Mutant Huntingtin induces activation of the Bcl-2/adenovirus E1B 19-kDa interacting protein (BNip3) (Q39757740)

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24 January 2020

title

Mutant Huntingtin induces activation of the Bcl-2/adenovirus E1B 19-kDa interacting protein (BNip3) (English)

1 reference

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24 January 2020

1 reference

6

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24 January 2020

Vincenzo Silani

9

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24 January 2020

author name string

J Sassone

1

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24 January 2020

C Colciago

2

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24 January 2020

P Marchi

3

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24 January 2020

C Ascardi

4

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24 January 2020

L Alberti

5

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24 January 2020

R Zippel

7

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24 January 2020

S Sipione

8

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24 January 2020

A Ciammola

10

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24 January 2020

publication date

1 January 2010

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24 January 2020

published in

Cell Death and Disease

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24 January 2020

volume

1

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24 January 2020

page(s)

e7

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Mitochondria and Huntington's disease pathogenesis: insight from genetic and chemical models

24 January 2020

cites work

1 reference

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Mutant huntingtin and mitochondrial dysfunction

22 September 2017

1 reference

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Inhibition of ischemic cardiomyocyte apoptosis through targeted ablation of Bnip3 restrains postinfarction remodeling in mice

22 September 2017

1 reference

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The role of the hypoxia-inducible BH3-only proteins BNIP3 and BNIP3L in cancer

22 September 2017

1 reference

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Unique dimeric structure of BNip3 transmembrane domain suggests membrane permeabilization as a cell death trigger

22 September 2017

1 reference

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Acidosis regulates the stability, hydrophobicity, and activity of the BH3-only protein Bnip3.

22 September 2017

1 reference

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Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy

22 September 2017

1 reference

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Regulation of BNIP3 in normal and cancer cells.

22 September 2017

1 reference

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Involvement of mitochondrial complex II defects in neuronal death produced by N-terminus fragment of mutated huntingtin

22 September 2017

1 reference

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Severe ultrastructural mitochondrial changes in lymphoblasts homozygous for Huntington disease mutation

22 September 2017

1 reference

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The pro-cell death Bcl-2 family member, BNIP3, is localized to the nucleus of human glial cells: Implications for glioblastoma multiforme tumor cell survival under hypoxia

22 September 2017

1 reference

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Membrane translocation and oligomerization of hBok are triggered in response to apoptotic stimuli and Bnip3

22 September 2017

1 reference

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BNip3 and signal-specific programmed death in the heart

22 September 2017

1 reference

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A unique pathway of cardiac myocyte death caused by hypoxia-acidosis.

22 September 2017

1 reference

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BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF.

22 September 2017

1 reference

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Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3.

22 September 2017

1 reference

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The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability

22 September 2017

1 reference

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BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore

22 September 2017

1 reference

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BNIP3 heterodimerizes with Bcl-2/Bcl-X(L) and induces cell death independent of a Bcl-2 homology 3 (BH3) domain at both mitochondrial and nonmitochondrial sites

22 September 2017

1 reference

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Regulated targeting of BAX to mitochondria.

22 September 2017

1 reference

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The E1B 19K/Bcl-2–binding Protein Nip3 is a Dimeric Mitochondrial Protein that Activates Apoptosis

22 September 2017

1 reference

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Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

22 September 2017

1 reference

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Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.

22 September 2017

1 reference

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Increased apoptosis, Huntingtin inclusions and altered differentiation in muscle cell cultures from Huntington's disease subjects

25 September 2017

1 reference

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The carboxy terminal C-tail of BNip3 is crucial in induction of mitochondrial permeability transition in isolated mitochondria

15 June 2018

1 reference

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Evidence of apoptosis and mitochondrial abnormalities in peripheral blood cells of Huntington's disease patients.

15 June 2018

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Regulation of mitochondrial integrity, autophagy and cell survival by BNIP3.

20 August 2018

1 reference

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Bnip3 mediates mitochondrial dysfunction and cell death through Bax and Bak.

20 August 2018

1 reference

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HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism

20 August 2018

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p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease

20 August 2018

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Mitochondrial impairment in patients and asymptomatic mutation carriers of Huntington's disease

20 August 2018

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In vitro effects of polyglutamine tracts on Ca2+-dependent depolarization of rat and human mitochondria: relevance to Huntington's disease.

20 August 2018

1 reference

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Inducible expression of BNIP3 provokes mitochondrial defects and hypoxia-mediated cell death of ventricular myocytes

20 August 2018

1 reference

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Abnormal in vivo skeletal muscle energy metabolism in Huntington's disease and dentatorubropallidoluysian atrophy

20 August 2018

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A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

20 August 2018

1 reference

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Biochemical abnormalities and excitotoxicity in Huntington's disease brain.

20 August 2018

1 reference

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Complex I defect in muscle from patients with Huntington's disease.

20 August 2018

1 reference

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Mitochondrial defect in Huntington's disease caudate nucleus

20 August 2018

1 reference

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Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21364626

12 December 2020

inferred from PubMed ID database lookup

Regulation of Bnip3 death pathways by calcium, phosphorylation, and hypoxia-reoxygenation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21364626

12 December 2020

inferred from PubMed ID database lookup

Correction of hemophilia B in canine and murine models using recombinant adeno-associated viral vectors

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FCDDIS.2009.6

7 January 2021

inferred from DOI database lookup

Reevaluation of the PPAR-β/δ Ligand Binding Domain Model Reveals Why It Exhibits the Activated Form

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FCDDIS.2009.6

7 January 2021

inferred from DOI database lookup

Abnormal in vivo skeletal muscle energy metabolism in Huntington's disease and dentatorubropallidoluysian atrophy

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FCDDIS.2009.6

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/CDDIS.2009.6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21364626%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference

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24 January 2020

PubMed publication ID

21364626

1 reference