Nerve Growth Factor Induces Transcription of the p21 WAF1/CIP1 and Cyclin D1 Genes in PC12 Cells by Activating the Sp1 Transcription Factor (Q41094353)

26 September 2017

title

Nerve growth factor induces transcription of the p21 WAF1/CIP1 and cyclin D1 genes in PC12 cells by activating the Sp1 transcription factor (English)

1 reference

26 September 2017

Nerve Growth Factor Induces Transcription of the p21 WAF1/CIP1 and Cyclin D1 Genes in PC12 Cells by Activating the Sp1 Transcription Factor (English)

1 reference

10.1523/JNEUROSCI.17-16-06122.1997

Crossref

DOI

https://api.crossref.org/works/10.1523/JNEUROSCI.17-16-06122.1997

8 November 2024

author name string

G. Z. Yan

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9236224

8 November 2024

E. B. Ziff

series ordinal

2

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8 November 2024

language of work or name

English

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publication date

1 August 1997

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26 September 2017

15 August 1997

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9236224

full work available at URL

8 November 2024

https://www.jneurosci.org/content/jneuro/17/16/6122.full.pdf

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http://www.jneurosci.org/cgi/content/abstract/17/16/6122

8 November 2024

online access status

open access

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https://europepmc.org/articles/PMC6568361

8 November 2024

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https://europepmc.org/articles/PMC6568361?pdf=render

8 November 2024

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9236224

https://doi.org/10.1523/jneurosci.17-16-06122.1997

8 November 2024

online access status

open access

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9236224

https://syndication.highwire.org/content/doi/10.1523/JNEUROSCI.17-16-06122.1997

8 November 2024

1 reference

10.1523/JNEUROSCI.17-16-06122.1997

Crossref

DOI

https://api.crossref.org/works/10.1523/JNEUROSCI.17-16-06122.1997

8 November 2024

published in

Journal of Neuroscience

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15 May 2020

volume

17

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6568361&resulttype=core&format=json

15 May 2020

issue

16

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15 May 2020

page(s)

6122-6132

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Overexpression of cyclin D1 and cyclin E in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis.

15 May 2020

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Nerve growth factor regulates the expression and activity of p33cdk2 and p34cdc2 kinases in PC12 pheochromocytoma cells.

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Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

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Cell cycle-specific action of nerve growth factor in PC12 cells: differentiation without proliferation

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CDK6 (PLSTIRE) and CDK4 (PSK-J3) are a distinct subset of the cyclin-dependent kinases that associate with cyclin D1.

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Identification of cells expressing a D type G1 cyclin in matured brain: implication for its role in neuronal function

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Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

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Joining the complex: cyclin-dependent kinase inhibitory proteins and the cell cycle

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Constitutive overexpression of CDK2 inhibits neuronal differentiation of rat pheochromocytoma PC12 cells

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Cyclin D1 is a nuclear protein required for cell cycle progression in G1

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Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

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Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases

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Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair.

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Regulation of p21WAF1/CIP1 expression through mitogen-activated protein kinase signaling pathway

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Nerve growth factor-induced transformation of immature chromaffin cells in vivo into sympathetic neurons: effect of antiserum to nerve growth factor

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Sequencing of the rat light neurofilament promoter reveals differences in methylation between expressing and non-expressing cell lines, but not tissues

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Cell cycle regulation by the retinoblastoma family of growth inhibitory proteins

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Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter

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A bipotential neuroendocrine precursor whose choice of cell fate is determined by NGF and glucocorticoids.

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Immediate upstream promoter regions required for neurospecific expression of SNAP-25.

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Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivators

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The CDK inhibitor p21WAF1/Cip1 is induced through a p300-dependent mechanism during NGF-mediated neuronal differentiation of PC12 cells

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Overexpression of cyclin D1 in rat fibroblasts causes abnormalities in growth control, cell cycle progression and gene expression.

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NGF regulates the PC12 cell cycle machinery through specific inhibition of the Cdk kinases and induction of cyclin D1

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Adenovirus 5 E1A proteins disrupt the neuronal phenotype and growth factor responsiveness of PC12 cells by a conserved region 1-dependent mechanism

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Interaction of the v-Rel oncoprotein with cellular transcription factor Sp1

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Cyclins, cyclin-dependent kinases and differentiation

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Cyclin D1 is an essential mediator of apoptotic neuronal cell death.

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Functional analyses of the transcription factor Sp4 reveal properties distinct from Sp1 and Sp3

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12 December 2020

p21-containing cyclin kinases exist in both active and inactive states

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12 December 2020

Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle

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12 December 2020

The cyclin-dependent kinase inhibitor p21 (WAF1) is required for survival of differentiating neuroblastoma cells

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12 December 2020

Nerve growth factor-induced fiber outgrowth from isolated rat adrenal chromaffin cells: impairment by glucocorticoids

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12 December 2020

Transforming Growth Factor β Activates the Promoter of Cyclin-dependent Kinase Inhibitor p15 through an Sp1 Consensus Site

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Synergistic activation by the glutamine-rich domains of human transcription factor Sp1

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The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

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Involvement of the Sp3 transcription factor in induction of p21Cip1/WAF1 in keratinocyte differentiation

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c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II

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Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937.

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Nerve growth factor prevents the death and stimulates the neuronal differentiation of clonal PC12 pheochromocytoma cells in serum-free medium

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Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor

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Nerve growth factor regulates tyrosine hydroxylase gene transcription through a nucleoprotein complex that contains c-Fos

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A method for isolation of intact, translationally active ribonucleic acid.

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Cloning of an intrinsic human TFIID subunit that interacts with multiple transcriptional activators

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Expression of the positive regulator of cell cycle progression, cyclin D3, is induced during differentiation of myoblasts into quiescent myotubes.

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12 December 2020

Nerve growth factor-induced differentiation of PC12 cells: evaluation of changes in RNA and DNA metabolism

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Silencer elements modulate the expression of the gene for the neuron-glia cell adhesion molecule, Ng-CAM.

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12 December 2020

AP2 inhibits cancer cell growth and activates p21WAF1/CIP1 expression

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12 December 2020

The retinoblastoma protein as a fundamental mediator of growth and differentiation signals

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12 December 2020

GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase

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12 December 2020

Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: superactivation by Rb requires amino acids necessary for growth suppression

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12 December 2020

Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression

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12 December 2020

Amplification and expression of the human cyclin D gene in esophageal cancer

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12 December 2020

Identification and characterization of mRNAs regulated by nerve growth factor in PC12 cells

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12 December 2020

p53 plays a regulatory role in differentiation and apoptosis of central nervous system-associated cells

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12 December 2020

The retinoblastoma gene product regulates Sp1-mediated transcription

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Subcellular distribution of p21 and PCNA in normal and repair-deficient cells following DNA damage

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Analysis of cell cycle-related gene expression in postmitotic neurons: selective induction of Cyclin D1 during programmed cell death

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Reduced cyclin D1 expression in the cerebella of nutritionally deprived rats correlates with developmental delay and decreased cellular DNA synthesis

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p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage

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Nerve growth factor-treated, neurite-bearing PC12 cells continue to synthesize DNA

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Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

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The DNA sequence encompassing the transcription start site of a TATA-less promoter contains enough information to drive neuron-specific transcription

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Novel DNA binding proteins participate in the regulation of human neurofilament H gene expression

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Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

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12 December 2020

Effect of nerve growth factor on the expression of cell cycle regulatory proteins in PC12 cells: dissection of the neurotrophic response from the anti-mitogenic response

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Microtubule-associated-protein (MAP) kinase activated by nerve growth factor and epidermal growth factor in PC12 cells. Identity with the mitogen-activated MAP kinase of fibroblastic cells

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MN20, a D2 cyclin, is transiently expressed in selected neural populations during embryogenesis.

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Effect of protein synthesis inhibitors on growth factor activation of c-fos, c-myc, and actin gene transcription

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Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/CIP1, expression in the absence of p53.

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12 December 2020

Induction of p21 (WAF-1/CIP1) during differentiation

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12 December 2020

Ionic responses and growth stimulation induced by nerve growth factor and epidermal growth factor in rat pheochromocytoma (PC12) cells

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12 December 2020

Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.

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12 December 2020

Unscheduled expression of cyclins D1 and D3 in human tumour cell lines

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12 December 2020

Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain

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12 December 2020

Cyclin D1 provides a link between development and oncogenesis in the retina and breast

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A (G+C)-rich motif in the aldolase C promoter functions as a constitutive transcriptional enhancer element

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Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins

1 reference

12 December 2020

10.1523/JNEUROSCI.17-16-06122.1997

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6568361&resulttype=core&format=json

15 May 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6568361&resulttype=core&format=json

15 May 2020

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