Phosphodiesterase sequence variants may predispose to prostate cancer (Q35843428)

10 August 2017

Phosphodiesterase sequence variants may predispose to prostate cancer (English)

1 reference

Rodrigo Bertollo de Alexandre

10 August 2017

Rodrigo B de Alexandre

1

0 references

Dirce Carraro

Dirce M Carraro

8

0 references

Fernando A. Soares

Fernando A Soares

9

0 references

Constantine A Stratakis

11

Constantine A Stratakis

1 reference

10 August 2017

Fabio R Faucz

12

1 reference

ORCID Public Data File 2021

author name string

Anelia D Horvath

2

1 reference

10 August 2017

Eva Szarek

3

1 reference

10 August 2017

Allison D Manning

4

1 reference

10 August 2017

Leticia F Leal

5

1 reference

10 August 2017

Fabio Kardauke

6

1 reference

10 August 2017

Jonathan A Epstein

7

1 reference

10 August 2017

Tatiyana V Apanasovich

10

1 reference

10 August 2017

15 May 2015

1 reference

10 August 2017

Endocrine-Related Cancer

1 reference

10 August 2017

22

1 reference

10 August 2017

4

1 reference

10 August 2017

519-530

1 reference

describes a project that uses

10 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4499475/fullTextXML

inferred from PubMed Central ID database lookup

RStudio

1 reference

18 June 2022

https://europepmc.org/article/PMC/4499475

inferred from PubMed Central ID database lookup

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Downregulation of phosphodiesterase 4B (PDE4B) activates protein kinase A and contributes to the progression of prostate cancer

27 July 2018

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Potential therapeutic applications of phosphodiesterase inhibition in prostate cancer

27 July 2018

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Identification of novel genetic variants in phosphodiesterase 8B (PDE8B), a cAMP-specific phosphodiesterase highly expressed in the adrenal cortex, in a cohort of patients with adrenal tumours

27 July 2018

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27 July 2018

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27 July 2018

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Anti-proliferative effect of curcumin on melanoma cells is mediated by PDE1A inhibition that regulates the epigenetic integrator UHRF1.

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Characterization of differential gene expression in adrenocortical tumors harboring beta-catenin (CTNNB1) mutations

27 July 2018

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27 July 2018

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Phosphodiesterase 11A (PDE11A) genetic variants may increase susceptibility to prostatic cancer

27 July 2018

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A once-daily dose of tadalafil for erectile dysfunction: compliance and efficacy

27 July 2018

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Roles of cAMP and cAMP-dependent protein kinase in the progression of prostate cancer: Cross-talk with the androgen receptor

27 July 2018

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The role of germline AIP, MEN1, PRKAR1A, CDKN1B and CDKN2C mutations in causing pituitary adenomas in a large cohort of children, adolescents, and patients with genetic syndromes.

27 July 2018

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A global map of human gene expression

27 July 2018

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Mutations and polymorphisms in the gene encoding regulatory subunit type 1-alpha of protein kinase A (PRKAR1A): an update

27 July 2018

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Sulindac sulfide selectively inhibits growth and induces apoptosis of human breast tumor cells by phosphodiesterase 5 inhibition, elevation of cyclic GMP, and activation of protein kinase G

27 July 2018

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Phosphodiesterase-5 inhibitors and benign prostatic hyperplasia

27 July 2018

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Oral phosphodiesterase-5 inhibitors and hormonal treatments for erectile dysfunction: a systematic review and meta-analysis

27 July 2018

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Functional phosphodiesterase 11A mutations may modify the risk of familial and bilateral testicular germ cell tumors

27 July 2018

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Overexpressing PKIB in prostate cancer promotes its aggressiveness by linking between PKA and Akt pathways

27 July 2018

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LS-SNP/PDB: annotated non-synonymous SNPs mapped to Protein Data Bank structures.

27 July 2018

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ABCD of the phosphodiesterase family: interaction and differential activity in COPD

27 July 2018

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27 July 2018

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Phosphodiesterase 5 inhibitors in the management of benign prostatic hyperplasia and erectile dysfunction: the best of both worlds

27 July 2018

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Recent advances on phosphodiesterase 4 inhibitors for the treatment of asthma and chronic obstructive pulmonary disease

27 July 2018

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Broccoli consumption interacts with GSTM1 to perturb oncogenic signalling pathways in the prostate

27 July 2018

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Phosphodiesterase 11A (PDE11A) and genetic predisposition to adrenocortical tumors

27 July 2018

1 reference

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Phosphodiesterase 11A expression in the adrenal cortex, primary pigmented nodular adrenocortical disease, and other corticotropin-independent lesions.

27 July 2018

1 reference

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Effects of phosphodiesterase-5 inhibitors on sperm parameters and fertilizing capacity

27 July 2018

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Mitogen-activated protein kinase p38 regulates the Wnt/cyclic GMP/Ca2+ non-canonical pathway.

27 July 2018

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27 July 2018

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Adrenal hyperplasia and adenomas are associated with inhibition of phosphodiesterase 11A in carriers of PDE11A sequence variants that are frequent in the population

27 July 2018

1 reference

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A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia

27 July 2018

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Serial analysis of gene expression in adrenocortical hyperplasia caused by a germline PRKAR1A mutation

27 July 2018

1 reference

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Characterization and prediction of alternative splice sites

27 July 2018

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Phosphodiesterase 3A binds to 14-3-3 proteins in response to PMA-induced phosphorylation of Ser428.

27 July 2018

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Regulation of cyclic nucleotides in the urinary tract

27 July 2018

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PDE6 is an effector for the Wnt/Ca2+/cGMP-signalling pathway in development

27 July 2018

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Characteristics of photoreceptor PDE (PDE6): similarities and differences to PDE5

27 July 2018

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Genomic variants in exons and introns: identifying the splicing spoilers

27 July 2018

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Three-dimensional structures of PDE4D in complex with roliprams and implication on inhibitor selectivity

27 July 2018

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A phosphatidylinositol 3-kinase phosphodiesterase 3B-cyclic AMP pathway in hypothalamic action of leptin on feeding

27 July 2018

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Sub-family selective actions in the ability of Erk2 MAP kinase to phosphorylate and regulate the activity of PDE4 cyclic AMP-specific phosphodiesterases

27 July 2018

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Cloning and characterization of the human and mouse PDE7B, a novel cAMP-specific cyclic nucleotide phosphodiesterase

27 July 2018

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ERK2 mitogen-activated protein kinase binding, phosphorylation, and regulation of the PDE4D cAMP-specific phosphodiesterases. The involvement of COOH-terminal docking sites and NH2-terminal UCR regions

27 July 2018

1 reference

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Molecular cloning and characterization of a distinct human phosphodiesterase gene family: PDE11A

27 July 2018

1 reference

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Cloning and characterization of a novel human phosphodiesterase that hydrolyzes both cAMP and cGMP (PDE10A)

27 July 2018

1 reference

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cAMP-specific phosphodiesterase HSPDE4D3 mutants which mimic activation and changes in rolipram inhibition triggered by protein kinase A phosphorylation of Ser-54: generation of a molecular model.

27 July 2018

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Improved Splice Site Detection in Genie

27 July 2018

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Splice site prediction in Arabidopsis thaliana pre-mRNA by combining local and global sequence information

27 July 2018

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Heterozygous mutations in cyclic AMP phosphodiesterase-4D (PDE4D) and protein kinase A (PKA) provide new insights into the molecular pathology of acrodysostosis.

27 July 2018

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MutationTaster2: mutation prediction for the deep-sequencing age.

24 September 2018

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Etazolate abrogates the lipopolysaccharide (LPS)-induced downregulation of the cAMP/pCREB/BDNF signaling, neuroinflammatory response and depressive-like behavior in mice.

24 September 2018

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Cancer therapy combination: green tea and a phosphodiesterase 5 inhibitor?

24 September 2018

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Inhibitory effects and underlying mechanism of 7-hydroxyflavone phosphate ester in HeLa cells

24 September 2018

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An exon-specific U1 small nuclear RNA (snRNA) strategy to correct splicing defects

24 September 2018

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Frequent phosphodiesterase 11A gene (PDE11A) defects in patients with Carney complex (CNC) caused by PRKAR1A mutations: PDE11A may contribute to adrenal and testicular tumors in CNC as a modifier of the phenotype

24 September 2018

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cGMP-phosphodiesterase 6, transducin and Wnt5a/Frizzled-2-signaling control cGMP and Ca(2+) homeostasis in melanoma cells

24 September 2018

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Enhanced antiproliferative and proapoptotic effects on prostate cancer cells by simultaneously inhibiting androgen receptor and cAMP-dependent protein kinase A.

24 September 2018

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Lack of direct androgen regulation of PDE5 expression

24 September 2018

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STRING 8--a global view on proteins and their functional interactions in 630 organisms

24 September 2018

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Large deletions of the PRKAR1A gene in Carney complex

24 September 2018

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Large-scale comparative analysis of splicing signals and their corresponding splicing factors in eukaryotes

24 September 2018

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Suppression of cyclic GMP-specific phosphodiesterase 5 promotes apoptosis and inhibits growth in HT29 cells

24 September 2018

1 reference

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Protein kinase G II-mediated proliferative effects in human cultured prostatic stromal cells

24 September 2018

1 reference

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Regulation and function of the cyclic nucleotide phosphodiesterase (PDE3) gene family

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4499475

Cloning and characterization of PDE7B, a cAMP-specific phosphodiesterase

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4499475

Inhibition of smooth muscle cell growth by nitric oxide and activation of cAMP-dependent protein kinase by cGMP

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4499475

Biobanking practice: RNA storage at low concentration affects integrity

24 September 2018

1 reference

12 December 2020

Pre-clinical evidence for the use of phosphodiesterase-5 inhibitors for treating benign prostatic hyperplasia and lower urinary tract symptoms

1 reference

12 December 2020

Inhibition of phosphodiesterase 11 (PDE11) impacts on sperm quality

1 reference

12 December 2020

The phosphodiesterase 5 inhibitor sildenafil stimulates angiogenesis through a protein kinase G/MAPK pathway

1 reference

12 December 2020

Protein kinase G mediates vascular endothelial growth factor-induced Raf-1 activation and proliferation in human endothelial cells

1 reference

12 December 2020

Identifiers

DOI

10.1530/ERC-15-0134

1 reference

10 August 2017

1 reference

10 August 2017

PubMed publication ID

25979379

1 reference