.
[ ] You may resume everyday activities including driving and operating machinery.
[ ] Do not return to work for days.
[ ] You may return to work on a limited basis. See instructions below.
[ ] Avoid exposure to cigarette smoke for 72 hours; smoke may worsen the condition of your lungs.
[ ] Avoid drinking alcoholic beverages for at least 24 hours; alcohol may worsen injury to your
stomach or have other effects.
[ ] Avoid taking the following medications:
[ ] You may continue taking the following medication(s) that your doctor(s) prescribed for you:

[ ] Other instructions:

Provide the Emergency Department with the name and the number of your primary care physician so that
the ED can send him or her a record of your emergency department visit.

You or your physician can get more information on the chemical by contacting:
or , or by checking out the following Internet
Web sites: ; .

Signature of patient Date

Signature of physician Date

20 Patient Information Sheet ATSDR