Early T cell differentiation lessons from T-cell acute lymphoblastic leukemia (Q50671106)

17 March 2018

review article

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title

Early T cell differentiation lessons from T-cell acute lymphoblastic leukemia (English)

1 reference

17 March 2018

1 reference

1 reference

3

Trang Hoang

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17 March 2018

author name string

Cédric S Tremblay

series ordinal

1

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17 March 2018

Thu Hoang

series ordinal

2

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17 March 2018

publication date

1 January 2010

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17 March 2018

Progress in Molecular Biology and Translational Science

published in

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17 March 2018

volume

92

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17 March 2018

page(s)

121-156

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17 March 2018

Commitment and developmental potential of extrathymic and intrathymic T cell precursors: plenty to choose from

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The tumor suppressor PTEN regulates T cell survival and antigen receptor signaling by acting as a phosphatidylinositol 3-phosphatase

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https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

TAL1/SCL induces leukemia by inhibiting the transcriptional activity of E47/HEB.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

The dynamics of T cell receptor signaling: complex orchestration and the key roles of tempo and cooperation

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Signal transduction mediated by the T-cell antigen receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

On the role of self-recognition in T cell responses to foreign antigen

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Alterations of the p53, p21, p16, p15 and RAS genes in childhood T-cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Mutational analysis of the N-ras gene in acute lymphoblastic leukemia: a study of 125 Japanese pediatric cases

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Inefficient ZAP-70 phosphorylation and decreased thymic selection in vivo result from inhibition of NF-kappaB/Rel

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

The calcineurin/NFAT signaling pathway: a novel therapeutic target in leukemia and solid tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Cytogenetic studies in T-cell acute lymphoblastic leukemia (1981-2002).

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Notch1-dependent lymphomagenesis is assisted by but does not essentially require pre-TCR signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Pre-TCR expression cooperates with TEL-JAK2 to transform immature thymocytes and induce T-cell leukemia.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

p16INK4A tumor suppressor gene expression and CD3epsilon deficiency but not pre-TCR deficiency inhibit TAL1-linked T-lineage leukemogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

No requirement for V(D)J recombination in p53-deficient thymic lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

The gene expression signature of relapse in paediatric acute lymphoblastic leukaemia: implications for mechanisms of therapy failure.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Translating microarray data for diagnostic testing in childhood leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Identification of novel molecular prognostic markers for paediatric T-cell acute lymphoblastic leukaemia.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

A global test for groups of genes: testing association with a clinical outcome

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

The biology of human CD2.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

CD2 molecules redistribute to the uropod during T cell scanning: implications for cellular activation and immune surveillance

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Molecular pathogenesis of T-cell leukaemia and lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Novel molecular and cellular therapeutic targets in acute lymphoblastic leukemia and lymphoproliferative disease

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Critical roles of the PI3K/Akt signaling pathway in T cell development

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

PTEN mutations in endometrial carcinomas: a molecular and clinicopathologic analysis of 38 cases

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Association of splicing defects in PTEN leading to exon skipping or partial intron retention in Cowden syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

The role of the PTEN/AKT Pathway in NOTCH1-induced leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

High-resolution genomic profiling of childhood T-ALL reveals frequent copy-number alterations affecting the TGF-beta and PI3K-AKT pathways and deletions at 6q15-16.1 as a genomic marker for unfavorable early treatment response

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Regulation of PTEN by CK2 and Notch1 in primary T-cell acute lymphoblastic leukemia: rationale for combined use of CK2- and gamma-secretase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and downstream signaling in pediatric T-cell acute lymphoblastic leukemia: a report from the Children's Oncology Group

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Notch-1 associates with IKKalpha and regulates IKK activity in cervical cancer cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Integration of Notch 1 and calcineurin/NFAT signaling pathways in keratinocyte growth and differentiation control.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Targeted therapy in T-cell malignancies: dysregulation of the cellular signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Mining for JAK-STAT mutations in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

A requirement for sustained ERK signaling during thymocyte positive selection in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Targeting calcineurin activation as a therapeutic strategy for T-cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

A long twentieth century of the cell cycle and beyond

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

p16 INK4 Mutations and Altered Expression in Human Tumors and Cell Lines

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Overexpression of the Helix-Loop-Helix protein Id2 blocks T cell development at multiple stages.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

E2A and HEB are required to block thymocyte proliferation prior to pre-TCR expression

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

E2A Deficiency Leads to Abnormalities in αβ T-Cell Development and to Rapid Development of T-Cell Lymphomas

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Gradient of E2A activity in B-cell development

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Regulation of the Expression of Cyclin-Dependent Kinase Inhibitor p21 by E2A and Id Proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Gene expression patterns define novel roles for E47 in cell cycle progression, cytokine-mediated signaling, and T lineage development

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

The role of the Ikaros gene in lymphocyte development and homeostasis

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

The Ikaros gene is required for the development of all lymphoid lineages

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Ikaros regulates Notch target gene expression in developing thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Genetic inactivation of Ikaros is a rare event in human T-ALL

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Inactivation of LEF1 in T-cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Redundant Regulation of T Cell Differentiation and TCRα Gene Expression by the Transcription Factors LEF-1 and TCF-1

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Leukemia-associated NF1 inactivation in patients with pediatric T-ALL and AML lacking evidence for neurofibromatosis

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Somatic inactivation of Nf1 in hematopoietic cells results in a progressive myeloproliferative disorder

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Homozygous inactivation of the NF1 gene in bone marrow cells from children with neurofibromatosis type 1 and malignant myeloid disorders

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Ras signaling and NF1.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Overexpression of the myeloid leukemia-associated Hoxa9 gene in bone marrow cells induces stem cell expansion

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Conditional c-myb knockout in adult hematopoietic stem cells leads to loss of self-renewal due to impaired proliferation and accelerated differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Adult hematopoietic stem and progenitor cells require either Lyl1 or Scl for survival

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

From stem cell to T cell: one route or many?

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

The Lmo2 oncogene initiates leukemia in mice by inducing thymocyte self-renewal

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Of mice and men: how an oncogene transgresses the limits and predisposes to T cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

Thymic selection revisited: how essential is it?

1 reference

https://api.crossref.org/works/10.1016%2FS1877-1173%2810%2992006-1

7 January 2021

10.1016/S1877-1173(10)92006-1

Identifiers

DOI

1 reference

17 March 2018

1 reference

17 March 2018