The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas (Q60021742)

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30 December 2019

title

The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas (English)

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Li Ma

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Robert G. Maki

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Carlos Cordon-Cardo

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Pier Paolo Pandolfi

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Nille Behrendt

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Igor Matushansky

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Igor Matushansky

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Joslyn Mills

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Joslyn Mills

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Elizabeth Charytonowicz

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Elizabeth Charytonowicz

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30 December 2019

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author name string

Maria E Dudas

3

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Silvia Menendez

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Nicholas D Socci

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language of work or name

English

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publication date

13 May 2007

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volume

13

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30 December 2019

issue

6

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30 December 2019

page(s)

748-753

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Mechanisms of sarcoma development

30 December 2019

cites work

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7 January 2021

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

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7 January 2021

IGF2 is critical for tumorigenesis by synovial sarcoma oncoprotein SYT-SSX1

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7 January 2021

Loss of DNA copy number of 10q is associated with aggressive behavior of leiomyosarcomas: a comparative genomic hybridization study

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7 January 2021

Classification and subtype prediction of adult soft tissue sarcoma by functional genomics

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7 January 2021

Pten dose dictates cancer progression in the prostate

1 reference

7 January 2021

High-efficiency somatic mutagenesis in smooth muscle cells and cardiac myocytes in SM22alpha-Cre transgenic mice

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7 January 2021

Criteria for malignancy in nonvisceral smooth muscle tumors.

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7 January 2021

Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis

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7 January 2021

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

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7 January 2021

HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

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7 January 2021

The TOR pathway: a target for cancer therapy

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7 January 2021

mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

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7 January 2021

Mutations in the tuberous sclerosis complex gene TSC2 are a cause of sporadic pulmonary lymphangioleiomyomatosis

1 reference

7 January 2021

Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (TSC2) gene

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7 January 2021

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

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7 January 2021

Mouse mammary tumor virus/v-Ha- ras transgene-induced mammary tumors exhibit strain-specific allelic loss on mouse chromosome 4

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7 January 2021

A mouse model of uterine leiomyosarcoma

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7 January 2021

Smooth muscle-selective deletion of guanylyl cyclase-A prevents the acute but not chronic effects of ANP on blood pressure

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7 January 2021

SM22 alpha, a marker of adult smooth muscle, is expressed in multiple myogenic lineages during embryogenesis

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7 January 2021

Muscle-specific Pten deletion protects against insulin resistance and diabetes

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7 January 2021

Impaired Fas response and autoimmunity in Pten+/- mice

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7 January 2021

T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

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7 January 2021

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

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7 January 2021

MDM2 gene amplification and transcript levels in human sarcomas: relationship to TP53 gene status

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7 January 2021

Identifiers

DOI

10.1038/NM1560

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30 December 2019

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