Autoinhibition of the kit receptor tyrosine kinase by the cytosolic juxtamembrane region. (Q39745856)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12697809%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

title

Autoinhibition of the kit receptor tyrosine kinase by the cytosolic juxtamembrane region (English)

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2 November 2019

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4

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2 November 2019

Robert Rottapel

5

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2 November 2019

author name string

Perry M Chan

1

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2 November 2019

Subburaj Ilangumaran

2

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2 November 2019

Jose La Rose

3

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2 November 2019

language of work or name

English

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publication date

1 May 2003

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Molecular and Cellular Biology

2 November 2019

published in

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2 November 2019

volume

23

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2 November 2019

issue

9

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2 November 2019

page(s)

3067-3078

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describes a project that uses

2 November 2019

ImageQuant

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11 June 2022

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inferred from PubMed Central ID database lookup

cites work

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Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region

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Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch

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Phosphorylation of tyrosine residues in the kinase domain and juxtamembrane region regulates the biological and catalytic activities of Eph receptors

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Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12

14 September 2017

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A single amino acid substitution in a WW-like domain of diverse members of the PDGF receptor subfamily of tyrosine kinases causes constitutive receptor activation

14 September 2017

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SHP-1 binds and negatively modulates the c-Kit receptor by interaction with tyrosine 569 in the c-Kit juxtamembrane domain

14 September 2017

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Gain-of-Function Mutations of c- kit in Human Gastrointestinal Stromal Tumors

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Lyn Associates with the Juxtamembrane Region of c-Kit and Is Activated by Stem Cell Factor in Hematopoietic Cell Lines and Normal Progenitor Cells

14 September 2017

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Direct association of Csk homologous kinase (CHK) with the diphosphorylated site Tyr568/570 of the activated c-KIT in megakaryocytes

14 September 2017

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Crystal structure of the Src family tyrosine kinase Hck

14 September 2017

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Three-dimensional structure of the tyrosine kinase c-Src

14 September 2017

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Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism

14 September 2017

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Tyrosine 569 in the c-Fms juxtamembrane domain is essential for kinase activity and macrophage colony-stimulating factor-dependent internalization

14 September 2017

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14 September 2017

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Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product

14 September 2017

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Tyrosine residue 719 of the c-kit receptor is essential for binding of the P85 subunit of phosphatidylinositol (PI) 3-kinase and for c-kit-associated PI 3-kinase activity in COS-1 cells

14 September 2017

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14 September 2017

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14 September 2017

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A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 3'-kinase activation and endothelial cell migration

14 September 2017

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14 September 2017

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14 September 2017

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25 September 2017

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17 June 2018

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17 June 2018

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17 June 2018

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Characterization of pp60c-src Tyrosine Kinase Activities Using a Continuous Assay: Autoactivation of the Enzyme Is an Intermolecular Autophosphorylation Process

20 August 2018

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12 December 2020

Internal tandem duplication of the flt3 gene found in acute myeloid leukemia

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12 December 2020

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12 December 2020

Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines

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12 December 2020

10.1128/MCB.23.9.3067-3078.2003

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12697809%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12697809%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

PubMed publication ID

12697809

1 reference