Transcription factor NFE2L2/NRF2 modulates chaperone-mediated autophagy through the regulation of LAMP2A (Q61843146)

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2 April 2020

title

Transcription factor NFE2L2/NRF2 modulates chaperone-mediated autophagy through the regulation of LAMP2A (English)

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2

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5

Ana María Cuervo

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2 April 2020

Esperanza Arias

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ORCID Public Data File 2021

author name string

Marta Pajares

series ordinal

1

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2 April 2020

Antonio Díaz-Carretero

series ordinal

4

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Antonio Cuadrado

series ordinal

6

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language of work or name

English

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publication date

26 July 2018

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volume

14

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issue

8

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page(s)

1310-1322

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ImageJ

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11 June 2022

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inferred from PubMed Central ID database lookup

cites work

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Regulation of lamp2a levels in the lysosomal membrane

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Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression

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Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid

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Regulation of Cu/Zn-Superoxide Dismutase Expression via the Phosphatidylinositol 3 Kinase/Akt Pathway and Nuclear Factor- B

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Unifying nomenclature for the isoforms of the lysosomal membrane protein LAMP-2.

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Altered dynamics of the lysosomal receptor for chaperone-mediated autophagy with age.

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Identification of polymorphic antioxidant response elements in the human genome

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Molecular basis distinguishing the DNA binding profile of Nrf2-Maf heterodimer from that of Maf homodimer

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In silico detection of sequence variations modifying transcriptional regulation

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Constitutive activation of chaperone-mediated autophagy in cells with impaired macroautophagy

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The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane

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Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function

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Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease.

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p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription

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A photoconvertible fluorescent reporter to track chaperone-mediated autophagy

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Astrocyte-specific overexpression of Nrf2 delays motor pathology and synuclein aggregation throughout the CNS in the alpha-synuclein mutant (A53T) mouse model

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Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52.

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Chaperone-mediated autophagy regulates T cell responses through targeted degradation of negative regulators of T cell activation

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Loss of hepatic chaperone-mediated autophagy accelerates proteostasis failure in aging

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Regulated degradation of Chk1 by chaperone-mediated autophagy in response to DNA damage

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12 December 2020

Lysosomal mTORC2/PHLPP1/Akt Regulate Chaperone-Mediated Autophagy

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12 December 2020

Epigallocatechin-3-gallate enhances clearance of phosphorylated tau in primary neurons

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12 December 2020

Redox control of protein degradation

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12 December 2020

LAMP-2C Inhibits MHC Class II Presentation of Cytoplasmic Antigens by Disrupting Chaperone-Mediated Autophagy

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12 December 2020

Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes.

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12 December 2020

Methods to Study Chaperone-Mediated Autophagy

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12 December 2020

10.1080/15548627.2018.1474992

Identifiers

DOI

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2 April 2020

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2 April 2020

PubMed publication ID

29950142

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