The regulation of cellular iron metabolism (Q36974377)

17 August 2017

1 reference

title

The regulation of cellular iron metabolism (English)

1 reference

17 August 2017

Anita C G Chua

1

1 reference

17 August 2017

Ross M Graham

series ordinal

2

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17 August 2017

Debbie Trinder

series ordinal

3

1 reference

17 August 2017

John K Olynyk

series ordinal

4

1 reference

17 August 2017

language of work or name

1 reference

1 January 2007

1 reference

Critical Reviews in Clinical Laboratory Sciences

17 August 2017

published in

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17 August 2017

volume

44

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17 August 2017

issue

5-6

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17 August 2017

page(s)

413-459

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A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

17 August 2017

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Cloning and characterization of a mammalian proton-coupled metal-ion transporter

21 January 2018

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Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse

21 January 2018

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Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family

21 January 2018

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A novel mammalian iron-regulated protein involved in intracellular iron metabolism

21 January 2018

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Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter

21 January 2018

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A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation

21 January 2018

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LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity

21 January 2018

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Hepcidin, a urinary antimicrobial peptide synthesized in the liver

21 January 2018

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An iron-regulated ferric reductase associated with the absorption of dietary iron

21 January 2018

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Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis

21 January 2018

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Identification of an intestinal heme transporter

21 January 2018

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Disorders of iron metabolism

21 January 2018

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The roles of iron in health and disease

21 January 2018

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Oxygen free radicals and iron in relation to biology and medicine: some problems and concepts

21 January 2018

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The mechanism of initiation of lipid peroxidation. Evidence against a requirement for an iron(II)-iron(III) complex

21 January 2018

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Contributions of heme and nonheme iron to human nutrition

21 January 2018

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21 January 2018

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Intestinal absorption of hemoglobin iron-heme cleavage by mucosal heme oxygenase

21 January 2018

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Identification of a human heme exporter that is essential for erythropoiesis

21 January 2018

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Characterization and partial purification of a ferrireductase from human duodenal microvillus membranes

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408360701428257

Cybrd1 (duodenal cytochrome b) is not necessary for dietary iron absorption in mice

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408360701428257

The Steap proteins are metalloreductases

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408360701428257

Nramp2 expression is associated with pH-dependent iron uptake across the apical membrane of human intestinal Caco-2 cells

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408360701428257

Regulation of iron metabolism by hepcidin

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408360701428257

The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408360701428257

The role of endocytosis in transferrin uptake by reticulocytes and bone marrow cells

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408360701428257

Severe iron deficiency anemia in transgenic mice expressing liver hepcidin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Delayed hepcidin response explains the lag period in iron absorption following a stimulus to increase erythropoiesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Radioimmunochemical measurement of the transferrin receptor in human trophoblast and reticulocyte membranes with a specific anti-receptor antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Intracellular processing of transferrin and iron by isolated rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Non-ferritin, non-heme iron pools in rat tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

The ferritins: molecular properties, iron storage function and cellular regulation

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408360701428257

Loops and bulge/loops in iron-responsive element isoforms influence iron regulatory protein binding. Fine-tuning of mRNA regulation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Modulation of iron metabolism in monocyte cell line U937 by inflammatory cytokines: changes in transferrin uptake, iron handling and ferritin mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Mineralization in ferritin: an efficient means of iron storage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Ferroportin-mediated mobilization of ferritin iron precedes ferritin degradation by the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Effect of actinomycin D, cycloheximide, and acute blood loss on ferritin synthesis in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Formation of hydroxyl radicals in the presence of ferritin and haemosiderin. Is haemosiderin formation a biological protective mechanism?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Body iron excretion in man: a collaborative study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Physiology and molecular biology of dietary iron absorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Perspectives on nutritional iron deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Structure of human lactoferrin at 3.2-A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Structure of the human transferrin receptor-transferrin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Human transferrin: cDNA characterization and chromosomal localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

New perspectives on the structure and function of transferrins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

The plasma-to-cell cycle of transferrin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

The human transferrin receptor gene: genomic organization, and the complete primary structure of the receptor deduced from a cDNA sequence

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408360701428257

Primary structure of human transferrin receptor deduced from the mRNA sequence

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408360701428257

Genetic disorders affecting proteins of iron metabolism: clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Crystal structure of the ectodomain of human transferrin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

pH and the recycling of transferrin during receptor-mediated endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

The effect of the iron saturation of transferrin on its binding and uptake by rabbit reticulocytes

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408360701428257

Human transferrin receptor: expression of the receptor is assigned to chromosome 3

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408360701428257

The transferrin receptor: role in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Identification of an erythroid active element in the transferrin receptor gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Intravesicular pH and iron uptake by immature erythroid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Changes in the uptake of transferrin-free and transferrin-bound iron during reticulocyte maturation in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Inhibition of reticulocyte iron uptake by NH4Cl and CH3NH2

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

The iron transport protein NRAMP2 is an integral membrane glycoprotein that colocalizes with transferrin in recycling endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Association of the transferrin receptor in human placenta with HFE, the protein defective in hereditary hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

The hemochromatosis protein HFE competes with transferrin for binding to the transferrin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Transferrin receptor 2: continued expression in mouse liver in the face of iron overload and in hereditary hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Expression of transferrin receptor 2 in normal and neoplastic hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Localization of the iron-regulatory proteins hemojuvelin and transferrin receptor 2 to the basolateral membrane domain of hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Transferrin receptor 2 protein is not expressed in normal erythroid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Transferrin receptor is necessary for development of erythrocytes and the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Transferrin receptor 2-alpha supports cell growth both in iron-chelated cultured cells and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary hemochromatosis protein HFE

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Transferrin receptor 2 mediates a biphasic pattern of transferrin uptake associated with ligand delivery to multivesicular bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Co-localization of the mammalian hemochromatosis gene product (HFE) and a newly identified transferrin receptor (TfR2) in intestinal tissue and cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Effects of cell proliferation on the uptake of transferrin-bound iron by human hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Regulation of transferrin receptor 2 protein levels by transferrin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Diferric transferrin regulates transferrin receptor 2 protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Identification and characterization of a second mouse Nramp gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

The human Nramp2 gene: characterization of the gene structure, alternative splicing, promoter region and polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: implications for regulation and cellular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Iron-dependent regulation of the divalent metal ion transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Localisation of divalent metal transporter 1 (DMT1) to the microvillus membrane of rat duodenal enterocytes in iron deficiency, but to hepatocytes in iron overload

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Dynamic Traffic through the Recycling Compartment Couples the Metal Transporter Nramp2 (DMT1) with the Transferrin Receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Nramp 2 (DCT1/DMT1) expressed at the plasma membrane transports iron and other divalent cations into a calcein-accessible cytoplasmic pool

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

HFE gene knockout produces mouse model of hereditary hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Mechanism of increased iron absorption in murine model of hereditary hemochromatosis: increased duodenal expression of the iron transporter DMT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Nontransferrin-bound iron uptake by hepatocytes is increased in the Hfe knockout mouse model of hereditary hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Role of the ferroportin iron-responsive element in iron and nitric oxide dependent gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

The role of the iron responsive element in the control of ferroportin1/IREG1/MTP1 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Regulation of reticuloendothelial iron transporter MTP1 (Slc11a3) by inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

A mutation in SLC11A3 is associated with autosomal dominant hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Autosomal dominant reticuloendothelial iron overload associated with a 3-base pair deletion in the ferroportin 1 gene (SLC11A3)

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Ceruloplasmin metabolism and function

21 January 2018

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https://api.crossref.org/works/10.1080%2F10408360701428257

Familial apoceruloplasmin deficiency associated with blepharospasm and retinal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

A mutation in the ceruloplasmin gene is associated with systemic hemosiderosis in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron efflux

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Characterization, mapping, and expression of the human ceruloplasmin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Complete cDNA sequence of human preceruloplasmin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Expression of the ceruloplasmin gene in the human retina and brain: implications for a pathogenic model in aceruloplasminemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Cellular expression of ceruloplasmin in baboon and mouse lung during development and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Role of the liver in normal iron metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

The control of hepatic iron uptake: correlation with transferring synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Interferon/pegylated interferon and ribavirin in HCV-associated kidney disease with or without cryoglobulinemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Uptake and subcellular processing of 59Fe-125I-labelled transferrin by rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Inhibition of uptake of transferrin-bound iron by human hepatoma cells by nontransferrin-bound iron

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

A multicompartmental model of fluid-phase endocytosis in rabbit liver parenchymal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Non-transferrin-bound iron and hepatic dysfunction in African dietary iron overload

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Congenital Atransferrinemia A Case Report and Review of the Literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Non-transferrin-bound iron species in the serum of hypotransferrinaemic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Serum non-transferrin-bound iron in beta-thalassaemia major patients treated with desferrioxamine and L1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

The importance of non-transferrin bound iron in disorders of iron metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Efficient clearance of non-transferrin-bound iron by rat liver. Implications for hepatic iron loading in iron overload states

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Tissue distribution and clearance kinetics of non-transferrin-bound iron in the hypotransferrinemic mouse: a rodent model for hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Characterisation of citrate and iron citrate uptake by cultured rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Activation of an iron uptake mechanism from transferrin in hepatocytes by small-molecular-weight iron complexes: implications for the pathogenesis of iron-overload disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Zip14 (Slc39a14) mediates non-transferrin-bound iron uptake into cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Multidentate pyridinones inhibit the metabolism of nontransferrin‐bound iron by hepatocytes and hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

21 January 2018

Hepatic iron metabolism.

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Limited iron export by hepatocytes contributes to hepatic iron-loading in the Hfe knockout mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

The regulation of iron release from the perfused rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Regulating the fate of mRNA: the control of cellular iron metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Iron Regulates the Intracellular Degradation of Iron Regulatory Protein 2 by the Proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Iron increases expression of iron-export protein MTP1 in lung cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Regulation of ferritin synthesis and iron regulatory protein 1 by oxygen in mouse peritoneal macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Hypoxia post-translationally activates iron-regulatory protein 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Oxygen and iron regulation of iron regulatory protein 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Nitric oxide signaling to iron-regulatory protein: direct control of ferritin mRNA translation and transferrin receptor mRNA stability in transfected fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Nitric oxide and oxidative stress (H2O2) control mammalian iron metabolism by different pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Nitrogen monoxide-mediated control of ferritin synthesis: implications for macrophage iron homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Regulation of ferritin genes and protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

The IL-6- and lipopolysaccharide-induced transcription of hepcidin in HFE-, transferrin receptor 2-, and beta 2-microglobulin-deficient hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Regulation of hepcidin transcription by interleukin-1 and interleukin-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Perspectives on oxygen sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Purification and characterization of hypoxia-inducible factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Oxygen-regulated Transferrin Expression Is Mediated by Hypoxia-inducible Factor-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

HIF-1-mediated activation of transferrin receptor gene transcription by iron chelation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Role of hypoxia-inducible factor-1 in transcriptional activation of ceruloplasmin by iron deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Rapid internalization of the transferrin receptor in K562 cells is triggered by ligand binding or treatment with a phorbol ester

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

HFE, the MHC and hemochromatosis: Paradigm for an extended function for MHC class I

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Mechanisms of iron accumulation in hereditary hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Structure, function, and diversity of class I major histocompatibility complex molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Immunohistochemistry of HLA-H, the protein defective in patients with hereditary hemochromatosis, reveals unique pattern of expression in gastrointestinal tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenum

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Structure and liver cell expression pattern of the HFE gene in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Localization of iron metabolism–related mRNAs in rat liver indicate that HFE is expressed predominantly in hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Kupffer cell staining by an HFE-specific monoclonal antibody: implications for hereditary haemochromatosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

The hemochromatosis founder mutation in HLA-H disrupts beta2-microglobulin interaction and cell surface expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Hereditary hemochromatosis: Effects of C282Y and H63D mutations on association with β 2 -microglobulin, intracellular processing, and cell surface expression of the HFE protein in COS-7 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Co-trafficking of HFE, a nonclassical major histocompatibility complex class I protein, with the transferrin receptor implies a role in intracellular iron regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Defective iron homeostasis in beta 2-microglobulin knockout mice recapitulates hereditary hemochromatosis in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Binding to the transferrin receptor is required for endocytosis of HFE and regulation of iron homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

HFE and transferrin directly compete for transferrin receptor in solution and at the cell surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Crystal Structure of the Hemochromatosis Protein HFE and Characterization of Its Interaction with Transferrin Receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Evidence for the interaction of the hereditary haemochromatosis protein, HFE, with the transferrin receptor in endocytic compartments

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

The hereditary hemochromatosis protein, HFE, specifically regulates transferrin-mediated iron uptake in HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Transferrin receptor is negatively modulated by the hemochromatosis protein HFE: implications for cellular iron homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Regulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

The haemochromatosis protein HFE induces an apparent iron-deficient phenotype in H1299 cells that is not corrected by co-expression of beta 2-microglobulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

The hemochromatosis protein HFE inhibits iron export from macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Expression of the hereditary hemochromatosis protein HFE increases ferritin levels by inhibiting iron export in HT29 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

New mutations inactivating transferrin receptor 2 in hemochromatosis type 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Targeted mutagenesis of the murine transferrin receptor-2 gene produces hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

The iron-regulatory peptide hormone hepcidin: expression and cellular localization in the mammalian kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

The solution structure of human hepcidin, a peptide hormone with antimicrobial activity that is involved in iron uptake and hereditary hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

The N-terminus of hepcidin is essential for its interaction with ferroportin: structure-function study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Expression of hepcidin is down-regulated in TfR2 mutant mice manifesting a phenotype of hereditary hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Hepcidin is decreased in TFR2 hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Hepcidin in iron overload disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

A mouse model of juvenile hemochromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Effect of hepcidin on intestinal iron absorption in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Presence of the iron exporter ferroportin at the plasma membrane of macrophages is enhanced by iron loading and down-regulated by hepcidin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Increased duodenal iron uptake and transfer in a rat model of chronic hypoxia is accompanied by reduced hepcidin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

C/EBPalpha regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism. Cross-talk between C/EBP pathway and iron metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Interleukin-6 induces hepcidin expression through STAT3

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Bone morphogenetic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Bone morphogenetic proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently of Hfe, transferrin receptor 2 (Tfr2), and IL-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

RGM is a repulsive guidance molecule for retinal axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Interaction of hemojuvelin with neogenin results in iron accumulation in human embryonic kidney 293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Expression of Rgmc, the murine ortholog of hemojuvelin gene, is modulated by development and inflammation, but not by iron status or erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Mouse Neogenin, a DCC-like molecule, has four splice variants and is expressed widely in the adult mouse and during embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Iron metabolism: iron deficiency and iron overload

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Serum transferrin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

RADIOACTIVE IRON ABSORPTION BY GASTRO-INTESTINAL TRACT : INFLUENCE OF ANEMIA, ANOXIA, AND ANTECEDENT FEEDING DISTRIBUTION IN GROWING DOGS

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

The control of iron absorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Hereditary hemochromatosis--a new look at an old disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

THE ROLE OF THE INTESTINE IN IRON KINETICS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Iron influx across the brush border of rabbit duodenum: effects of anemia and iron loading

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Expression of the duodenal iron transporters divalent-metal transporter 1 and ferroportin 1 in iron deficiency and iron overload

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Regulation of iron absorption in Hfe mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Iron-responsive elements: regulatory RNA sequences that control mRNA levels and translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

A model for the structure and functions of iron-responsive elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

TfR2 localizes in lipid raft domains and is released in exosomes to activate signal transduction along the MAPK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

Overexpression of the hereditary hemochromatosis protein, HFE, in HeLa cells induces an iron-deficient phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408360701428257

10.1080/10408360701428257

21 January 2018

Identifiers

DOI

1 reference

17 August 2017

1 reference