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    Pfizer Neusentis Molecular/Cellular Biology Industrial Trainee (2 Positions)

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    The document describes two industrial trainee positions at Pfizer's Neusentis research unit focused on new science therapeutics. The trainees will work on projects involving stem cell technologies, ion channels, neurotrophins, and solute carriers to further understanding of pain and sensory disorders and to develop new treatments. Examples of potential projects include studying stem cell differentiation, screening targets involved in disease mechanisms, analyzing solute carrier trafficking modulated by small molecules, and characterizing nociceptor subpopulations. The ideal candidates will have lab skills in areas like molecular biology, biochemistry, and pharmacology, and attributes such as enthusiasm, creativity, and strong communication and teamwork abilities.

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    Pfizer Neusentis Molecular/Cellular Biology Industrial Trainee (2 Positions)

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    api-237308802
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    The document describes two industrial trainee positions at Pfizer's Neusentis research unit focused on new science therapeutics. The trainees will work on projects involving stem cell technologies, ion channels, neurotrophins, and solute carriers to further understanding of pain and sensory disorders and to develop new treatments. Examples of potential projects include studying stem cell differentiation, screening targets involved in disease mechanisms, analyzing solute carrier trafficking modulated by small molecules, and characterizing nociceptor subpopulations. The ideal candidates will have lab skills in areas like molecular biology, biochemistry, and pharmacology, and attributes such as enthusiasm, creativity, and strong communication and teamwork abilities.

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    The document describes two industrial trainee positions at Pfizer's Neusentis research unit focused on new science therapeutics. The trainees will work on projects involving stem cell technologies, ion channels, neurotrophins, and solute carriers to further understanding of pain and sensory disorders and to develop new treatments. Examples of potential projects include studying stem cell differentiation, screening targets involved in disease mechanisms, analyzing solute carrier trafficking modulated by small molecules, and characterizing nociceptor subpopulations. The ideal candidates will have lab skills in areas like molecular biology, biochemistry, and pharmacology, and attributes such as enthusiasm, creativity, and strong communication and teamwork abilities.

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    © All Rights Reserved
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    25 views2 pages

    Pfizer Neusentis Molecular/Cellular Biology Industrial Trainee (2 Positions)

    Uploaded by

    api-237308802
    The document describes two industrial trainee positions at Pfizer's Neusentis research unit focused on new science therapeutics. The trainees will work on projects involving stem cell technologies, ion channels, neurotrophins, and solute carriers to further understanding of pain and sensory disorders and to develop new treatments. Examples of potential projects include studying stem cell differentiation, screening targets involved in disease mechanisms, analyzing solute carrier trafficking modulated by small molecules, and characterizing nociceptor subpopulations. The ideal candidates will have lab skills in areas like molecular biology, biochemistry, and pharmacology, and attributes such as enthusiasm, creativity, and strong communication and teamwork abilities.

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    © All Rights Reserved
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    of 2

    Pfizer UK Industrial Trainee Scheme 2015/2016

    Pfizer Neusentis
    Molecular/Cellular Biology Industrial Trainee (2 positions)


    DEPARTMENT OVERVIEW

    Neusentis is a Pfizer Research Unit focussed on New Science Therapeuticsand was launched in 2011.
    Current new medicine development at Neusentis consists of small molecule and biologics that modulate
    ion channels, neurotrophins and solute carriers in a range of indications including pain and sensory
    disorders. We also employ stem cell-based technologies to impact either therapeutically or to further our
    understanding of the relevant area of biology (eg disease modelling via differentiation of induced
    pluripotent stem cells derived from patients). The unit also maintains a watching brief on other emerging
    new areas, such as epigenetics and optogenetics. The insight we gain from understanding how to
    modulate both established and novel targets (ion channels, neurotrophins and solute carriers) is also
    helping us to understand the biophysical basis of sensory disorders and explore new ways to develop
    treatments.
    Common to each approach is a process by which we research the mechanisms of the diseases. We then
    decide upon the best approach based on this novel information. This could include defining a new drug
    target, a novel screen to identify molecules that act upon those targets, or it may be to develop a cell
    therapy to restore tissue function. We use state-of-the-art molecular, cell biological, biochemical,
    pharmacological and drug development tools in our quest to discover the medicines of the future.

    ROLE PURPOSE, MAJOR DUTIES AND RESPONSIBILITIES

    As a scientist, you can be sure of a challenging and stimulating year working in an exciting area of science.
    You will work closely with a mentor (an experienced scientist) in addition to being exposed to a
    multidisciplinary, matrixed environment. You will be given the opportunity to develop your own project
    and to learn and use a variety of practical techniques. We have 3 vacancies for a number of disciplines,
    with some project examples as follows: (1) how do specific genes control the differentiation of stem cells
    down a given lineage; (2) establish and perform screens to tease out the role of individual targets as part
    of complex mechanisms and understand their response to novel pharmaceutical agents (3) studying the
    effects of altered trafficking of a solute carrier and how this is modulated by small molecules; (4) in-depth
    molecular characterisation of specific nociceptor subpopulation.







    Pfizer UK Industrial Trainee Scheme 2015/2016

    PERSON SPECIFICATION

    In addition to relevant lab-based skills which could span (but is not limited to) biochemistry, molecular
    biology, pharmacology and cellular biology. In addition, the following attributes would be desirable:
    Enthusiastic, inquisitive, creative, flexible and proactive. Scientifically ambitious, hard-working and takes
    initiative to solve problems. Good team working and communication skills.

    Interested candidates please apply through our website www.pfizercareers.com and select job
    Molecular/Cellular Biology Industrial Trainee (2 positions)-1002420 until October 3
    rd
    2014.

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