Suppression of MicroRNA 200 Family Expression by Oncogenic KRAS Activation Promotes Cell Survival and Epithelial-Mesenchymal Transition in KRAS-Driven Cancer (Q37339461)

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scientific article published on 22 August 2016

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English	Suppression of MicroRNA 200 Family Expression by Oncogenic KRAS Activation Promotes Cell Survival and Epithelial-Mesenchymal Transition in KRAS-Driven Cancer	scientific article published on 22 August 2016

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scholarly article

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Europe PubMed Central

PMC publication ID

19 August 2017

Suppression of MicroRNA 200 Family Expression by Oncogenic KRAS Activation Promotes Cell Survival and Epithelial-Mesenchymal Transition in KRAS-Driven Cancer (English)

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Europe PubMed Central

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19 August 2017

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author name string

Xiaomin Zhong

1

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19 August 2017

Lan Zheng

2

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19 August 2017

Jianfeng Shen

3

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19 August 2017

Dongmei Zhang

4

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19 August 2017

Minmin Xiong

5

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19 August 2017

Youyou Zhang

6

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19 August 2017

Xinhong He

7

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19 August 2017

Janos L Tanyi

8

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19 August 2017

Feng Yang

9

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19 August 2017

Kathleen T Montone

10

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19 August 2017

Xiaojun Chen

11

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19 August 2017

Congjian Xu

12

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19 August 2017

Andy P Xiang

13

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19 August 2017

Qihong Huang

14

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19 August 2017

Xiaowei Xu

15

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19 August 2017

Lin Zhang

16

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19 August 2017

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publication date

22 August 2016

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19 August 2017

Molecular and Cellular Biology

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19 August 2017

36

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19 August 2017

21

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19 August 2017

2742-2754

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19 August 2017

The microRNA-200/Zeb1 axis regulates ECM-dependent β1-integrin/FAK signaling, cancer cell invasion and metastasis through CRKL

1 reference

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Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression

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Drugging the undruggable RAS: Mission possible?

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P-Akt/miR‑200 signaling regulates epithelial-mesenchymal transition, migration and invasion in circulating gastric tumor cells

1 reference

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Genome-wide identification of miR-200 targets reveals a regulatory network controlling cell invasion

1 reference

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Specificity protein 1 (Sp1) maintains basal epithelial expression of the miR-200 family: implications for epithelial-mesenchymal transition

1 reference

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The ZEB1 transcription factor acts in a negative feedback loop with miR200 downstream of Ras and Rb1 to regulate Bmi1 expression

1 reference

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Conserved miR-8/miR-200 defines a glial niche that controls neuroepithelial expansion and neuroblast transition

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Identification of an enhancer that increases miR-200b~200a~429 gene expression in breast cancer cells.

1 reference

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Tumour angiogenesis regulation by the miR-200 family

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The Pitx2:miR-200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation.

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Epigenetic modulation of the miR-200 family is associated with transition to a breast cancer stem-cell-like state

1 reference

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Activated K-Ras and INK4a/Arf deficiency promote aggressiveness of pancreatic cancer by induction of EMT consistent with cancer stem cell phenotype

1 reference

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Pten loss and RAS/MAPK activation cooperate to promote EMT and metastasis initiated from prostate cancer stem/progenitor cells

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miR-200bc/429 cluster modulates multidrug resistance of human cancer cell lines by targeting BCL2 and XIAP

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RAS oncogenes: weaving a tumorigenic web

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Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization

1 reference

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Retracted: Activated K-ras and INK4a/Arf Deficiency Cooperate During the Development of Pancreatic Cancer by Activation of Notch and NF-κB Signaling Pathways

1 reference

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miR-200c is upregulated by oxidative stress and induces endothelial cell apoptosis and senescence via ZEB1 inhibition

1 reference

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Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway

1 reference

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miR-200c regulates induction of apoptosis through CD95 by targeting FAP-1

1 reference

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ERK2 but not ERK1 induces epithelial-to-mesenchymal transformation via DEF motif-dependent signaling events

1 reference

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Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells

1 reference

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The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

1 reference

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Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression

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Ras oncogenes: split personalities

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12 December 2020

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10.1128/MCB.00079-16

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

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