Thymic selection revisited: how essential is it? (Q35076679)

6 August 2017

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title

Thymic selection revisited: how essential is it? (English)

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6 August 2017

2

Iannis Aifantis

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6 August 2017

1

Harald von Boehmer

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6 August 2017

Fotini Gounari

3

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6 August 2017

Orly Azogui

4

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6 August 2017

Loralee Haughn

5

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6 August 2017

Irina Apostolou

6

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6 August 2017

Elmar Jaeckel

7

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6 August 2017

Fabio Grassi

8

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6 August 2017

Ludger Klein

9

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6 August 2017

publication date

1 February 2003

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6 August 2017

published in

Immunological Reviews

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6 August 2017

volume

191

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6 August 2017

page(s)

62-78

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H-2 antigens of the thymus determinelymphocyte specificity

6 August 2017

cites work

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21 January 2018

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In a fully H-2 incompatible chimera, T cells of donor origin can respond to minor histocompatibility antigens in association with either donor or host H-2 type

21 January 2018

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Restriction specificities, alloreactivity, and allotolerance expressed by T cells from nude mice reconstituted with H-2-compatible or -incompatible thymus grafts

21 January 2018

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Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice

21 January 2018

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Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand.

21 January 2018

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Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor

21 January 2018

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Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

21 January 2018

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Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen

21 January 2018

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Clonal deletion of immature CD4+8+ thymocytes in suspension culture by extrathymic antigen-presenting cells

21 January 2018

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Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells.

21 January 2018

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RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

21 January 2018

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Developmental biology of T cells in T cell-receptor transgenic mice

21 January 2018

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Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages

21 January 2018

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Structure and function of the pre-T cell receptor

21 January 2018

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Early T lymphocyte progenitors

21 January 2018

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Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus.

21 January 2018

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Identification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow

21 January 2018

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Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation

21 January 2018

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Notch signaling: cell fate control and signal integration in development

21 January 2018

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Direct induction of T lymphocyte-specific gene expression by the mammalian Notch signaling pathway

21 January 2018

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On the dynamics of TCR:CD3 complex cell surface expression and downmodulation

21 January 2018

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Constitutive endocytosis and degradation of the pre-T cell receptor.

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

alpha beta T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Activated Ras signals differentiation and expansion of CD4+8+ thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

On the brink of becoming a T cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Positive and negative regulation of T-cell activation by adaptor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Essential and partially overlapping role of CD3gamma and CD3delta for development of alphabeta and gammadelta T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

The absence of Itk inhibits positive selection without changing lineage commitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Pleiotropic changes controlled by the pre-T-cell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

FADD/MORT1 regulates the pre-TCR checkpoint and can function as a tumour suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Somatic activation of beta-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

The CD3-gammadeltaepsilon and CD3-zeta/eta modules are each essential for allelic exclusion at the T cell receptor beta locus but are both dispensable for the initiation of V to (D)J recombination at the T cell receptor-beta, -gamma, and -delta loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Allelic exclusion and differentiation by protein kinase C-mediated signals in immature thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Different initiation of pre-TCR and gammadeltaTCR signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Role of different T cell receptors in the development of pre-T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Premature expression of T cell receptor (TCR)alphabeta suppresses TCRgammadelta gene rearrangement but permits development of gammadelta lineage T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Evidence that gammadelta versus alphabeta T cell fate determination is initiated independently of T cell receptor signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Biased V beta usage in immature thymocytes is independent of DJ beta proximity and pT alpha pairing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Separation of Notch1 promoted lineage commitment and expansion/transformation in developing T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Exclusion and inclusion of α and β T cell receptor alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

The role of recombination activating gene (RAG) reinduction in thymocyte development in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

The tight interallelic positional coincidence that distinguishes T-cell receptor Jalpha usage does not result from homologous chromosomal pairing during ValphaJalpha rearrangement

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Evaluation of the percentage of peripheral T cells with two different T cell receptor alpha-chains and of their potential role in autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Expression of a second receptor rescues self-specific T cells from thymic deletion and allows activation of autoreactive effector function

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Dual receptor T cells extend the immune repertoire for foreign antigens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Rapid deletion of rearranged T cell antigen receptor (TCR) Valpha-Jalpha segment by secondary rearrangement in the thymus: role of continuous rearrangement of TCR alpha chain gene and positive selection in the T cell repertoire formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

The MHC reactivity of the T cell repertoire prior to positive and negative selection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

How Many Thymocytes Audition for Selection?

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Evidence for a differential avidity model of T cell selection in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

T cell receptor antagonist peptides induce positive selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Csk controls antigen receptor-mediated development and selection of T-lineage cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Positive selection of CD4+ T cells by TCR ligation without aggregation even in the absence of MHC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Murine CD1d-restricted T cell recognition of cellular lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Mouse CD1-specific NK1 T cells: development, specificity, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Negative selection in the thymus includes semimature T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Promiscuous gene expression and central T-cell tolerance: more than meets the eye.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Pancreatic gene expression in rare cells of thymic medulla: evidence for functional contribution to T cell tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

CD4 T cell tolerance to human C-reactive protein, an inducible serum protein, is mediated by medullary thymic epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

The third function of the thymus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

21 January 2018

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The danger model: a renewed sense of self

21 January 2018

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Innate immune recognition: mechanisms and pathways

21 January 2018

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Positional cloning of the APECED gene

21 January 2018

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Aire deficient mice develop multiple features of APECED phenotype and show altered immune response

21 January 2018

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

T cell tolerance by clonal elimination in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Failure of HY-Specific Thymocytes to Escape Negative Selection by Receptor Editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Positive selection of antigen-specific T cells in thymus by restricting MHC molecules

21 January 2018

1 reference

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The generation of mature T cells requires interaction of the αβ T-cell receptor with major histocompatibility antigens

21 January 2018

1 reference

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Crucial role of the pre-T-cell receptor α gene in development of ap but not γδ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

NF-kappa B activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Premature TCR alpha beta expression and signaling in early thymocytes impair thymocyte expansion and partially block their development

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Changes in the VH Gene Repertoire of Developing Precursor B Lymphocytes in Mouse Bone Marrow Mediated by the Pre-B Cell Receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Receptor editing in developing T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

A season for midwinter immunology

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Intrathymic expression of genes involved in organ specific autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

Major histocompatibility complex-linked immune-responsiveness is acquired by lymphocytes of low-responder mice differentiating in thymus of high-responder mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

The role of H-2 linked genes in helper T-cell function. IV. Importance of T-cell genotype and host environment in I-region and Ir gene expression

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https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

The T-cell receptor for antigen in T-cell development and repertoire selection

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Clonal deletion induced by either radioresistant thymic host cells or lymphohemopoietic donor cells at different stages of class I-restricted T cell ontogeny

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Mice lacking MHC class II molecules

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Analysis and expression of a cloned pre-T cell receptor gene

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

A novel disulfide-linked heterodimer on pre-T cells consists of the T cell receptor beta chain and a 33 kd glycoprotein

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Combined deletion of CD8 locus cis-regulatory elements affects initiation but not maintenance of CD8 expression.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Deficient T cell fate specification in mice with an induced inactivation of Notch1.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Notch1 expression in early lymphopoiesis influences B versus T lineage determination

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Developmental regulation of T-cell receptor gene expression

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Expression of T-cell antigen receptor genes during fetal development in the thymus

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

The impact of pre-T-cell receptor signals on gene expression in developing T cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Involvement of the protein tyrosine kinase p56lck in T cell signaling and thymocyte development.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Constitutive pre-TCR signaling promotes differentiation through Ca2+ mobilization and activation of NF-kappaB and NFAT

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Pre-TCR signaling and inactivation of p53 induces crucial cell survival pathways in pre-T cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Essential Role of the Pre-T Cell Receptor in Allelic Exclusion of the T Cell Receptor β Locus

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Immature thymocytes employ distinct signaling pathways for allelic exclusion versus differentiation and expansion

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Distinct signals mediate maturation and allelic exclusion in lymphocyte progenitors

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

The alpha beta T cell receptor can replace the gamma delta receptor in the development of gamma delta lineage cells.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

An unusual lineage of alpha/beta T cells that contains autoreactive cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Alpha beta and gamma delta T cells can share a late common precursor

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

In-frame TCR delta gene rearrangements play a critical role in the alpha beta/gamma delta T cell lineage decision

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Evidence that productive rearrangements of TCR gamma genes influence the commitment of progenitor cells to differentiate into alpha beta or gamma delta T cells.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

On the role of the pre-T cell receptor in alphabeta versus gammadelta T lineage commitment

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Cellular competition modulates survival and selection of CD8+ T cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

The joining of germ-line V alpha to J alpha genes replaces the preexisting V alpha-J alpha complexes in a T cell receptor alpha, beta positive T cell line.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

A T cell clone expresses two T cell receptor alpha genes but uses one alpha beta heterodimer for allorecognition and self MHC-restricted antigen recognition

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Multiple rearrangements in T cell receptor alpha chain genes maximize the production of useful thymocytes

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

T cell receptor genes in a series of class I major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a Plasmodium berghei nonapeptide: implications for T cell allelic exclusion and antigen-specific repertoire

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Expression of two T cell receptor α chains on the surface of normal murine T cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Allelic inclusion of T cell receptor alpha genes poses an autoimmune hazard due to low-level expression of autospecific receptors

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Non-obese diabetic mice hemizygous at the T cell receptor alpha locus are susceptible to diabetes and sialitis.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Dual T cell receptor alpha chain T cells in autoimmunity

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Developmental regulation of B lymphocyte immune tolerance compartmentalizes clonal selection from receptor selection.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Thymocyte Expression of RAG-1 and RAG-2: Termination by T Cell Receptor Cross-Linking

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

The influence of positive selection on RAG expression in thymocytes

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

In a radiation chimaera, host H–2 antigens determine immune responsiveness of donor cytotoxic cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Positive and negative thymocyte selection induced by different concentrations of a single peptide

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Positive selection of CD8+ T cells induced by major histocompatibility complex binding peptides in fetal thymic organ culture

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

T-cell development and the CD4-CD8 lineage decision

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

An activated lck transgene promotes thymocyte development in RAG-1 mutant mice.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Lck activity controls CD4/CD8 T cell lineage commitment.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Signals through CD8 or CD4 can induce commitment to the CD4 lineage in the thymus

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Intrathymic T cell receptor (TcR) targeting in mice lacking CD4 or major histocompatibility complex (MHC) class II: rescue of CD4 T cell lineage without co-engagement of TcR/CD4 by MHC class II.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Coreceptor reversal in the thymus: signaled CD4+8+ thymocytes initially terminate CD8 transcription even when differentiating into CD8+ T cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Thymocyte development in major histocompatibility complex-deficient mice: evidence for stochastic commitment to the CD4 and CD8 lineages

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Variegated expression of CD8 alpha resulting from in situ deletion of regulatory sequences.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Antigen-presenting function of the TL antigen and mouse CD1 molecules.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Positive selection of an H2-M3 restricted T cell receptor

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Positive selection of a Qa-1-restricted T cell receptor with specificity for insulin

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Positive selection of MHC class Ib-restricted CD8(+) T cells on hematopoietic cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

CD69 expression during selection and maturation of CD4+8+ thymocytes.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

T-cell tolerance toward a transgenic beta-cell antigen and transcription of endogenous pancreatic genes in thymus

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Tolerance induced by thymic epithelial grafts in birds

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Lymphocytes selected in allogeneic thymic epithelium mediate dominant tolerance toward tissue grafts of the thymic epithelium haplotype

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

CD4+ CD25+ suppressor T cells: more questions than answers

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Origin of regulatory T cells with known specificity for antigen

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

Projection of an immunological self shadow within the thymus by the aire protein

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00010.X

7 January 2021

10.1034/J.1600-065X.2003.00010.X

Identifiers

DOI

1 reference

6 August 2017

1 reference