Pages that link to "Q60021742"
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The following pages link to The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas (Q60021742):
Displaying 50 items.
- Targeted therapies in sarcomas: challenging the challenge (Q21285014) (← links)
- Vimentin is a novel AKT1 target mediating motility and invasion (Q24300375) (← links)
- Potential for immunotherapy in soft tissue sarcoma (Q27008830) (← links)
- Molecular Targets and Emerging Therapeutic Options for Uterine Leiomyosarcoma (Q28076023) (← links)
- PI3K/PTEN signaling in angiogenesis and tumorigenesis (Q28383083) (← links)
- EGFR inhibition abrogates leiomyosarcoma cell chemoresistance through inactivation of survival pathways and impairment of CSC potential (Q28484249) (← links)
- Vascular PPARgamma controls circadian variation in blood pressure and heart rate through Bmal1 (Q28508879) (← links)
- Down-Regulation of AKT Signalling by Ursolic Acid Induces Intrinsic Apoptosis and Sensitization to Doxorubicin in Soft Tissue Sarcoma (Q28552369) (← links)
- PTEN signaling through RAF1 proto-oncogene serine/threonine kinase (RAF1)/ERK in the epididymis is essential for male fertility (Q28590466) (← links)
- The role of angiogenic factors in fibroid pathogenesis: potential implications for future therapy (Q29040166) (← links)
- Small Is Beautiful: Insulin-Like Growth Factors and Their Role in Growth, Development, and Cancer (Q30395770) (← links)
- Activation of the Akt-mTOR pathway and receptor tyrosine kinase in patients with solitary fibrous tumors (Q33412198) (← links)
- Phase I study and preclinical efficacy evaluation of the mTOR inhibitor sirolimus plus gemcitabine in patients with advanced solid tumours (Q33416342) (← links)
- Discovery of molecular subtypes in leiomyosarcoma through integrative molecular profiling (Q33647672) (← links)
- Oncopig Soft-Tissue Sarcomas Recapitulate Key Transcriptional Features of Human Sarcomas (Q33752789) (← links)
- Biomarker Development for the Clinical Activity of the mTOR Inhibitor Everolimus (RAD001): Processes, Limitations, and Further Proposals (Q33760578) (← links)
- Inhibition of mTORC1 signaling reduces tumor growth but does not prevent cancer progression in a mouse model of thyroid cancer. (Q33947770) (← links)
- Animal models of soft-tissue sarcoma. (Q34098113) (← links)
- The PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models (Q34229795) (← links)
- From PTEN loss of expression to RICTOR role in smooth muscle differentiation: complex involvement of the mTOR pathway in leiomyosarcomas and pleomorphic sarcomas (Q34232192) (← links)
- Soft tissue sarcoma cells are highly sensitive to AKT blockade: a role for p53-independent up-regulation of GADD45 alpha (Q34240979) (← links)
- Inhibition of chondrosarcoma growth by mTOR inhibitor in an in vivo syngeneic rat model (Q34325616) (← links)
- Upregulation of DLX5 promotes ovarian cancer cell proliferation by enhancing IRS-2-AKT signaling (Q34476714) (← links)
- Dystrophin is a tumor suppressor in human cancers with myogenic programs (Q34479070) (← links)
- Inactivation of Patched1 in mice leads to development of gastrointestinal stromal-like tumors that express Pdgfrα but not kit. (Q34510184) (← links)
- Constitutive activation with overexpression of the mTORC2-phospholipase D1 pathway in uterine leiomyosarcoma and STUMP: morphoproteomic analysis with therapeutic implications (Q34566745) (← links)
- Soft tissue sarcomas with complex genomic profiles (Q34617586) (← links)
- Gankyrin is a predictive and oncogenic factor in well-differentiated and dedifferentiated liposarcoma. (Q34619226) (← links)
- Smooth muscle protein-22-mediated deletion of Tsc1 results in cardiac hypertrophy that is mTORC1-mediated and reversed by rapamycin (Q34627013) (← links)
- Epidemiology and therapies for metastatic sarcoma (Q34652142) (← links)
- Mesenchymal stem cell transformation and sarcoma genesis (Q34654560) (← links)
- Inhibition of FOXO1/3 promotes vascular calcification (Q34734532) (← links)
- MLN0128, an ATP-competitive mTOR kinase inhibitor with potent in vitro and in vivo antitumor activity, as potential therapy for bone and soft-tissue sarcoma (Q35096201) (← links)
- Aberrant AKT activation drives well-differentiated liposarcoma (Q35239698) (← links)
- A randomised phase II trial of selumetinib vs selumetinib plus temsirolimus for soft-tissue sarcomas (Q35603657) (← links)
- Potential role of LMP2 as tumor-suppressor defines new targets for uterine leiomyosarcoma therapy. (Q35619604) (← links)
- An immunohistochemical analysis of stathmin 1 expression in uterine smooth muscle tumors: differential expression in leiomyosarcomas and leiomyomas. (Q35632172) (← links)
- Classification, molecular characterization, and the significance of pten alteration in leiomyosarcoma (Q35788748) (← links)
- Mice null for the deubiquitinase USP18 spontaneously develop leiomyosarcomas (Q35837348) (← links)
- PI3K/AKT/mTOR inhibition in combination with doxorubicin is an effective therapy for leiomyosarcoma. (Q35948581) (← links)
- Advances in sarcoma genomics and new therapeutic targets (Q35993346) (← links)
- PTEN hamartoma of soft tissue: a distinctive lesion in PTEN syndromes (Q36008552) (← links)
- Patient with synchronous low grade leiomyosarcoma of the thigh, primary pancreatic neuroendocrine tumor, and lung metastases: Why biopsy of metastases should be the standard (Q36097160) (← links)
- New developments in mammalian target of rapamycin inhibitors for the treatment of sarcoma (Q36144084) (← links)
- Treating metastatic soft-tissue or bone sarcomas - potential role of ridaforolimus (Q36191321) (← links)
- Tanshinone IIA combined with adriamycin inhibited malignant biological behaviors of NSCLC A549 cell line in a synergistic way. (Q36198145) (← links)
- Dual targeting of mTOR and aurora-A kinase for the treatment of uterine Leiomyosarcoma (Q36205257) (← links)
- Alterations of the p53 and PIK3CA/AKT/mTOR pathways in angiosarcomas: a pattern distinct from other sarcomas with complex genomics. (Q36210054) (← links)
- Potential Therapeutic Targets in Uterine Sarcomas. (Q36245677) (← links)
- Involvement of tumor suppressors PTEN and p53 in the formation of multiple subtypes of liposarcoma (Q36288319) (← links)