Germline Variants in Phosphodiesterase Genes and Genetic Predisposition to Pediatric Adrenocortical Tumors (Q89879524)

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9 April 2020

title

Germline Variants in Phosphodiesterase Genes and Genetic Predisposition to Pediatric Adrenocortical Tumors (English)

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9 April 2020

1

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9 April 2020

Elizabeth S Fernandes

5

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9 April 2020

author name string

Fabio R Faucz

2

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9 April 2020

Luana Z Paza

3

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Gang Wu

4

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9 April 2020

Jerome Bertherat

6

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9 April 2020

Constantine A Stratakis

7

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9 April 2020

Enzo Lalli

8

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9 April 2020

Raul C Ribeiro

9

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9 April 2020

Carlos Rodriguez-Galindo

10

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Bonald C Figueiredo

11

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9 April 2020

Gerard P Zambetti

12

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publication date

22 February 2020

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9 April 2020

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volume

12

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issue

2

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Creative Commons Attribution 4.0 International

9 April 2020

copyright license

start time

22 February 2020

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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12 December 2020

Cyclic AMP and cyclic GMP phosphodiesterase activities in Hodgkin's disease lymphocytes

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Characterization of cyclic nucleotide phosphodiesterases with cyclic AMP analogs: topology of the catalytic sites and comparison with other cyclic AMP-binding proteins

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An inherited p53 mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma

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An inherited mutation outside the highly conserved DNA-binding domain of the p53 tumor suppressor protein in children and adults with sporadic adrenocortical tumors

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Adrenal cortical neoplasms in the pediatric population: a clinicopathologic and immunophenotypic analysis of 83 patients

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Cloning of the t(1;5)(q23;q33) in a myeloproliferative disorder associated with eosinophilia: involvement of PDGFRB and response to imatinib

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Founder effect for the highly prevalent R337H mutation of tumor suppressor p53 in Brazilian patients with adrenocortical tumors

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How many genes underlie the occurrence of common complex diseases in the population?

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Cyclic nucleotide phosphodiesterases as targets for treatment of haematological malignancies

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A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia

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Phosphodiesterase genes are associated with susceptibility to major depression and antidepressant treatment response

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Chemoresistant KM12C colon cancer cells are addicted to low cyclic AMP levels in a phosphodiesterase 4-regulated compartment via effects on phosphoinositide 3-kinase

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The p53 mutation "gradient effect" and its clinical implications

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Phosphodiesterase 11A (PDE11A) and genetic predisposition to adrenocortical tumors

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Cyclic nucleotide phosphodiesterase profiling reveals increased expression of phosphodiesterase 7B in chronic lymphocytic leukemia

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Targeted inhibition of cyclic AMP phosphodiesterase-4 promotes brain tumor regression

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Signalling pathway alterations in pituitary adenomas: involvement of Gsalpha, cAMP and mitogen-activated protein kinases.

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Frequent phosphodiesterase 11A gene (PDE11A) defects in patients with Carney complex (CNC) caused by PRKAR1A mutations: PDE11A may contribute to adrenal and testicular tumors in CNC as a modifier of the phenotype

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Mammalian Cyclic Nucleotide Phosphodiesterases: Molecular Mechanisms and Physiological Functions

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Identification of novel genetic variants in phosphodiesterase 8B (PDE8B), a cAMP-specific phosphodiesterase highly expressed in the adrenal cortex, in a cohort of patients with adrenal tumours

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Phosphodiesterases and adrenal Cushing in mice and humans

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Whole-exome sequencing characterizes the landscape of somatic mutations and copy number alterations in adrenocortical carcinoma.

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Prevalence and functional consequence of TP53 mutations in pediatric adrenocortical carcinoma: a children's oncology group study

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Genomic landscape of paediatric adrenocortical tumours

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Phosphodiesterase sequence variants may predispose to prostate cancer

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Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma

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Prkar1a gene knockout in the pancreas leads to neuroendocrine tumorigenesis

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Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome

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12 December 2020

Identification of Clinical and Biologic Correlates Associated With Outcome in Children With Adrenocortical Tumors Without Germline TP53 Mutations: A St Jude Adrenocortical Tumor Registry and Children's Oncology Group Study.

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Phosphodiesterase Inhibitors (PDE Inhibitors) and Male Reproduction

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Multiple cAMP Phosphodiesterases Act Together to Prevent Premature Oocyte Meiosis and Ovulation.

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Metastatic adrenocortical carcinoma displays higher mutation rate and tumor heterogeneity than primary tumors

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Therapeutic targeting of 3',5'-cyclic nucleotide phosphodiesterases: inhibition and beyond

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12 December 2020

Identifiers

DOI

10.3390/CANCERS12020506

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32098292%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

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9 April 2020

PubMed publication ID

32098292

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