Ras induces p21Cip1/Waf1 cyclin kinase inhibitor transcriptionally through Sp1-binding sites (Q38317596)

2 September 2017

title

Ras induces p21Cip1/Waf1 cyclin kinase inhibitor transcriptionally through Sp1-binding sites (English)

1 reference

2 September 2017

L Kivinen

1

1 reference

2 September 2017

M Tsubari

2

1 reference

2 September 2017

T Haapajärvi

3

1 reference

2 September 2017

M B Datto

4

1 reference

2 September 2017

X F Wang

5

1 reference

2 September 2017

M Laiho

6

1 reference

2 September 2017

language of work or name

English

0 references

publication date

1 November 1999

1 reference

2 September 2017

1 reference

2 September 2017

volume

18

1 reference

2 September 2017

issue

46

1 reference

2 September 2017

page(s)

6252-6261

1 reference

Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1.

2 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Differentiation of 3T3-L1 fibroblasts to adipocytes induced by transfection of ras oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

The role of the transcription factor Sp1 in regulating the expression of the WAF1/CIP1 gene in U937 leukemic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Radiation-induced cell cycle arrest compromised by p21 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Human DNA-(Cytosine-5) Methyltransferase-PCNA Complex as a Target for p21 WAF1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Role of the CCAAT/Enhancer Binding Protein-α Transcription Factor in the Glucocorticoid Stimulation of p21 Gene Promoter Activity in Growth-arrested Rat Hepatoma Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Cellular ras activity is required for passage through multiple points of the G0/G1 phase in BALB/c 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

In vitro establishment is not a sufficient prerequisite for transformation by activated ras oncogenes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Activation of the p21Waf1/Cip1Promoter by theetsOncogene Family Transcription Factor E1AF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

A new technique for the assay of infectivity of human adenovirus 5 DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

p53 transactivation and protein accumulation are independently regulated by UV light in different phases of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Regulated ectopic expression of cyclin D1 induces transcriptional activation of the cdk inhibitor p21 gene without altering cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

New functional activities for the p21 family of CDK inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Sp1, but not Sp3, functions to mediate promoter activation by TGF-beta through canonical Sp1 binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Transcriptional activation of the human p21(WAF1/CIP1) gene by retinoic acid receptor. Correlation with retinoid induction of U937 cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Cooperating oncogenes converge to regulate cyclin/cdk complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Alternative forms of Max as enhancers or suppressors of Myc-ras cotransformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Progesterone regulates transcription of the p21(WAF1) cyclin- dependent kinase inhibitor gene through Sp1 and CBP/p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

U.V.C.-Induction of p53 activation and accumulation is dependent on cell cycle and pathways involving protein synthesis and phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Regulation of the Expression of Cyclin-Dependent Kinase Inhibitor p21 by E2A and Id Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Involvement of the Sp3 transcription factor in induction of p21Cip1/WAF1 in keratinocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Posttranscriptional stabilization underlies p53-independent induction of p21WAF1/CIP1/SDI1 in differentiating human leukemic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

High-Intensity Raf Signal Causes Cell Cycle Arrest Mediated by p21Cip1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Ras Activity Late in G1 Phase Required for p27kip1 Downregulation, Passage through the Restriction Point, and Entry into S Phase in Growth Factor-Stimulated NIH 3T3 Fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Raf-Induced Proliferation or Cell Cycle Arrest Is Determined by the Level of Raf Activity with Arrest Mediated by p21Cip1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

p21 is a universal inhibitor of cyclin kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Involvement of p21WAF1/Cip1, CDK4 and Rb in activin A mediated signaling leading to hepatoma cell growth inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

AP2 inhibits cancer cell growth and activates p21WAF1/CIP1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

A p53-independent Pathway for Activation of WAF1/CIP1 Expression Following Oxidative Stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

7 January 2021

Glucocorticoids Stimulate p21 Gene Expression by Targeting Multiple Transcriptional Elements within a Steroid Responsive Region of the p21 Promoter in Rat Hepatoma Cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

7 January 2021

p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

7 January 2021

Nerve Growth Factor Induces Transcription of the p21 WAF1/CIP1 and Cyclin D1 Genes in PC12 Cells by Activating the Sp1 Transcription Factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203000

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203000

1 reference

Dimensions Publication ID

2 September 2017

1026534497

0 references

1 reference