Full activation of the platelet-derived growth factor beta-receptor kinase involves multiple events (Q42457318)

31 October 2017

title

Full activation of the platelet-derived growth factor beta-receptor kinase involves multiple events (English)

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31 October 2017

R M Baxter

1

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31 October 2017

J P Secrist

series ordinal

2

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31 October 2017

R R Vaillancourt

series ordinal

3

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31 October 2017

A Kazlauskas

series ordinal

4

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31 October 2017

language of work or name

English

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publication date

1 July 1998

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Journal of Biological Chemistry

31 October 2017

published in

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31 October 2017

volume

273

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31 October 2017

issue

27

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31 October 2017

page(s)

17050-17055

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Dimerization of cell surface receptors in signal transduction

31 October 2017

cites work

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Signal transduction by receptors with tyrosine kinase activity

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Regulation of signal transduction and signal diversity by receptor oligomerization

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Mutations of the platelet-derived growth factor receptor that cause a loss of ligand-induced conformational change, subtle changes in kinase activity, and impaired ability to stimulate DNA synthesis

21 January 2018

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Binding of GAP to activated PDGF receptors

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Platelet-derived growth factor (PDGF)-dependent association of phospholipase C-gamma with the PDGF receptor signaling complex

21 January 2018

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Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively

21 January 2018

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Platelet-derived growth factor induces rapid and sustained tyrosine phosphorylation of phospholipase C-gamma in quiescent BALB/c 3T3 cells

21 January 2018

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Oncogenes and signal transduction

21 January 2018

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Role of phosphatidylinositol kinase in PDGF receptor signal transduction

21 January 2018

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Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors

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Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins

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Association between the PDGF receptor and members of the src family of tyrosine kinases

21 January 2018

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Mitogen-activated protein kinase activation is insufficient for growth factor receptor-mediated PC12 cell differentiation

21 January 2018

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Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

21 January 2018

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Protein kinase C mediates platelet-derived growth factor-induced tyrosine phosphorylation of p42.

21 January 2018

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Ligand-independent activation of the platelet-derived growth factor beta receptor: requirements for bovine papillomavirus E5-induced mitogenic signaling

21 January 2018

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Activation of Src Family Members Is Not Required for the Platelet-Derived Growth Factor β Receptor To Initiate Mitogenesis

21 January 2018

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21 January 2018

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Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

21 January 2018

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The GTPase-activating protein of Ras suppresses platelet-derived growth factor beta receptor signaling by silencing phospholipase C-gamma 1

21 January 2018

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Src phosphorylates the insulin-like growth factor type I receptor on the autophosphorylation sites. Requirement for transformation by src.

21 January 2018

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Augmented mitogenic responsiveness to epidermal growth factor in murine fibroblasts that overexpress pp60c-src

21 January 2018

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21 January 2018

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Potentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: implications for the etiology of multiple human cancers

21 January 2018

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Crystal structure of the tyrosine kinase domain of the human insulin receptor

21 January 2018

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Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism

21 January 2018

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Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement

21 January 2018

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Crystal structure of the Src family tyrosine kinase Hck

21 January 2018

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Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.273.27.17050

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31 October 2017

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