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This paper presents the design of folded cascode operational transconductance amplifier (OTA). This design has been implemented in 0.18um CMOS Technology using Cadence. Spectre simulation shows that the OTA has flat gain of 47dB from 1Hz to 100 KHz frequency, indicating stability of OTA, noise ranges as 22.49769nV/ at 10Hz to 66.89128fV/ at 1MHz and average power as 0.770mW. In this paper, we will be studying the design concepts, analysis of operational transconductance amplifier which is used for recording the bio signals. This paper plays a key role in real time applications for equipment designing of ECG, EEG, EMG, ENG devices. It is also used in recording and also for treatment of Paralysis, Epilepsy, Neuro diseases etc.,

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Tuberculosis (TB) is very dangerous and rapidly spread disease in the world. In the investigating cases for suspected tuberculosis (TB), chest radiography is not only the key techniques of diagnosis based on the medical imaging but also the diagnostic radiology. So, Computer aided diagnosis (CAD) has been popular and many researchers are interested in this research areas and different approaches have been proposed for the TB detection and lung decease classification. In this paper, the medical background history of TB decease in chest X-rays and a survey of the various approaches in TB detection and classification are presented. The literature in the related methods is surveyed papers in this research area until now 2014.